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@genikhovich.bsky.social

Evolution of developmental mechanisms, especially axial patterning. Experimental embryology. ๐Ÿชธ๐Ÿชผ

274 Followers  |  176 Following  |  75 Posts  |  Joined: 16.11.2024  |  1.7855

Latest posts by genikhovich.bsky.social on Bluesky

Congratulations, Ocรฉane!

09.10.2025 16:07 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Cool-cool-cool

06.10.2025 19:01 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Hi, can someone point me to good commercial polyclonal anti-FMRF amide antibody, which is not from rabbit? Ideally, tested on cnidarians. Thanks in advance!

02.10.2025 18:08 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Dual Bmp-negative feedback loops modulate function of both AER and ZPA to buffer and constrain postaxial digit number | PNAS Several lines of evidence indicate that posterior (postaxial) digit number in tetrapod vertebrates is constrained to the pentadactyl state by inter...

www.pnas.org/doi/10.1073/...

27.09.2025 06:57 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Notch coordinates self-organization of germ layers and axial polarity in cnidarian gastruloids Dissociation and reaggregation experiments in several animal systems have revealed the stunning capacity of self-organization. Reaggregated early gastrula cells (here called gastruloids) of the sea an...

Sanjay's amazing story is available on www.biorxiv.org/content/10.1... Congratulations to @sanjay-n.bsky.social, @ulrichtechnau.bsky.social and everyone else ๐ŸŽ‰

18.09.2025 08:12 โ€” ๐Ÿ‘ 10    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Congratulations Venky!

16.09.2025 04:32 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Congratulations to Dr. Paul Knabl @paulknabl.bsky.social Fantastic work and excellent defense!

11.09.2025 18:02 โ€” ๐Ÿ‘ 21    ๐Ÿ” 0    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 0

Congratulations! ๐ŸŽ‰

28.08.2025 04:56 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

I don't know about "twice". My memory is crappier...

28.08.2025 04:49 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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ฮฒ-catenin-driven endomesoderm specification is a Bilateria-specific novelty - Nature Communications Lebedeva et al. show that unlike Bilateria, the embryo of the cnidarian Nematostella specifies its endomesoderm in the ฮฒ-catenin-negative domain. In contrast, subsequent ฮฒ-catenin-dependent axial patt...

Thanks Max (although it's primarily @emmanuelhaillot.bsky.social who deserves the congratulations here). May I suggest that you also look at this paper www.nature.com/articles/s41... - the fit together really well.

27.08.2025 12:42 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Segregation of endoderm and mesoderm germ layer identities in the diploblast Nematostella vectensis - Nature Communications Recent work suggested that diploblast embryos (Cnidaria) may have germ layers that are similar to those seen in bilaterians, but how these are specified remained unclear. Here, they use scRNA-seq and ...

www.nature.com/articles/s41... Cool paper by @emmanuelhaillot.bsky.social et al. from Uli Technau's group. @tclebedeva.bsky.social and I were also involved ๐Ÿ™ƒ

27.08.2025 09:27 โ€” ๐Ÿ‘ 18    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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The genomic origin of the unique chaetognath body plan - Nature Genomic, single-cell transcriptomic and epigenetic analyses show that chaetognaths, following extensive gene loss in the gnathiferan lineage, relied on newly evolved genes and lineage-specific tandem duplications, not caused by a whole-genome duplication event, to shape their distinctive body plan.

Nature research paper: The genomic origin of the unique chaetognath body plan

go.nature.com/3HAsyyV

15.08.2025 09:54 โ€” ๐Ÿ‘ 12    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Loss of Twist impairs tentacle development and induces epithelial neoplasia in the sea anemone Nematostella vectensis The basic helix-loop helix transcription factor Twist plays diverse roles in mesodermal development across bilaterians, but its function in cnidarians remains unclear. Here, we investigate the role of...

www.biorxiv.org/content/10.1...

