Roy Perlis, MD

Targeting Schizophrenia | American Journal of Psychiatry PsychiatryOnline.org is the platform for all American Psychiatric Association Publishing journals, DSM, and bestselling textbooks, as well as APA Practice Guidelines, and continuing medical education.

Happy to have the opportunity to highlight really lovely cellular modeling work by Orhan and colleagues in AJP ... endlessly boiling the genomic ocean is not sufficient to figure out brain diseases: psychiatryonline.org/doi/10.1176/...

Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants - KFF Health News Two senior scientists say National Institutes of Health officials advised them to remove references to mRNA vaccines in grant applications, and they fear the Trump administration will abandon a promis...

kffhealthnews.org/news/article...

At NIH, ‘everyone is on edge’ as they brace for deep cuts and more centralized control As the NIH braces for cuts of up to 5,000 of its 20,000 positions, “people are scrambling and freaking out,” a researcher said.

www.statnews.com/2025/03/14/n...

>I’m afraid code is getting unwieldy and bloated. How can we make it more maintainable?
You're absolutely right. The code has become unwieldy and bloated.

(Claude, that hurts my feelings a little....)

Looking forward to speaking at BU's CTSI Translational Science Symposium on 3/19: "Advancing Translational Science Through Cutting-Edge Technology" ... registration here: www.bu.edu/ctsi/events/...

Hmm. I'm not sure this chatbot is quite ready for prime time.

Working with the smaller (smol?) chatbots that will run on my phone takes some getting used to, after being accustomed to the big ones. I was just asked whether I'm feeling overwhelming today. (I am not.)

Research Domain Criteria in NIMH Grants Using Large Language Models This cohort study uses a large language model to examine changes in research funding from the National Institute of Mental Health (NIMH) for Research Domain Criteria domains and transdiagnostic invest...

Research Domain Criteria in NIMH Grants Characterized Using Large Language Models @JAMANetworkOpen
jamanetwork.com/journals/jam...

Which Digital Health Technologies Do Older Adults Use? This Medical News article is an interview with Cornelius A. James, MD, of the University of Michigan Medical School about his recent research examining the use of digital health technologies, includin...

"The use of digital health technologies has steadily increased since the COVID-19 pandemic."

Cornelius James of the University of Michigan Medical School discusses the use of digital health technologies among older US adults with JAMA+ AI Editor in Chief @royperlis.bsky.social.

#MedSky

For those curious about the impact of the 15% IDC rate, here's data on total NIH funding by institution: brimr.org/brimr-rankin... ... and here's a brief synopsis of hardest-hit: www.forbes.com/sites/michae...

YouTube video by Saturday Night Live AI Software - SNL

6 fingers are the cherry on top: youtu.be/ua4rYsMdC4U?...

The companies paying hospitals to hand over patient data to train AI A new crop of companies is lining up to buy patient data from hospitals and sell it to those wanting to train AI or do research.

www.statnews.com/2025/01/16/h...

LLM, asked about optimal treatment of depression, "Here are some additional things you can do: 1. **Get enough sleep**: Aim for 7-10 years of psychotherapy and 75-100% of CBT." Yeah, 7-10 years should just about do it.

friend is a medical illustrator

few years ago, we were wondering when AI could do her job — getting the details right is important in this use case

since then, she's been noticing more and more news articles and such using AI generated medical images

note the 3rd forearm bone

How Honeycrisp Apples Went From Marvel to Mediocre An investigation into the Honeycrisp apple and how a complex string of events led to a decline in the quality of a beloved apple variety.

Mystery solved: www.seriouseats.com/how-honeycri...

JAMA+ AI Research and Opinion Articles from JAMA Network Explore clinical applications of AI in the JAMA Network, including research and opinion about the use of deep learning and neural networks for clinical image analysis, natural language processing, EHR...

When you need a break from cute dogs and cool science facts and posts about how great it is here compared to that other place: jamanetwork.com/channels/ai

Author Robert Califf, commissioner of the US Food and Drug Administration, joins JAMA+ AI Editor in Chief Roy Perlis to discuss AI regulation.

Listen to the episode: edhub.ama-assn.org/jn-learning/...

Quantum Resistance and the Signal Protocol The Signal Protocol is a set of cryptographic specifications that provides end-to-end encryption for private communications exchanged daily by billions of people around the world. After its publicatio...

so... 'Quantum Resistance' sounds like something from a Star Wars movie, but it's actually a strategy to protect against codebreaking by quantum computers that don't actually exist yet. Who knew? signal.org/blog/pqxdh/

Guess this is home now. (Taps microphone). This thing on?

better?