SattelyLab

Thanks to Dr. Cassandra Quave for hosting me on her Foodie Pharmacology podcast!

We discussed the molecules responsible for the properties of medicinal plants - and how my lab studies the chemistry that plants use to make them. Check it out!

t.co/nEdpoyN8QD

Discovery of homoharringtonine pathway enzymes reveals a whole plant model for coordinated biosynthesis Plants have evolved to produce diverse molecules that inhibit protein translation. A lead example is homoharringtonine (HHT), both a key tool for ribosomal profiling and an FDA-approved treatment for ...

Beautiful work by Yaereen and former lab member Kevin! Learn more about the anti-cancer compound homoharringtonine and its'biosynthesis in plants here 🌿https://www.biorxiv.org/content/10.1101/2025.08.26.672243v1

Congrats Guillermo! Fantastic finish to his ChemE REU program participation

Congrats, Jack, for a successful PhD defense🎉Party, T-shirt exchange, and a self-made Piñata

Most recent group photos! So many celebrations🥳

Couldn't have said it better! Great job @taralowensohn.bsky.social, Will, and Chun! Special thanks to the Gao lab at @stanford.edu #singlecell #plantbiology

Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III - Nature An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose curren...

@cmcclune.bsky.social will be at the GRC for Single-Cell Approaches in Plant Biology! Be on the lookout for his talk on Wednesday (8/13) at 9.10 am. Talk will be about some new approaches and discoveries recently published in Nature! www.nature.com/articles/s41... #grc #singlecell #plantbiology

Watch out for @taralowensohn.bsky.social at the GRC for Single-Cell Approaches in Plant Biology. She will be giving a talk about the pooled gene perturbation and protoplast sorting technologies developed in the lab. Interested? Talk on Monday at 8.10 pm. #grc #singlecell #plants #plantbiology

The Blum lab is recruiting graduate students and postdocs! Grad students: Reach out to me if you're interested in a rotation! Postdoc candidates: recruiting2.ultipro.com/SAL1013SIBS/...

Congrats!

Pithy coverage by @plantaeofficial.bsky.social of our recent Taxol work

#chemsky #medsky

New insights in plant gene research could boost cancer drug production A novel approach to analyzing yew tree genes has revealed key enzymes used to make Taxol, a chemotherapy drug that’s long been difficult and costly to produce.

Great article in today’s Stanford Report on our recent work deciphering how yew trees produce Taxol

@sattelylab.bsky.social news.stanford.edu/stories/2025...

Thanks to @frankelab.bsky.social 🌱

Fresh off the press! Check out the newest paper from the Sattely lab and @pollyfordyce.bsky.social lab! Spearheaded by @cmcclune.bsky.social #plants #plantbiology #anticancer #drug #taxol

Biochemical breakthrough paves way to reliable supply of anticancer drug ‘Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees.

Thanks to Jakob Franke for highlighting the Taxol/FoTO1 gene discovery and the mpXsn approach spearheaded by @cmcclune.bsky.social in @nature.com! Check it out here: www.nature.com/articles/d41... #plants #anti-cancer #singlecell #plantbiology

Preprint for the exciting, upcoming Nature paper! @cmcclune.bsky.social, Jack, Chloe, and Ricardo from the Sattely lab (in collaboration with @pollyfordyce.bsky.social) discovered genes for the anti-cancer drug Taxol pathway - plus a gene boosting the production of a bottleneck intermediate!

Working in science is particularly challenging these days, but hopefully, your plants offer a daily dose of joy. #plants

Congrats @caseyvchan.bsky.social to a successful Qual exam!!!😀

The 1st Annual Bay Area Plant Hub recently concluded, and it was a resounding success! We thoroughly enjoyed connecting with everyone. Hope you had a chance to stop by @caseyvchan.bsky.social 's and @taralowensohn.bsky.social 's posters. Plus listen to an intriguing discussion with Beth and others 🌱

🌱 Elizabeth Sattely, Stanford Chemical Engineering professor, explores how plants turn CO2 & sunlight into molecules that boost resilience & human health. Her work aims to create crops resilient to climate change & disease, improving global food systems. #SustainableAgriculture 🌍🍃