13.08.2025 06:47 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Depletion of a neural cell adhesion molecule disrupts both epithelial and germ layer identity in sea anemone embryos Assembly of cells into epithelial layers marks the early steps of tissue organization and embryonic development in most animals. Although several conserved proteins are known to be essential for epith...

www.biorxiv.org/content/10.1...

10.08.2025 09:08 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Ctenophores possess a unique aboral organ that acts as a multisensory center, controlling complex behaviors. Weโ€™ve now created a ctenophore model integrated with our 3D volume EM data. Puts it into perspective.

Check out our recent work here: www.biorxiv.org/content/10.1...

#ctenophores #volumeEM

07.08.2025 08:18 โ€” ๐Ÿ‘ 70    ๐Ÿ” 23    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2
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Gastruloids employ an alternative morphogenetic route to generate a posterior body axis on adherent substrates Morphogenesis emerges from the integration of genetic programs with environmental signals, yet studying this interplay in embryos remains challenging due to the inherent complexity of embryonic system...

www.biorxiv.org/content/10.1...

05.08.2025 21:24 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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From genes to patterns: five key dynamical systems concepts to decode developmental regulatory mechanisms Summary: Dynamical systems theory provides a powerful quantitative and intuitive framework to understand developmental processes. This Primer brings key concepts of this framework to the ever-growing ...

A Summer reading recommendation: new primer in @dev-journal.bsky.social explains how dynamical systems theory unlocks the logic of developmental patterning

Everything from bistable switches & oscillators to phase portraits & more with Python code to explore

journals.biologists.com/dev/article/...

04.08.2025 08:44 โ€” ๐Ÿ‘ 95    ๐Ÿ” 37    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Assistant Curator of Invertebrate Zoology, Careers At Field Museum Position Assistant Curator of Invertebrate Zoology FLSA Status Exempt Department Negaunee Integrative Research Center Our Mission Since the 1893 World Columbian Exposition our organization has aimed...

A rare job opportunity for Invertebrate Zoology: fieldmuseum.hrmdirect.com/employment/j...

22.07.2025 20:33 โ€” ๐Ÿ‘ 32    ๐Ÿ” 49    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3
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BEHOLD! One of Earth's greatest lineages of life: the lil wiggle arm guys, Meteora.

These single-celled critters, originally found in deep-sea sediments, are SO DIFFERENT from other lifeforms on Earth that they're likely in their own kingdom (as in, the Animal Kingdom, the Plant Kingdom etc). ๐Ÿงช๐ŸŒฟ

10.07.2025 20:06 โ€” ๐Ÿ‘ 1437    ๐Ÿ” 441    ๐Ÿ’ฌ 39    ๐Ÿ“Œ 56
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Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution The jellyfish embryonic body axis is globally coordinated by conserved planar cell polarity (PCP) mechanisms and oriented by localised Wnt3 in two steps, highlighting PCPโ€™s role in animal axis evoluti...

Tsuyo's cool paper on Wnt3 being both a canonical and a PCP Wnt in Clytia is out doi.org/10.7554/eLif... Congratulations to everyone involved! @biodev-vlfr.bsky.social

14.07.2025 09:51 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I don't know... Depends on the context in which you have been cited. Imagine a sentence like "Prof. Moran's ridiculous claims that..." ๐Ÿ˜œ

12.07.2025 17:11 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congratulations!

28.06.2025 12:17 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks, you are very kind. We'll keep trying.

28.06.2025 11:47 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congratulations ๐ŸŽ‰

28.06.2025 11:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Uri does really cool stuff in Hydractinia

20.06.2025 17:14 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks, Uli!

17.06.2025 14:03 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thank you!

14.06.2025 13:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks, Uri!

14.06.2025 12:52 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks, Yehu!

14.06.2025 05:44 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This long, difficult, but super cool project was funded by the @fwf-at.bsky.social, and led to David winning his own ESPRIT grant! Thanks!

13.06.2025 20:35 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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