UCSF Radiation Oncology

Had a fantastic time at #ASTRO2025 in San Francisco - grateful for the chance to reconnect with colleagues, collaborators, and friends from around the world! @astro-org.bsky.social @ucsfradonc.bsky.social @ruehlealex.bsky.social

Hui Lin's glioma LLM study "A Clinically Aligned Embedding Model for Glioma Prognostication Via Radiology-Pathology Report Matching" featured in the Cancer Breakthroughs Session today #ASTRO25 amportal.astro.org/sessions/cb-... by @aapmhq.bsky.social @toddpawlicki.bsky.social @astro-org.bsky.social

At #ASTRO25 and looking for a new landing spot in #RadOnc? Connect with us via @ucsfradonc.bsky.social or find our experts at the conference: cancer.ucsf.edu/news/2025/09...

See highlights of @ucsfradonc.bsky.social participation at the 2025 @astro-org.bsky.social conference starting tomorrow: cancer.ucsf.edu/news/2025/09... #ASTRO2025 #UCSF

Amazing team swim w/ @sjohnliu.bsky.social @neurosurgucsf.bsky.social to support glioblastoma & pediatric cancer research- $600K+ raised at SF event! Funds raised goes directly to local cancer research institutions, @ucsfhealth.bsky.social Children's, @ucsanfrancisco.bsky.social Brain Tumor Center

Congratulations to David Raleight Lab - to investigate the genomic and biochemical mechanisms underlying differences in meningioma outcomes! @ucsfcancer.bsky.social Awarded $12M Research Grant to Improve Cancer Outcomes @neurosurgucsf.bsky.social www.newswise.com/articles/ucs...

Every $1 the NIH invests, generates $2.56 in New Economic Activity

NIH-funded research tackles America’s toughest health challenges and creates jobs nationwide. Every $1 the NIH invests in research generates about $2.56 in new economic activity, from new jobs to spin-out companies. tiny.ucsf.edu/i9bINg

Plasma proteomic analysis reveals complement system changes in irradiated female BALB/c mice during mammary carcinogenesis - Mary Helen Barcellos-HOff, et al @theaacr.bsky.social @ucsfcancer.bsky.social aacrjournals.org/cancerrescom...

Docs hope UCSF-Stanford hub can set ‘example’ Donor, schools pledge $200 million effort.

For @julianhong.bsky.social the funding opens up opportunities to explore how AI can help personalize cancer treatments - improve data sharing so that patients can more easily understand health history, build out the broader cancer knowledge database... www.sfexaminer.com/news/health/...

Congratulations to @julianhong.bsky.social & team for Project IMPACT - one of the first to be awarded by the new Weill Cancer Hub West! To build artificial intelligence systems that integrate clinical and biological data for precise, personalized cancer treatments @ucsfcancer.bsky.social

Do These Two Cancer Drugs Have What It Takes to Beat Alzheimer’s? Scientists at UCSF and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer’s, potentially slowing or even reversing its sympt...

Do These Two Cancer Drugs Have What It Takes to Beat Alzheimer’s? - Marina Sirota, Yadong Huang @gladstoneinst.bsky.social publish in @cellpress.bsky.social ! www.ucsf.edu/news/2025/07... @ucsfcancer.bsky.social @ucsanfrancisco.bsky.social @ucsfhealth.bsky.social

"A transcriptomic, proteomic, and functional genetic atlas dissects neurofibromin function in the peripheral nervous system" now in @pnas.org Harish Vasudevan Lab @ucsfcancer.bsky.social @neurosurgucsf.bsky.social www.pnas.org/doi/10.1073/...

RUN TIBURON is a fundraiser for UCSFʻs Survivorship and Wellness Health services

We are taking a moment to celebrate the courage of our @ucsfhealth.bsky.social patients, doctors, nurses, researchers, caretakers, friends, and families by participating in the Courage Over Cancer 5K & 10K Run/Walk in beautiful Tiburon! September 7th: calendar.ucsf.edu/event/courag...

Multimodal AI Shows No Evidence of Bias in Prostate Cancer Study A new study published in JCO Clinical Cancer Informatics tackles a critical challenge in cancer diagnostics: ensuring that artificial intelligence (AI) performs equitably across racially diverse patie...

New study led by Mack Roach III, MD @ucsfradonc.bsky.social tackles a critical challenge in cancer diagnostics: ensuring that AI performs equitably in prognosis for #ProstateCancer across racially diverse patient populations. www.itnonline.com/article/mult...

Congratulations to @sueyom.bsky.social & Mary Helen Barcellos-Hoff for their 2025 Innovation Award - pioneering research dedicated to exploring new indications for radiation therapy @astro-org.bsky.social @ucsfcancer.bsky.social @ucsfhealth.bsky.social www.roinstitute.org/our-impact/t...

See ""Long-Term Clinical Outcomes for Adolescent and Young-Adult Uveal Melanoma Patients Treated with Dedicated Particle-Beam Radiation" - now online! Kavita Mishra, @jescholey.bsky.social et al www.mdpi.com/2072-6694/17... @ucsfcancer.bsky.social @ucsfhealth.bsky.social @ucsanfrancisco.bsky.social

Multiplexed epigenetic memory editing using CRISPRoff sensitizes glioblastoma to chemotherapy AbstractBackground. Glioblastoma (GBM) carries a poor prognosis, and new therapeutic strategies are necessary to improve outcomes for patients with this di

Read latest from @sjohnliu.bsky.social & Lab in
Neuro-Oncology! "Multiplexed epigenetic memory editing using CRISPRoff sensitizes glioblastoma to chemotherapy" academic.oup.com/neuro-oncolo... Nature Reviews: www.nature.com/articles/s41... @neuroonc.bsky.social @neurosurgucsf.bsky.social

Congratulations to Harish Vasudevan for the Dept of Defense Synergistic Idea Award "Mapping for the RNA Splicing Landscape of NF1 & Its Impact on Neurofibromin Function Across Tissues" ! @neurosurgucsf.bsky.social @ucsfcancer.bsky.social @ucsanfrancisco.bsky.social cdmrp.health.mil/nfrp/awards/...

