Enya Daynes

Determining the minimum important differences for field walking tests in adults with long–term conditions: a systematic review and meta-analysis ImportanceThe minimum important difference (MID) for field walking tests aims to improve interpretation of outcomes, but the volume and heterogeneity of MIDs for these tests is challenging. We aimed to determine the MID for the 6-min walk distance (6MWD), incremental shuttle walk test (ISWT) and endurance shuttle walk test (ESWT) in adults with long-term conditions.MethodsThis systematic review included studies that generated a MID using an anchor-based approach in patients with long-term conditions for the 6MWD, ISWT or ESWT field walking tests. Studies were screened and data extracted by independent reviewers. Meta-analyses were performed using RevMan.Results42 studies were included in the analyses, involving n=13 949 participants. Of these, 12 studies involving exercise as an intervention were included in the meta-analyses to produce MIDs, presented as mean (95% confidence interval). The MID for the 6MWD was 25 m (24–26 m) for respiratory conditions, 23 m (8–37 m) for cardiac conditions and 37 m (26–49 m) for neurological/musculoskeletal conditions. The MID for the ISWT was 48 m (39–57 m) for respiratory conditions and 70 m (55–85 m) for cardiac conditions. The MID for ESWT in COPD was 159 s (94–224 s). The pooled MID across conditions within exercise interventions was 26 m (22–40 m) for the 6MWD and 53 m (44–62 m) for the ISWT, with reasonable heterogeneity (I2=48% and I2=47%, respectively).ConclusionWe propose new MIDs for exercise interventions using anchor-based methodology in long‑term conditions for the 6MWD, ISWT and ESWT. These can be used internationally for meta‑analyses where studies have used different field walking tests, to optimise trial sample size calculations, and for clinical service benchmarking.

New publication🎉🎉

Determining the minimum important differences for field walking tests in long–term conditions: systematic review & meta-analysis publications.ersnet.org/content/erre...

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🌟 Chris Brightling's granddaughter Wren has #leukaemia & is undergoing gruelling treatment heroically 👇
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Our first student presentation was third year PhD fellow Holly Drover. Holly's respiratory-themed project focuses on pulmonary rehabilitation in the UK
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Leicester locals join us 29/06 for the last 3 miles completed together.

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BBC East Midlands Today are marking 5yrs since lockdown with Sharon's story on #longCOVID and her recovery here:

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& here:
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& PHOSP rehab results here:
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Clinical characteristics and prognosis prediction in patients with #AECOPD and type 2 diabetes mellitus #T2DM: A multicenter observational study journals.sagepub.com/doi/10.1177/...

Response

Response to #PostexertionalMalaise and #Rehabilitation in #LongCOVID

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Thank you Tania!

Rehabilitation improves short-term exercise capacity and immune biomarkers in those with #postCOVIDsyndrome following hospitalisation

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ICS respiratory review - pulmonary rehab (PR) Pulmonary rehabilitation is cost-effective to the NHS as for example it reduces the number of moderate and severe exacerbations, leading to fewer hospitalisations

ICS respiratory review - #pulmonaryrehab

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ALUK recommend that ICSs introduce a single accountable rehabilitation lead & to increase uptake through an opt-out system of referral

Use of implementation science to qualitatively identify implementation determinants of COPD practice guidelines in primary care journals.sagepub.com/doi/10.1177/...

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Remote assessment of exercise capacity in adults with chronic respiratory disease: Safety, reliability and acceptability

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