Carrie Freed, Pharm.D., BCIDP, AAHIVP

Ooo SNAP!

Interesting!

Acceptable

Have I been working with someone who says CTX this whole time? 😱

You and me both, for the exact reason 😂

Based on the pharmacokinetic studies I’ve read with oritavancin, I doubt it would have an issue staying above that MIC, one 1,200 mg dose seemingly gets to 100 mcg/mL in the serum as a peak. Those who actually use oritavancin (I haven’t) are free to correct me though! doi:10.1007/s40801-020-00188-6

Not necessarily, but compared to other isolates identified by EUCAST, 0.125 mcg/mL is a higher MIC than the majority. It would depend on the site of infection and if > 0.125 mcg/mL concentration of oritavancin can get there adequately.

There’s no direct ECOFF on EUCAST for oritavancin for E. faecium, however out of 320 observations, 41 had an MIC of 0.125 and only 8 were above that MIC. I’d say it’s on the higher end of comfort, but no great data for clinical outcomes.

*** Except when clinically indicated 😌 Kidding. I’ll check my fridge when I get home, I’m curious now.

* For legal reasons this is a joke, and antibiotics are great when used appropriately! 😝

Me, an antimicrobial steward:

Thank you 😊

Lol. You know me so well.

Ooo, will have to look

Adding mine in 😄 happy Caturday from Wheatley and Dewey!

Agree! All our med students heavily rely on Sketchy. I haven’t dug into it yet – but I will since all of them do!

For sure, she fit it in perfectly for those in-between moments. Planning to order my set soon!

Honestly, @empiricgame.bsky.social’s card set was great to learn some of the antibiotics. My ID preceptor (back when I was training) @ashpergillus.bsky.social played with me during my rotation and I learned a ton. Planning to implement it for my students 😝

Eep, a bit scary. Not for us since we use carbapenems as our B-lactams anyway, but I’ve been OK with TZP in uncomplicated urinary ESBL infections in the past.

🔥Everyone's favorite #shorterisbetter table is updated🔥
"BALANCE is now published,
so the table is now updated!
GNB bacteremia is now listed as Bacteremia(non S.aureus)
Neary 5,000 patients have now been randomized to 1 vs. 2 Constantine Units for non S. aureus bacteremia " Dr.Spellberg #idsky

#InBALANCEWeTrust

As long as it isn’t cefdinir I’m happy.

Happy 🟪 Antibiotic Awareness Week 🟪

Along with presentations, we will be raffling off microbe pins, keychains, and gift cards!

What are you doing for #USAAW24?

#IDSky #MedSky

I feel like this has to be how ibrexafungerp was named

Happy World Antimicrobial Awareness Week #WAAW! In honor of WAAW, I wanted to do a quick word unscramble of some of our common antibiotics 💊 Can you guess them?

goodness

Always love that this is a global event 🦠🌎

Interesting! We don’t report it out like that, so luckily one less thing to worry about. I’m also team CRO but only for my personal notes since it can be taken as so many other things.

Right. I was explaining this to my PGY-1 I have on with me this month and I got her excited about the brand name, too. 😝

Always! 😝