King Lab at McGill University

Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut - Nature Biotechnology Profiling host RNA shed in feces reveals disease states in the gut.

Another banger from the @harriswang.bsky.social Lab this month!

“Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut” www.nature.com/articles/s41...

What an accomplishment Michele, congrats!!!!

So so grateful to all donors and to the fantastic TFRI team!

Junior Group Leader for RNA-Biology, RNA-Technology or RNA-Medicine (f/m/d) - Würzburg (Stadt), Bayern (DE) job with Helmholtz-Institut für RNA-basierte Infektionsforschung (HIRI) | 12844907 #RNAexcellence Junior Group Leader Positions (f/m/d) Job advertisement no.:   089/2025 Starting date:                  As soon as possible. The con...

🚨 A fantastic opportunity to join HIRI to start your research group on RNA Biology 👇 www.nature.com/naturecareer...

Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mi…

📚NEW #gdTcell PAPER ALERT! 'Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling' is now out in @mucosalimmunol.bsky.social! #gastrosky #GIsky #IBDsky Join us for a Bluetorial 🧵...

👇🏻👇🏻

Antigen-presenting cells as arbiters of mucosal tolerance and immunity Nature Immunology - Brown and colleagues review the heterogeneity of mucosal antigen-presenting cells that orchestrate T cell immunity to intestinal antigens.

Excited to share our review on Thetis cells and dendritic cells, and their roles in mucosal immunity and tolerance @natimmunol.nature.com rdcu.be/eLtB1

Home - Zwick Lab Our organs don’t just grow once – they grow with us. While some are more adaptable than others, many remodel throughout life to meet the body’s changing needs, from daily challenges to the extraordina...

The Zwick Lab website is live! 🔬🌀🌈
Check out our research and team at www.zwicklab.org

Group 3 innate lymphoid cell-derived CSF2 tunes homeostasis of tissue macrophages and neutrophils Mucosal surfaces are complex ecosystems that rely on continuous communication between host and the inhabiting microbiota to sustain immune balance and health. The vast complexity of microbial communit...

Group 3 innate lymphoid cell-derived CSF2 tunes homeostasis of tissue macrophages and neutrophils from @sltai.bsky.social @theonlylabever.bsky.social and colleagues: www.mucosalimmunology.org/article/S193...

Happy to share that my first first-authored paper is finally out in @mucosalimmunol.bsky.social in time for the long weekend!
This work would not have been possible without the current and past members of @theonlylabever.bsky.social
Check it out here:
www.sciencedirect.com/science/arti...

In our latest work we've explored associations between the fecal bile acid pool and helminth infection status in school aged children in Uganda. Have a read and see what we found!

Associations between helminth infection status and the composition and concentration of fecal bile acids in school-age children in Uganda - Scientific Reports Scientific Reports - Associations between helminth infection status and the composition and concentration of fecal bile acids in school-age children in Uganda

Delighted to share my latest publication as a PhD candidate in @drlarey.bsky.social’s lab at @uvicscience.bsky.social!
With our international collaborators we’re excited to share our findings on the associations between #helminths and fecal bile acids! 🪱

doi.org/10.1038/s415...

Immunotherapy researcher Miriam Merad from Icahn Mount Sinai says the reason that cancer research has slowed is because of funding issues, which is something taxpayers don’t have to accept.

“We fight for patients, we fight for science, and we have to fight for progress.”
#STATSummit

Awesome, congrats Marcel and team!!

Excited to see the PhD work led by Sarah Danchuk published today. Virulence hierarchies within the Mycobacterium tuberculosis complex. Thanks to all the authors and collaborators, and especially kudos to Sarah: www.pnas.org/doi/10.1073/...

Gut mucosal immune responses – Implications for celiac disease and food allergy The intestinal mucosa employs a diverse set of defense mechanisms—from mucosal barrier regulation to immunoregulatory pathways—to maintain homeostasis…

SMI member Valerie Abadie reviews gut mucosal immune responses and their implications for celiac disease and food allergy at Seminars in Immunology: www.sciencedirect.com/science/arti...

#SMIMemberPaper #MucosalImmunology #Immunology

Heterozygosity for Crohn’s disease risk allele of ATG16L1 promotes unique protein interactions and protects against bacterial infection ATG16L1T300A is associated with Crohn’s disease and causes immune dysfunction in mouse models, yet a plurality of humans are heterozygous carriers. Yao, Rudensky, et al. find that the ATG16L1 disease ...

Very cool paper from @cadwelllab.bsky.social showing a trade off between host defense and susceptibility to Crohn’s disease

Heterozygosity for Crohn’s disease risk allele of ATG16L1 promotes unique protein interactions and protects against bacterial infection: Immunity www.cell.com/immunity/ful...

Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis @biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...

Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.

Assistant Professor (Tenure Track), Department of Pharmacology and Therapeutics, Pluripotent Stem Cells in Regenerative Medicine (L000066) Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...

Do you have expertise in stem cell biology and interesting in pulmonary health?

Apply to our tenure-track position at McGill University in beautiful Montreal and join us!!! See below for the link:

mcgill.wd3.myworkdayjobs.com/en-US/McGill...

I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events.

Deafening Quiet from the Scientific Establishment

jeremymberg.github.io/jeremyberg.g...

1/14

A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine

Thanks Payal. I had a fantastic visit!

Beautiful talk by @ikinglab.bsky.social today @nyulangone.bsky.social talking IFNg, type 2, parasites, disease tolerance and gut:stroma axis. gorgeous microscopy and insightful new Frontiers in Hpb infections. 👏👏

Microbiome and Pain: Unraveling the Gut-Brain connection Join us for this co-hosted half-day seminar with the Alan Edwards Centre for Research on Pain. Keynote speaker: Dr David Bulmer.

The McGill Centre for Microbiome Research is hosting a mini-symposium Oct 21! Microbiome and Pain: Unraveling the Gut-Brain connection. Sign up for a great morning of student talks, networking and a keynote from Dr. David Bulmer! www.eventbrite.ca/e/microbiome...

We are looking to hire post-docs to work on T cell responses to M. tuberculosis infection using murine and NHP models. If you know T cells and wanna work on the top global infectious killer check us out. BSL3 experience not required. The NIH intramural program in Bethesda MD is an amazing place!

@governor.ny.gov @lizkrueger.bsky.social New York’s biomedical economy is at a tipping point! Investment in science pay off! For heath, for jobs, and for the economy!

New Postdoc position as part of the recently awarded MRC Core in Exposome Immunology, led by Jo Konkel here @lydiabeckeriii.bsky.social. Job ad and more info below:
www.jobs.manchester.ac.uk/Job/JobDetai...

www.bmh.manchester.ac.uk/research/ins...

Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be."

Screenshot of graphic showing that the HPV vaccine has reduced cervical cancer incidence by 90%.

RFK Jr. went on Fox News today to claim that HHS has had “no successes” in the past 40 years.

I beg to differ.

Figure from Lei et al., NEJM 2020. Link below.