astrocyteNet

Verfahren in Verdachtsfällen wissenschaftlichen Fehlverhaltens - Wissenschaftliche Integrität Hochschulen und außerhochschulische Forschungseinrichtungen etablieren Verfahren zum Umgang mit Vorwürfen wissenschaftlichen Fehlverhaltens. Entsprechende Regelwerke erlassen sie auf Basis einer hin- ...

#WissenschaftlicheIntegrität ganz grundsätzlich: Wie müssen Forschungseinrichtungen ihr Verfahren in Verdachtsfällen wissenschaftlichen Fehlverhaltens ausgestalten? Antwort und Orientierung gibt Leitlinie 19 des Kodex zur "Guten wissenschaftlichen Praxis":
sohub.io/zilv

Call for Symposia: Göttingen Meeting 2027
Time to take the opportunity and help to shape the Scientific Program 2027 by submitting your proposal until:

17 February 2026

Further information can be found here: web.nwg-info.de/de/conferenc...

Regionally mapped astrocytic responses to cortical and white matter stroke show differential roles in astrocyte-induced vascular remodeling Stroke is a major cause of disability. Astrocytes respond to stroke in a gradated manner, but details of that response and its consequences for tissue…

When the stars of glial scar borders and stroke recovery “have a baby”, it gives this 😅 #astrocytes #stroke #cerebrovascular

Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer’s disease - Nature Neuroscience Microglia influence amyloid-β effects on astrocyte reactivity in the living brain of individuals with Alzheimer’s disease. This phenomenon further contributes to cognitive impairment via tau phosphory...

Just published in Nat. Neurosci.

Led by J.P. Ferrari-Souza, this study used imaging & fluid biomarkers to reveal that microglia modulate Aβ-related astrocyte reactivity, which in turn contributes to AD progression.

@erzimmer.bsky.social
@natureportfolio.nature.com

www.nature.com/articles/s41...

Molecular profiling of brain endothelial cell to astrocyte endfoot communication in mouse and human - Nature Communications Deciphering body-brain communication pathways is key to a deeper understanding of brain physiology and pathology. Here, the authors define the astrocyte endfoot proteome and show dynamic vascular-to-a...

#astrocytes #endothelium #cerebrovascular 😱🤩🤩

Cover of this week's Nature showing a brain rendering Cover caption from the journal: Brain development: Our ability to process information into complex emotions, behaviours and decisions relies on the rich diversity of cell types that make up the human brain. Uncovering the molecular and cellular events that take place during brain development could reveal not only the mechanisms that give rise to this diversity but also shed light on how this process might go awry in neurodevelopmental disorders such as autism and schizophrenia. In this week’s issue, the BRAIN Initiative Cell Atlas Network (BICAN) builds on its previous work creating atlases of cell types in the adult mouse, non-human primate (NHP) and human brains to present cell-type atlases of the developing human, mouse and NHP brains. Across a suite of papers, nine of which are published in Nature, the researchers uncover the complex programs through which cell types emerge during brain development in humans and animals, revealing both the shared and unique features of the human brain. The latest work, along with future research directions, is summed up in a Perspective article by Tomasz Nowakowski and colleagues

New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) 🧠🧪🔬

An amazing set of resources for all scientists working on the brain!

🧠 Immersive feature:
www.nature.com/immersive/d4...

🧠 Perspective:
www.nature.com/articles/s41...

I’m proud to have helped launch the #PITraining survey of FKNE @fkne-scholars.bsky.social

We ask PIs to share what really matters for effective research leadership. Your feedback = better support, better science.
Take part or share:
fenskavlinetwork.org/fkne-pi-surv...
Deadline: 29 Dec 2025

Astrocytes distress triggers brain pathology through induction of δ secretase in a murine model of Alzheimer’s disease - Nature Communications The role of astrocytes in Alzheimer’s disease pathology remains insufficiently characterized. Here, the authors show that aggravated astrocyte response to Aβ causes brain inflammation, and amyloid and...

Astrocytes distress triggers brain pathology through induction of δ secretase in a murine model of Alzheimer’s disease

www.nature.com/articles/s41...

UK Glia 2026 UK Glia 2026 meeting will highlight the pivotal role of glia in brain physiology, offering invaluable insights for those investigating glia function in both health and disease. Find out more about the...

📢 June 8th-9th 2026 Bristol University 📢

We have partnered with @physoc.bsky.social to organise the 2nd meeting Bristol. It is a privilege to announce Professor Baljit Khakh, FRS will join us in the UK.

Check out the exciting programme here:
www.physoc.org/events/uk-gl...

#neuroskyence #glia

Glia gang, this is for you!

In this video by our #ElectronMicroscopy team, shows a pyramidal neuron (PyC) surrounded by 8 glia brain cells – 5 microglia (MG) and 3 oligodendrocyte progenitor cells (OPC).

🧠📈 http://microns-explorer.org

We are doing it again!!!!

Save the date for the next in-person #AstrocyteCafe next June 3-5 (2026) in Pamplona (Spain)!

