"Datopotamab deruxtecan induces hallmarks of immunogenic cell death" by Forveille et al. reveals that the TROP2-targeted ADC not only kills cancer cells, but also triggers ICD indicators and even acts on neighboring non-TROP2 cells. A promising angle for immunotherapy!
doi: 10.15698/cst2025.08.311
14.08.2025 19:03 — 👍 0 🔁 0 💬 0 📌 0
Jalmukhambetova et al. uncover how ROS promotes localized F-actin polymerization in the apical cortex-boosting stiffness and impairing migration, independent of total F-actin levels.
DOI: 10.15698/cst2025.08.310
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14.08.2025 19:00 — 👍 0 🔁 0 💬 0 📌 0
New in @cellstress.bsky.social: "Oxidative stress induces cortical stiffening and cytoskeletal remodelling in pre-apoptotic cancer cells"
Read it for free! 👇
(1/2)
14.08.2025 19:00 — 👍 0 🔁 0 💬 1 📌 0
Senior Scientist, Department of Biology, Emory University, Atlanta, GA.
Molecular Biologist. RNA Scientist. Yeast Geneticist 🧬. British🇬🇧. Runner 🏃🏻…. Opinions are my own.
Interests: RNA Decay, RNA Processing, RNA & Disease.
Parent. Interdisciplinary biomedical researcher. Hardline scientist. PhD (Medical Biophysics, Cellular & Molecular Biology). Faculty. New platforms and real-world impact, emphasis on scientific rigour, reproducibility and efficiency. Diverse interests.
Evolutionary biologist; Asst Prof @ UC Berkeley IntBio, MVZ Herp Curator; chem ecology, molecular/tropical biology, art, politics, frogs. Posts mine.
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#RNA biology | #single-molecule #biophysics | #structural biology | #biochemistry | #quantitative biology | #chemical biology | #synthetic biology - https://www.embl.org/groups/duss/
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