Congrats to graduating RadOnc Residents - med & physics! "A major milestone from wearing the hat of a trainee, to holding responsibilities & privileges of caring for our patients." - Catherine Park, Chair, Drs. Ke Sheng, Barcellos-Hoff, Braunstein, Boreta, Vasudevan @ucsanfrancisco.bsky.social

Computational Cancer Community (C3) Monthly Meeting

Join the Cancer Computational Community (C3) Lightning talks on Mon., 6/9, 10am! Hear from Labs of @ShengMPLab Wan-Jin Yeo, @chriswzou @sjohnliu.bsky.social, @McManus_Lab, Wei, Olshen calendar.ucsf.edu/event/comput... @ucsfcancer.bsky.social @ucsanfrancisco.bsky.social @ucsf-bchsi.bsky.social

Read the latest perspective piece by @sueyom.bsky.social & Mary Helen Barcellos-Hoff in @natrevcancer.nature.com @ucsanfrancisco.bsky.social @ucsfhealth.bsky.social @ucsfcancer.bsky.social

Revisiting the TGFβ paradox: insights from HPV-driven cancer and the DNA damage response - Nature Reviews Cancer Transforming growth factor-β (TGFβ) has a well-established role in malignancy and its inhibition has demonstrated strong preclinical activity. However, TGFβ blockade has repeatedly failed in clinical trials. Here, Barcellos-Hoff and Yom utilize human papillomavirus (HPV)-driven cancer as a model to explain these discrepancies and emphasize the need for refined strategies and understanding of TGFβ signalling to enhance therapeutic efficacy.

🚨 PERSEPCTIVE 🚨

TGFβ has a well-established role in cancer, yet its blockade has 🔁ly failed in trials. Barcellos-Hoff & Yom use HPV-driven cancers as a model to explain these discrepancies & emphasize the need for refined strategies to enhance therapeutic efficacy.

Considerations in Translating AI to Improve Care The potential impact of artificial intelligence (AI) on personalized medicine, clinical decision support, clinical workflow optimization, and health care management has attracted the attention of pati...

Considerations in Translating AI to Improve Care - Commentary/Oncology by @julianhong.bsky.social Divneet Mandair; Marianna Elia
@ucsfcancer.bsky.social
@ucjointcph.bsky.social
jamanetwork.com/journals/jam...

She Lost Her Tongue to Cancer, but Found Her Voice Through AI | KQED Sonya Sotinsky recorded herself speaking and reading aloud to preserve a vital part of her identity — her voice. Now, with help from artificial intelligence, she can speak again.

Sonya Sotinsky recorded herself speaking and reading aloud to preserve a vital part of her identity — her voice. Now, with help from artificial intelligence, she can speak again.

“Your voice is your identity" - Dr. @sueyom.bsky.social See latest article! "Cancer Stole Her Voice. Curse Words, Children’s Books and AI Saved It" @ucsfhealth.bsky.social @ucsfcancer.bsky.social @ucsanfrancisco.bsky.social @elevenlabs-io.bsky.social

Multi-institutional atlas of brain metastases informs spatial modeling for precision imaging and personalized therapy - Nature Communications In patients with advanced cancer, the development of brain metastasis (BM) often signals a worsening prognosis with limited therapeutic options. Here, the authors assemble a large, open-source neuroim...

Exciting paper by Olivier Morin, Dante Capaldi, Evan Porter, Steve Braunstein: Multi-institutional atlas of brain metastases informs spatial modeling for precision imaging @natcomms.bsky.social www.nature.com/articles/s41... @neurosurgucsf.bsky.social @ucsfcancer.bsky.social @ucsfimaging.bsky.social

Here’s How to Prime Tumors to be Defeated by Cancer Immunotherapy Scientists discover how to rouse the immune system around "cold" tumors, making them vulnerable to cancer-killing immune therapies with checkpoint inhibitors.

"Cold" tumors? Now treatable. Researchers found a way to make immune-resistant tumors respond to immunotherapy, expanding access for more patients. tiny.ucsf.edu/SH5822

Dr. Edward Chang poses in a blazer and white button-down shirt.

👏 Congratulations to Dr. Edward Chang on his election to the National Academy of Sciences! Dr. Chang is the first neurosurgeon to achieve this prestigious distinction since Harvey Cushing's election more than 100 years ago in 1917!
More about this historic recognition ➡️ ucsfh.org/438cefp

ASTRO's first anal cancer guideline addresses 'complicated’ treatments from ‘holistic’ view The American Society for Radiation Oncology has issued its first clinical guideline on the use of radiation therapy to treat adults with anal cancer.ASTRO developed the guideline — published in ...

ASTRO's first anal cancer guideline addresses 'complicated’ treatments from ‘holistic’ view - Mary Feng MD @gohealio.bsky.social @astro-org.bsky.social @ucsanfrancisco.bsky.social www.healio.com/news/hematol...

Loved celebrating the incredible research done by our Medical Physics trainees 🤩 Already looking forward to next year’s symposium!