Caitlin Stewart

What’s the frequency?

In this research letter, @caitlinstewart.bsky.social & team use clonal hematopoiesis as a model for simultaneous assessment of somatic mutations across multiple biosamples.

buff.ly/6fQcHgy

@jclinical-invest.bsky.social

This has been a great team effort, big thanks to everyone involved! @mskcancercenter.bsky.social

When we compared the MAFs between sample types in CH we didn't see a significant difference however comparing these in AML and MDS we did see a difference in MDS with cfDNA from plasma being much higher than buffy coat. We hypothesize this is coming from the bone marrow but did not follow this up.

We were able to detect mutations across sample types (buffy coat DNA and saliva and blood plasma cfDNA) reliably down to 0.05%-0.1% MAF while using a single sample the limit of detection was 0.3% MAF when sequenced at high depth.

Work done in Luis Diaz's lab at @mskcancercenter.bsky.social

So proud my postdoctoral work is finally out!

We designed an assay to measure cfDNA and DNA mutations in samples collected simultaneously to lower limits of detection in liquid biopsy assays, using clonal hematopoiesis as an example.

Read the article here:
www.jci.org/articles/vie...

Controversial ‘arsenic life’ paper retracted after 15 years — but authors fight back The journal Science retracts a headline-grabbing study, but the authors vigorously defend their data and say the retraction is unwarranted.

Finally! I remember reading this at the time and not believing it.

But the authors are right in saying that to "retract because of a dispute about data interpretation, you’d have to retract half the literature”.

Interested to see what happens next.

www.nature.com/articles/d41...

Starting up OnlyLabs, where people can pay to watch researchers who used to have federal funding do Hot Uncensored Cutting Edge science experiments.

Schmidt Marine At Schmidt Marine, we created the Ocean Job Board to help drive ocean conservation forward by providing access to top jobs across the community.

Black Women in Ecology, Evolution, and Marine Science is hiring an executive director:
jobs.schmidtmarine.org/companies/bw...

Fully remote, pretty good compensation and benefits.

Climate change crafting night but I’d definitely be interested in learning more about Bad art for good if I saw it advertised.

Finally deleted twitter for good. It was just garbage on my feed at this point.

Going to be on Bluesky much more now - anyone have good recommendations of who to follow?

Looking for anything: art, science, journalism, photography, writers, whatever.

I’ll be at the Festival of Genomics and Biodata in Boston next week. Send me a message if you’ll be there and want to meet up!

For my Boston people not attending FOG, I’ll be around the 23-26 of June and would love to see you outside of the conference!

#FOGBoston

Academic paper titled: “Induction of a mismatch repair deficient genotype by tailored chemical mutagenesis in experimental models of cancer”. Published in Cancer Cell.

Happy and proud to see this out!

Congratulations to lead author @benjcrousseau.bsky.social and the rest of the Diaz team! I played a small role in this, the amount of work they did to put this together was huge.

authors.elsevier.com/c/1lFj85TA51...

I have tariffed
the penguins
that are on
Heard Island

and which
you were probably
assuming
did not export goods

forgive me
they were taking advantage of us
so cunning
and so cold

Happy April Fool's! If you didn't know, there is a traditional in the astronomy community to post joke papers to the arxiv today, so here's a few highlights. Emphasis on a few (these are just a couple of my favorites), stay tuned for the @astrobites.bsky.social review post for the full collection!🔭

A simplified hybrid capture approach retains high specificity and enables PCR-free workflow Hybrid capture is a critical technology for selective enrichment of genomic regions of interest, enabling cost-effective focused sequencing in both clinical and research applications. We present a sim...

A preprint by @elembio.bsky.social on an on flowcell simplified hybrid capture approach that retains high specificity and enables PCR-free workflow www.biorxiv.org/content/10.1...

Thank you!

I’m happy to share that I’m starting a new position as Scientific Reaearch Lead at SAIL (sail.mskcc.org) at Memorial Sloan Kettering Cancer Center! Going to be exploring the world of single cell and spatial omics again. 🧪🦠🧬

Very excited for this opportunity and to be with my MSK colleagues again!

Yes very glad to see that!

Update: apparently she declined compensation!

Senior Director - Scientific Officer Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHMI) advances the discovery and sharing of scientific knowledge to benefit us all. As a biom...

HHMI Science Department is hiring! We are looking for an outstanding immunologist/ cancer biologist to join our senior leadership team. Remote work eligible, 24 weeks a year onsite, possibility of running a small lab with HHMI support

@hhmi.bsky.social

hhmi.wd1.myworkdayjobs.com/External/job...

Tweet by Grittney Tam: I’m curious why the only woman that Illumina invited was the only speaker not compensated for her talk.

Excellent observation by my friend Grittney Tam at #AGBT2025 - all the speakers who are men were compensated by Illumina for their invited talks, but not the only woman speaker?

Post a picture you took (no description) to bring some zen to the timeline.

I’ve had whooping cough despite being vaccinated (the vaccine doesn’t work in everyone and people like me rely on herd immunity), it was awful.

Antivaxxers stopped vaccinating kids in my area and I got it.

We’ll relive the devastation soon enough and hopefully come round to vaccinate again.

A comparison between low-cost library preparation kits for low coverage sequencing bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

New preprint alert!

My first paper from working with Gencove! We looked at low cost library options for low coverage sequencing.

Check it out and come ask questions at my poster on the same topic at #AGBT24 if you’re coming!

www.biorxiv.org/content/10.1...

Red metal water bottle with white fair isle reindeer pattern on it next to a plant with googly eyes.

My work water bottle (which sits on my desk year round) is finally seasonable again.

Without downloading any new pics, where are you mentally?

Where are the other women authors? I only see Ayn Rand. Ugh.

So proud of you @aliciaandrz.bsky.social for your radical honesty about your recovery and writing this piece! I hope it sparks discussion and change.