@ajaichari.bsky.social @drkomanduri.bsky.social
18.10.2025 02:34 β π 0 π 0 π¬ 0 π 0
Our strategy to address relapse after BCMA CAR T-cell therapy depends on whether a patient has rapid aggressive relapse (i.e., extramedullary disease, plasma cell leukemia, or rapidly rising myeloma markers or disease burden) or biochemical/clinical relapse without aggressive features. For all patients, talquetamab or another GPRC5D bispecific is a preferred approach. For rapid aggressive relapse, high dose cytotoxic chemotherapy or salvage autologous stem cell transplant may also be considered. For other relapses, a retrial of BCMA targeted therapy or various proteasome inhibitor and immunomodulatory drug combinations can be considered. The rapidly changing landscape of available drugs means that several novel approaches or clinical trials may also be available for patients.
How should we choose optimal salvage treatments following BCMA-directed CAR-T therapy in multiple myeloma?
Check out our review article out today summarizing recent studies and our approach to therapy sequencing from our team at @ucsfcancer.bsky.social #MMsm #myeloma
dx.doi.org/10.1080/1750...
18.10.2025 02:29 β π 1 π 1 π¬ 1 π 0
I enjoyed working with colleagues and mentors at Dartmouth to create and lead these workshops for medical students and faculty to develop skills in addressing microaggressions and bias in their roles as health care professionals, educators, and leaders. Learn more belowπ @aamctoday.bsky.social
28.04.2025 04:06 β π 1 π 2 π¬ 0 π 0
At #Tandem25: @drkomanduri.bsky.social
accepts the ASTCT advocacy award. Congratulations Dr. Komanduri, we commend you for your dedication to advancing our field!
15.02.2025 00:31 β π 13 π 4 π¬ 1 π 0
Grateful to Clinical Lymphoma, Myeloma & Leukemia, co-authors, and @ash-hematology.bsky.social for the opportunity to share this research on targeted neurocognitive testing after anti-CD19 and anti-BCMA #CART cell therapy. #lymsm #mmsm
clinical-lymphoma-myeloma-leukemia.com/article/S215...
26.12.2024 20:03 β π 0 π 0 π¬ 1 π 0
DoC-IT aims to conduct innovative clinical informatics research, train the next generation of experts in the field, and guide health system implementation to improve care for all.
docit.ucsf.edu
Geriatric Hematologist l Myeloid Cancer | @WilmotCancer #geriheme #digitalhealth Research Program l SIOG Board & National Rep Committee Chair l ASH Education Affairs Committee | @AmerGeriatrics Research Committee | @JGeriOnc Associate Editor
The UCSF Action Research Center for Health leads research to transform systems & create conditions so everyone can live good & healthy lives.
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π LinkedIn: bit.ly/ARCforHealthLinkedIn
π₯οΈ ARCforHealth.ucsf.edu
Account of the American Society of Clinical Oncology & its affiliate the Association for Clinical Oncology.
The worldβs leading professional organization representing more than 50,000 oncology professionals caring for people with cancer.
Professor, UCSF hematology/BMT. Translational researcher interested in leukemia, MDS, HLH, MRD, post-HCT relapse, GVHD, & immune recon. Photos (Instagram): pyknosis
Editor in Chief, JAMA & JAMA Network @jama.com jama.com
Professor, Epidemiology & Biostatistics and Medicine, UCSF https://profiles.ucsf.edu/kirsten.bibbins-domingo
scientist-physician-teacher
views are my own
Probably off thinking about scientific data or college sports.
ML for healthcare and health equity. Assistant Professor at UC Berkeley and UCSF.
https://irenechen.net/
Geneticist whose lab does experimental evolution, using yeast as a model. Because being a footballer was never going to work out, due to lack of talent.
PI of SGD and CGD
ORCID: 0000-0002-1692-4983
JAMA is an international peer-reviewed general medical journal and a member of the JAMA Network family of journals.
π JAMA.com
Chair of the Department of Biomedical Informatics at the University of Colorado School of Medicine. Research: transcriptomics, machine learning, public data - pick two of three. He/him. Views mine, not employer's.
Chair, Department of Computational Biomedicine at Cedars-Sinai Medical Center in Los Angeles. Director, Center for Artificial Intelligence Research & Education. Atari enthusiast. Retrocomputing. Maker.
Faculty at UC San Diego. Chief Health AI Officer at UC San Diego Health. #rstats. Creator of Tidier.jl #julialang. #GoBlue. Views own.
Director, Center for Healthcare Innovation and Delivery Science, NYU Langone Health; #NIHRECOVER adult PI; general internist; quality/safety/healthcare delivery; mom of 3 boys. Posts are my own. #MedSky
I write about medicine at STAT. This is biology's century. Every data point has a face.
R, data, π, πΈ, π. He/him.
Believe in yourself! Work hard, never give up & anything's possible! OR: Kick back, relax & aim low: You'll never be disappointed...π I IGNORE ALL DMs!
Entrepreneur
Costplusdrugs.com
Physician/scientist, partner at Khosla Ventures, investing in the future. 25 years of experience in the intersection of AI/ML, biotech and healthcare.
Personal interests in art (painting, drawing, photography), sci-fi/fantasy, anthropology, and history.