Microsoft Research

In “Ideas,” collaborators Eric Horvitz, Bruce Wittmann, Tessa Alexanian, & James Diggans discuss a red-teaming effort that exposed & secured a biosecurity vulnerability in AI-driven protein design—& what the work shows about managing AI’s dual-use risks. msft.it/6010sLYsr

Microsoft researchers reveal a confidential research effort that explored how open-source AI tools could be used to bypass biosecurity checks—and helped create fixes now influencing global standards. msft.it/6015sxXo7

Headshot of Lidong Zhou above text that reads, “Lidong Zhou received honorary fellowship from HKUST.”Behind the headshot and text is a blue to purple to pink gradient.

Lidong Zhou, Managing Director of Microsoft Research Asia, has been recognized and conferred an Honorary Fellowship by the Hong Kong University of Science and Technology for his work in advancing AI research and talent development. msft.it/6016sqSdA

Yesterday’s Microsoft Research Forum is now available on-demand! Explore
how research is driving real-world impact from fundamental exploration to advancing AI responsibly, scaling innovation through products and open
source, and driving positive change for society. www.microsoft.com/en-us/resear...

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New research from Microsoft, Drexel, and the Broad explores how generative AI could support genetic professionals in rare disease diagnosis. msft.it/6019sS3P5

Microsoft Research Forum livestream kicks off soon. Register and tune in here: www.microsoft.com/en-us/resear...

His work has not only deepened our understanding of molecular systems but also opened new directions for the future of theoretical chemistry. Congratulations again!

From Boltzmann Generators to BioEmu, his innovations in molecular sampling and protein dynamics have addressed some of the most difficult problems in statistical mechanics.

Congratulations to Frank Noé, Partner Research Manager at Microsoft Research AI for Science, who received the 2025–2026 Joseph O. Hirschfelder Prize in Theoretical Chemistry for pioneering contributions at the interface of AI and chemistry. msft.it/6015sqq4R

AI is impacting healthcare—from medical training to drug discovery. Learn how things are changing from those using, studying, and developing healthcare AI in “The AI Revolution in Medicine, Revisited” with host @peteratmsr.bsky.social. All episodes available now: www.microsoft.com/en-us/resear...

The Microsoft Research Undergraduate Internship Program offers 12-week internships in our Redmond, NYC, or New England labs for rising juniors and seniors who are passionate about technology. Apply by October 6: msft.it/6015scgSJ

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As agentic AI ushers in a new era marked by tool expansion, systems are converging, and complexity is rising. Microsoft Research explores the Model Context Protocol (MCP) as a new standard for agent collaboration across fragmented tool ecosystems. msft.it/6014scgGq

Join us on September 24 at 8 AM PT for season 2 of the Microsoft Research Forum, where we’ll explore how purposeful research is driving advancements across biology, hardware and AI. Explore the agenda and register: www.microsoft.com/en-us/resear...

RenderFormer, from Microsoft Research, is the first model to show that a neural network can learn a complete graphics rendering pipeline. It’s designed to support full-featured 3D rendering using only machine learning—no traditional graphics computation required. Learn more: msft.it/6012s9mu8

The work received the Best Paper award at ACM SIGCOMM: www.microsoft.com/en-us/resear...

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Datacenter memory and network limits are restraining AI system performance. MOSAIC uses microLEDs and a wide-and-slow optical architecture to deliver faster, longer, more reliable, and energy efficient connections that could transform AI cluster designs: msft.it/6017siEVN

Microsoft brings new network innovation to #SIGCOMM2025 in areas like optical interconnects and cellular infrastructure. Discover accepted papers, view open roles, and connect with us in Coimbra: msft.it/6011s9sd5

Headshot of Tian Xie above text that reads “Tian Xie named one of MIT Technology Review’s 2025 Innovators Under 35”.

We’re thrilled to share that Tian Xie, Principal Research Manager at Microsoft Research AI for Science, has been named to MIT Technology Review’s 2025 Innovators Under 35! Tian recently led the development of MatterGen, our generative AI model for materials discovery. msft.it/6010s9dse

Newly published in PNAS, Microsoft Research introduces the Sui Generis score, a method to measure narrative diversity in LLM outputs. The study reveals how AI storytelling often echoes plot elements creating repetitive, less unique, narratives. msft.it/6015s5Kdl

Illustrated headshots of Peter Lee, Carey Goldberg, and Dr. Zak Kohane. The AI Revolution in Medicine, Revisited runs along the bottom of the graphic.

What has AI’s impact been out in the healthcare wild? In “The AI Revolution in Medicine, Revisited” finale, Peter Lee, Carey Goldberg, and Dr. Zak Kohane explore guests’ experiences with the tech in med school, drug discovery, and beyond and look ahead. msft.it/6014snCS6

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Crescent helps make digital IDs private by preventing tracking across uses while letting users only disclose what’s necessary from their credentials: msft.it/6011snCgJ

Each Microsoft Academic Research Exchange session highlights real-world research applications, interdisciplinary collaboration, and emerging methodologies. Register here for the upcoming webinar: msft.it/6019sn7oP

For the finale of “The AI Revolution in Medicine, Revisited,” Peter Lee, Carey Goldberg, and Dr. Zak Kohane compare their predictions to insights from the series’ most recent guests, including leaders in AI-driven medicine and doctors in training. msft.it/6018snnki

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MindJourney can enable AI to navigate and interpret 3D environments from limited visual input, potentially improving performance in navigation, planning, and safety-critical tasks: msft.it/6019spq8P

In Ep. 10 of “The AI Revolution in Medicine, Revisited,” former Washington State Secretary of Health Dr. Umair Shah & Mayo Clinic CEO Dr. Gianrico Farrugia share their optimism for how AI can improve public health, healthcare delivery, & medical research. msft.it/6018sRd0p

What can domains like cybersecurity and pharma teach us about governing AI and the role of evaluation and testing? Find out in the “AI Testing and Evaluation” podcast and in a new white paper distilling insights from eight expert case studies. msft.it/6013suIdN

RetroChimera, now available on Azure AI Foundry, marks a new milestone for predicting synthesis routes to drug-like molecules, opening new possibilities for AI in drug discovery. Learn more: msft.it/6011sutzJ

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Dion is a new AI model optimization method that boosts scalability and performance over existing leading methods by orthonormalizing only a top rank subset of singular vectors, enabling more efficient training of large models such as LLaMA-3 with reduced overhead: msft.it/6018suLDa

At Microsoft Research, best-in-class resources are paired with autonomy in order to drive bold ideas into solutions used globally. It’s a workplace where collaboration, curiosity, and innovation drive every breakthrough. Explore a career at MSR: msft.it/6014sOOR6

Former Washington State Secretary of Health Dr. Umair Shah & Mayo Clinic CEO Dr. Gianrico Farrugia talk AI’s impact on public health & healthcare delivery—from emergency response to patient outcomes—in Ep. 10 of “The AI Revolution in Medicine, Revisited.” msft.it/6016s3tgG