We can’t wait to see many of you in person again, thanks so much to the main local organizer @maitesolas.bsky.social ♥️

Senescent astrocytic deposits drive cognitive decline by disrupting tripartite synapse in the aging brain https://www.biorxiv.org/content/10.1101/2025.10.31.685958v1

The next International Astrocyte School is coming. A wonderful and insightful week about astrocytes sprinkled with Italian food and drinks ⭐️ Highly recommend! More info: ias2026.azuleon.org
#IAS2026

Towards the ethical development of functional genomics research
www.cell.com/trends/biote...

Retinal glia regulate development of the circadian photoentrainment circuit Circadian photoentrainment depends on intrinsically photosensitive retinal ganglion cells (ipRGCs), which convey environmental light information to th…

Our latest paper is out! While the circadian photoentrainment circuit has been extensively studied, the mechanisms regulating its development remain poorly understood. Here we show that retinal Müller glia play a key role in this process. Check it out! www.sciencedirect.com/science/arti...

The blood–brain barrier In animals, the central nervous system (CNS) plays a crucial role as the primary organ responsible for integrating environmental information and coord…

Excited to share our Current Biology Primer written with Dr. Audrey Chagnot in the Brain-Body Interactions special issue!

We discuss how the BBB works, what happens when it breaks down, and why this matters for brain and body health.

@ukdri.ac.uk @thebhf.bsky.social

shorturl.at/NNc57

APOE3 astrocytes can rescue lipid abnormalities and dystrophic neurites of APOE4 human neurons #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.10.24.684364v1

Primary cilia signaling in astrocytes mediates development and regional-specific functional specification - Nature Neuroscience Astrocyte diversity is greatly influenced by local environmental modulation. Wang et al. report a critical role for astrocytic primary cilia in transmitting local cues that drive the region-specific diversification of astrocytes within the developing mouse brain.

💡 Research Spotlight: Primary cilia in astrocytes are key for their development, metabolism & synaptic regulation. Defects lead to neuronal and behavioral issues in mice, offering new insights into neurodevelopment & ciliopathies.
🔗 https://www.nature.com/articles/s41593-024-01726-z

Link between Leaky Blood-Brain Barrier and Depression TU Graz and the University of Regensburg are investigating the interaction of different cell types at the border between blood vessels and the brain. A particular focus is on sex-specific differences.

Women suffer from severe depression twice as often - but why this is so is not yet known. A possible cause could lie in the blood-brain barrier - a barrier in the brain. If it becomes "leaky", diseases can occur.

www.tugraz.at/en/news/arti...

Check out our exciting project on sex differences at the BBB

#sex_differences #astrocytes #depression
Funding: @fwf-at.bsky.social
In collaboration with @dibenedetto-lab.bsky.social

The magnificent Wills memorial building @bristoluni.bsky.social will be the location for the 2nd UK Glia meeting in June 2026

Have a look at registration information and programme information here
www.physoc.org/events/uk-gl...

C. elegans astrocytes mature in two phases from lineally distinct progenitors through CEH-43/DLX-mediated convergent transcription https://www.biorxiv.org/content/10.1101/2025.10.17.682973v1

Engrams in amygdala lean on astrocytes to solidify memories Disrupting the astrocyte-neuronal dynamic in mice destabilizes their memory of fear conditioning.

Astrocytes get less attention than their neuronal neighbors, partly because they’re harder to study. But the glial cells could help explain how memories take a more stable form after recall.

By @lauren-schneider.com

#neuroskyence

www.thetransmitter.org/memory/engra...

The astrocytic ensemble acts as a multiday trace to stabilize memory - Nature Emotional experience evokes signalling in astrocytes, which form an ensemble that is reinforced by secondary astrocytic state changes resulting from repeated experience, leading to memory stabilizatio...

Landmark publication from @junnagai.bsky.social lab!

Incredible work really detailing the neural mechanisms that recruit astrocyte ensembles ! 🤩
www.nature.com/articles/s41...

Thanks that I could be part of this collaborative efforts on this important topic, Women's Brain Foundation!

www.nature.com/articles/s44...

2/2

Sex as a biological variable (SABV) is still underconsidered in in vitro studies. In our recent review, we explain why it is imperative to address SABV across in vitro, in vivo, computational, and AI models.

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Spatially patterned cytoskeletal organization shapes astrocyte branch complexity https://www.biorxiv.org/content/10.1101/2025.10.10.681734v1

Astrocyte SEMA3C reduction improves Rett Syndrome phenotypes https://www.biorxiv.org/content/10.1101/2025.10.10.681027v1

Join the Glia community on bluesky go.bsky.app/Lyzro3M

Immediate cortical glial alterations following spinal cord injury: Evidence from a novel in vitro model Spinal cord injury (SCI) triggers immediate and widespread pathophysiological changes not only at the site of impact but also beyond it, including alterations in remote cortical regions. Here, we rep....

Did you know that spinal cord injury can induce a remote effect on the cerebral cortex?

I did not. There are very few studies about that!
 
📣 Check out our brief communication on how spinal cord injury can impact the density of cortical #astrocytes 😮

physoc.onlinelibrary.wiley.com/doi/10.1113/...