Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...

Great news and a highly anticipated article. Not a word about the immunosuppression received??? Just a mention in supplemental material (standard steroid-free IS, islet transplantation protocol by the Clinical Islet Transplantation Consortium).
www.nejm.org/doi/full/10....

Health Outcome Preferences and Trade-Offs Among Older Adults With Advanced CKD: A Discrete Choice Experiment Decision making for the treatment of kidney failure in older adults, should incorporate patient preferences. This discrete choice experiment (DCE) aimed to identify the health outcome preferences of o...

Very interesting article about the different preferences and perceptions of older patients regarding their health and increasing age.
Health Outcome Preferences and Trade-Offs Among Older Adults With Advanced CKD - American Journal of Kidney Diseases www.ajkd.org/article/S027...

The neurobiology of thirst and salt appetite Thirst and salt appetite are critical for maintaining fluid balance. In this review, Grove and Knight discuss how fluid imbalances are sensed at a molecular level and how these signals converge on bra...

Beatiful review of basic cellular and molecular mechanisms for sensing imbalances in blood osmolality, volume, and sodium content
The neurobiology of thirst and salt appetite: Neuron www.cell.com/neuron/fullt...

The Serendipitous Dance between Life and Death | NEJM As her father awaits an organ for his third transplantation, a surgical resident retrieves a kidney from a fellow hockey fan, recognizing at a deep, personal level the value of his gift of life.

Transplantation is a story of serendipity, of lives intertwined in ways both seen and unseen.
The Serendipitous Dance between Life and Death | New England Journal of Medicine www.nejm.org/doi/full/10....

Unmet Educational and Psychosocial Support Needs After... : Transplantation An abstract is unavailable.

A necessary wake-up call about an everyday reality in all kidney transplant programs
Unmet Educational and Psychosocial Support Needs After Graft Loss: A Call for Clarity and Compassion. journals.lww.com/transplantjo...

Survival of Transplanted Allogeneic Beta Cells with No Immunosuppression | NEJM The need to suppress a patient’s immune system after the transplantation of allogeneic cells is associated with wide-ranging side effects. We report the outcomes of transplantation of genetically m...

An impressive leap forward in the field of transplantation. I'm eagerly awaiting a whole organ modification. @senefrologia.bsky.social @edoardomelilli.bsky.social
Survival of Transplanted Allogeneic Beta Cells with No Immunosuppression | New England Journal of Medicine www.nejm.org/doi/full/10....

YouTube video by NEJM Group Human Papillomavirus and Cancer | NEJM

Clear, direct, understandable, i love it
www.youtube.com/watch?v=NukU...

Aquí os dejamos una pincelada del proyecto COMPARTE-TR
Súmate! @senefrologia.bsky.social @auxiliadoramaz2.bsky.social @pepasolerr.bsky.social

Frontiers Publishing Partnerships | Frailty Prevalence and Characterization Among Kidney Transplant Candidates in Spain: A Multicenter Study Frailty is a frequent condition among kidney transplant candidates (KTc) that confers poor outcomes after transplantation. We aimed to establish frailty prev...

Happy to share our collaborative work in Spain highlighting frailty prevalence among KT candidates
#frailty #kidneytransplant

url7417.frontierspartnerships.org/ls/click?upn...

The shocking hit film about overworked nurses that’s causing alarm across Europe A Swiss film about a nurse pushed to her limits one night is being praised for the picture it paints of treacherously underfunded healthcare. The director talks about the ‘heart-pounding’ story that i...

looking forward to seeing it, I'm afraid it won't be a fiction film but rather a story of everyday reality...
www.theguardian.com/film/2025/ju...

Post from The Guardian - YouTube Gaza: ‘Clean it out then bring in something good’ ► https://youtu.be/43oZ0yUDG8E “No one knows what will come to replace the international system that is cur...

youtube.com/post/Ugkxi3X...

¿Quieres formar parte de una nueva edición del #CursoTXMir2025 #TrasplanteEnAcción?
🫵🫵¡ABRIMOS INSCRIPCIONES! senefro.org/modules.php?...
Curso dirigido a socios MIR4 que quieran formarse en Trasplante Renal 👏
@alexgutierrezd.bsky.social
@martacrespo.bsky.social
@mjoseperezsaez.bsky.social

Fantástica iniciativa de nuestra compañeras del equipo de Nefrología del Hospital San Juan de Dios @senefrologia.bsky.social

Major Trials in the use of ASIs targeting difficult-to-control hypertension #NephJC

The End Kidney Deaths Act Risks Irreversible Harm to Organ Donation This Viewpoint explores the possible negative effects of the End Kidney Deaths Act on organ donation and transplant and offers strategies on how to narrow the gap between organ demand and supply.

