Igor Randulfe

01/08/2025 e o estado de Israel está a cometer un xenocidio masivo en Gaza.
A estas alturas xa deberiamos ter establecido un bloqueo económico a Israel e deberiamos estar a articular unha alianza militar para a liberación dos palestinos e para depor ao goberno xenocida de Netanyahu.

Israel tiene armas de destrucción masiva y está asesinando a decenas de miles de personas pero, por lo que sea, no se ha formado esta vez una fuerza internacional de intervención para parar a este monstruo sediento de sangre, territorios y cadáveres.

🫁 Why do some treatments fail to produce a response in patients, while others cause severe toxicity?

Join the EORTC LCG webinar to explore how pharmacological interactions shape outcomes in thoracic oncology

🎙️ Keynote speaker: Dr Veerman
🔗 Register: eortc.wufoo.com/forms/z1ov02...
#EORTCLungCancer

🧠 Why do some patients not respond to treatment, while others face severe toxicity?

Join the EORTC Lung Cancer Group webinar to explore how pharmacological interactions shape outcomes in thoracic oncology.

🎙️ Keynote speaker: Dr Veerman
🔗 Register: eortc.wufoo.com/forms/z1ov02...

#EORTCLungCancer

En su carrera mesiánica X arrastrar a OP a una guerra regional (y mantenerse así en el poder), Netanyahu ordena el ataque de Irán. Teherán tiene ahora todo el derecho a responder con una salva de misiles contra Israel y su principal valedor, EEUU. Horas muy negras para la región.

In September, 2024, physicians working with AI did better at the Healthbench doctor benchmark than either AI or physicians alone.

With the release of o3 and GPT-4.1, AI answers are no longer improved on by physicians

Error rates appear to be dropping for newer AI models. openai.com/index/health...

Happy to share our latest work, led by Dr Monaca. In a time-dependent analysis, we show that irAEs are associated with improved outcomes in ES-SCLC. Interestingly, neither high-grade irAEs nor the use of steroids appeared to negatively impact survival. www.sciencedirect.com/science/arti...

They only tested “old,” non-reasoning models. It may still be true, but it highlights the inadequacy of traditional scientific publishing from my pov.

Video of the international student at Tufts being arrested by "federal authorities" in Massachusetts has been released and it's terrifying.

They're not even uniformed officers. Just secret police thugs in hoodies and masks.

From WCVB: youtu.be/PuFIs7OkzYY

⚡ Dr Jonathan Lim joins as Co-Guest Editor for TAM’s Special Collection on T-cell engager toxicity in solid tumours. His focus on advanced immunotherapy and first-in-human trials brings exciting translational insight.

👏 Honoured to have Professor Fiona Blackhall as Co-Guest Editor on our TAM Special Collection exploring T-cell engager toxicities in solid tumours. Her leadership in lung cancer research and innovation adds real depth to this initiative.

🔬 We're thrilled to welcome Dr. Igor Randulfe as Lead Guest Editor for our Toxicity of T-Cell Engagers in Solid Tumours Special Collection in TAM. His expertise in thoracic oncology and immunotherapy is shaping this critical series.

💥 Now open for submissions: Our new Special Collection in TAM explores the mechanisms, management, and future directions of T-cell engager toxicities in solid tumours.

Submit your research: journals.sagepub.com/topic/collec...

🗓️ Deadline: 7 Sept 2025

Not sure about the Great Wall, but today’s passport control queue at Manchester Airport might just be visible from space.

Delighted to launch our new brand collateral to the wider trust today!

#cancereducation #cancercare #bettercarebettercareers

The maneuvering you are seeing now, both in Paris & among big AI players, is a sign that insiders increasingly believe the growth of AI capabilities will continue in the future towards AGI-ish systems without hitting a wall. Many other normal considerations are taking a back seat to this belief.

Considering that, if it goes well, it will unleash a superior intelligence capable of advancing humanity to the next stage of civilization, I believe the sacrifice is worth it. In any case, the race is now unstoppable, so we'll see.

It’s official! Dr Jamie Weaver & I will now be co-leading #TheChristie International Fellowship Programme for Medical Oncology, supported by Jenny Espin.

We are happy to have 40+ clinical fellows across various tumour groups, contributing to cancer care & research.

Watch the space…more to come!

People who dismiss AI as a bubble or fad fail to grasp the meaning of exponential curves and emergent properties. It reminds me of the early days of the pandemic. Of course, there may be a wall ahead, but I would be surprised if that were the case.

Pleased to share our work comparing osimertinib vs. other EGFR TKIs for EGFR+ NSCLC. In an escalation era, earlier-gen TKIs remain viable in resource-limited settings. Notably, uncommon EGFR mutations yield worse survival. authors.elsevier.com/c/1kRzycYZOi... @fabiogomes-go.bsky.social

Just used ChatGPT Vision to decipher my own handwriting (I couldn’t figure out which medication I had written down). It worked. Feeling dumber than yesterday but smarter than tomorrow, I guess.

👨‍⚕️🏥👩‍⚕️ Are you a #YoungOncologist? Interested in a 6-8 week sabbatical?

Consider applying for #ESMO Clinical Unit Visit Fellowship to join us in Manchester at our Experimental Cancer Medicines + Advanced Immunotx & Cell Tx teams. @mcrcnews.bsky.social

🗓️ Due 24 Jan 2025

🔗 www.esmo.org/career-devel...

Limited diffusion of scientific knowledge forecasts collapse - Nature Human Behaviour Kang et al. examine how patterns of knowledge diffusion can forecast the collapse of scientific ‘bubbles’, highlighting that sustained scientific advancement requires diverse audiences.

An interesting investigation into how research bubbles occur:

Limited diffusion of scientific knowledge forecasts collapse

#metascience #cogsci

www.nature.com/articles/s41...

The danger theory of immunity revisited - Nature Reviews Immunology Thirty years ago, Polly Matzinger introduced the ‘danger theory of immunity’, which proposed that danger and damage have a decisive role in immune responses. In this Perspective, Kroemer et al. reflec...

#reviewoftheweek An interesting revisit of Polly Matzinger’s danger theory of immunity, by Guido Kroemer & Co 🦠

www.nature.com/articles/s41....

Hello to the #CancerResearch community joining @bsky.app!👋

We’ve created a ‘Manchester cancer research’ starter pack so you can find scientists, clinicians and partners working in cancer research in Manchester. 🐝 👩‍🔬

We're looking forward to making new connections and sharing our research with you.

It was a pleasure to join Jelena Spasic and colleagues at the Lung Cancer Masterclass during the Serbian Medical Society's 61st Oncology Congress, which was brilliantly organized by Nada Santrac. It was also a wonderful opportunity to fully experience Belgrade!

Amazing work to help with the great migration haha. Thanks!

Starting a list of oncology related peopl. Please tell me more to add. Or any similar listd go.bsky.app/GKXp9Fy @n8pennell.bsky.social