Adrien Peyrache

This important study provides new insights into the synchronization of ripple oscillations in the hippocampus, both within and across hemispheres. While power is correlated across hemispheres, synchrony is significantly higher within a hemisphere than across.

doi.org/10.7554/eLif...

I am recruiting graduate students for the experimental side of my lab @mcgill.ca for admission in Fall 2026!
Get in touch if you're interested in how brain circuits implement distributed computation, including dopamine-based distributed RL and probabilistic representations.

Arrived in San Diego for my first SfN, looking forward to showing you all my work with @apeyrache.bsky.social ; untangling the contribution of inhibition to the thalamic head direction attractor 💍

Come see me tonight at the TPDA poster session or on Tuesday morning with the lab!

#SfN25

Will be presenting a poster on @apeyrache.bsky.social row, Tues AM, with an update our sequential predictive learning preprint:

-CA3-like (sparse lognormal) connectivity gives a hippocampus-like (orthogonalized) map

-non-spatial representation! splitters, lap/time cells, action plan…we got it all🤑

Five-star hydrotherapy for hardware that costs more than my car.

We recycle our probes many many times, even after chronic implants, saving $$$. Happy to share the protocol.

(And yes, I don’t have a car).

Congrats Nic and the team!
But.. received 4 November 2022?? 😱

Sosa Lab - Postdoctoral Researchers We are seeking postdocs to start in 2026!

The Sosa Lab is going to #SfN25 and actively recruiting ✨postdocs✨ with systems neuroscience experience! We study both fundamental memory processes and how memory changes during pregnancy and postpartum.

If you are interested in meeting at SfN, please email me! www.sosaneurolab.com/join/postdoc...

Great study showing how histaminergic signaling shapes head-direction cell activity in the presence of objects, with important implications for how animals get oriented. A huge amount of work, really impressive.

www.researchsquare.com/article/rs-7...

7 basic science discoveries that changed the world Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government.

A chemical extracted from carrot roots helped pave the way for flat-screen TVs, and six other discoveries that unintentionally changed the world.
Perfect talking points for when you need to defend basic science, whether it’s to your grumpy uncle or your MP.

www.nature.com/articles/d41...

3 Postdoctoral Research Fellows Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr.

🚨Job alert🚨

The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour

This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"

euraxess.ec.europa.eu/jobs/383909

How much are MPs entitled to know about research grants? Not as much as they think A parliamentary committee is asking for academics’ private information on a strange anti-DEI crusade

a gross parliamentary overreach — article by @picardonhealth.bsky.social in the globe and mail; #academicsky #neuroskyence #psychscisky www.theglobeandmail.com/gift/91587b9...

New lab colormap, courtesy of the tree outside my house.

A mean-field model of neural networks with PV and SOM interneurons reveals connectivity-based mechanisms of gamma oscillations Classic theoretical models of cortical oscillations are based on the interactions between two populations of excitatory and inhibitory neurons. Nevertheless, experimental studies and network simulatio...

Various theoretical properties derived for gamma oscillations based on canonical E-SOM-PV microcircuit connectivity using mean-field modelling, which moves beyond classic Wilson-Cowan models in important ways
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo

Post-tenure:

Extending my realm one trainee at a time.

Careful, 🍍can get viral once in the wild

Dommage que mon grand-père ne soit plus là pour voir ça, j’aurais pu lui dire que je connaissais des gens dans son journal ;)

How long did you hesitate with DuzLab?

Looking forward to seeing all the great science that will come out of @adrian-du.bsky.social’s lab, aka the DuLab!!

Congrats Adrian!

The postsubiculum as a head-direction cortex The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…

Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)

🚨new paper: the head-direction circuit as a model of primary thalamocortical system. Check this out 👇

kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩

Exactly. Yet, whether through art or science, once a new form of representation emerges, it transforms how we see. Cubism, jazz, or minimalism shift our perception of the world; complex numbers or relativity reshape our intuition of it.

Totally agree with @gershbrain.bsky.social. Science will never explain art.
Yet the two share an important trait: a constant search for new representations of nature, of data, of reality, of emotions, in forms that make sense of what once seemed inscrutable.

There are models in physics where things get easier when N->inf

It depends what you mean by “understand”

For Gallistel, it’s all about information rate, not timing. Not a model per se, but an interesting idea.
The book that everyone should read:

www.amazon.ca/Memory-Compu...

The Wu Tsai Institute at Yale is hiring another faculty member in neurocomputation. Come work with us in a growing community at the interface of neuroscience and AI!

More info below 👇

Every neuroscience lecture ever, summarized in one dog video.

I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !

With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics

🚨 New paper in Nature Methods:
HippoMaps: multiscale cartography of the human hippocampus

Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)

Led by @jordandekraker.bsky.social

docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...