"... a fundamental change in the ethical framework of the law will be difficult to reverse, and the unintended harms to altruism and transplantation as a noncommercial process ... are likely to be irreversible" @senefrologia.bsky.social @edoardomelilli.bsky.social
jamanetwork.com/journals/jam...

Antigen quantity is responsible for the discrepancy between phenotype and single antigen beads for the detection of HLA-DQ antibody: potential clinical implications De novo donor-specific HLA-DQ antibodies detected by single antigen beads (SAB) are significantly associated with chronic antibody-mediated rejection …

Really interesting "the common clinical practice of using the phenotype antigen beads as a screening assay, reflexing to SAB testing only when positive, may inadvertently fail to detect DQ-specific antibodies"
www.sciencedirect.com/science/arti...

THE ECONOMIC VALUE OF A TRANSPLANT NEPHROLOGIST: THE CASE FOR IMPROVING COMPENSATION MODELS This article examines the economic value of transplant nephrologists and the need for adequate compensation. Kidney transplantation is a health and li…

Uau!!! wise words "Kidney transplantation is a health and lifespan-extending procedure that relies on the expertise of transplant nephrologists" 💪👏👏 @senefrologia.bsky.social @edoardomelilli.bsky.social
www.sciencedirect.com/science/arti...

Unmet Questions About Frailty in Kidney Transplant... : Transplantation tion with transplant outcomes. Being prefrail significantly impacts both graft and patient survival, often beginning with just 1 Fried criterion. Rather than viewing frailty as a categorical state, it...

Excellent work and an essential guide 👍. With the changes in our population of kidney transplant recipients, the urgent need to improve the evaluation and treatment of frailty is becoming more evident every day. @senefrologia.bsky.social @mjoseperezsaez.bsky.social
journals.lww.com/transplantjo...

x.com/supermariajo...

One-Time and As-Needed Blood Pressure Medication and Adverse Outcomes in VA Hospitals This cohort study evaluates the risk for acute kidney injury and other adverse effects from as-needed and 1-time blood pressure medications in hospitalized veterans.

Asymptomatic BP elevations in the hospital are commonly treated with as-needed BP medications, and this could be associated with increased AKI risk. jamanetwork.com/journals/jam...

Check out the best of the best on the #AJKDBlog:

Top Ten AJKDBlog Posts of 2024!

https://bit.ly/3WyYnwz (FREE)

A paradigm shift? This interesting article shows a complex relationship between GFR, NT-proBNP and CV risk in patients with HF-pEF and CKD, and call into question proposals for higher NT-proBNP references ranges in people with CKD. @senefrologia.bsky.social www.jacc.org/doi/10.1016/...

Recommendations of the Spanish Society of Nephrology for the management of mineral and bone metabolism disorders in patients with chronic kidney disease: 2021 (SEN-MM) | Nefrología As in 2011, when the Spanish Society of Nephrology (SEN) published the Spanish

www.revistanefrologia.com/en-recommend... @senefrologia.bsky.social

A difficult question. I try to use bisphosphonates post-transplant asap after a densitometry showing osteoporosis, but also in case of osteopenia, always with PTH > 150 pg/ml. Dr. Vicens Torregrosa is our guru to guide our practice in this field. @torreandfriends @hospitalclinic.bsky.social

📖 This weekend don't miss our @kidneyint.bsky.social #ISNFridaySelection: Targeted gene therapy for rare genetic kidney diseases www.kidney-internati...

How rich is too rich? Where should society draw the line on extreme wealth? A fresh account sets out the logic and suggests how to redress inequality.

When the top 1% of people hold as much wealth as the bottom 90%, as in the US today, is it time to take drastic action? Limiting the accumulation of wealth would make societies better overall
How rich is too rich? www.nature.com/articles/d41...

What to Know About Gaza’s Humanitarian Crisis Amid Cease-Fire Push Human rights organizations and residents describe the situation in the enclave as getting more desperate. Here is a closer look.

#stopgenocide
As Hopes Rise for Gaza Cease-Fire, Conditions There Have Worsened
www.nytimes.com/2024/12/28/w...

Dialysis Facility Staffing Ratios and Kidney Transplant Access Among Adolescents and Young Adults This cohort study aims to determine whether patient to nurse or patient to social worker staff ratios are associated with access to kidney transplant for adolescents and young adults.

Sufficient staffing at dialysis centers associated with access to waiting lists and kidney transplants in older adults (Patzer RE, AJT 2014), young, and adolescents @senefrologia.bsky.social @SETrasplante @mjoseperezsaez.bsky.social @ONT_esp #acerca
jamanetwork.com/journals/jam...