Steffen Scholpp's Avatar

Steffen Scholpp

@scholpplab.bsky.social

I am a cell and developmental biologist at the Living Systems Institute (LSI) in Exeter. We work on spreading Wnt signals and characterising cytonemes in zebrafish embryos, human neurons, and cancer using high-res imaging and mathematical modelling.

2,295 Followers  |  2,070 Following  |  126 Posts  |  Joined: 13.11.2024  |  1.9915

Latest posts by scholpplab.bsky.social on Bluesky

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Team BBQ yesterday: sun, sizzle, and seriously good food!
But also bittersweet as we said goodbye (for now) to two fab members 😒. Lucy is off on maternity leave to grow a tiny scientist. Eloise is swapping pipettes for passport stamps. We’ll miss them both-but remember, our lab door is always open!

30.07.2025 08:20 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Huge congratulations to our brilliant graduates: one newly minted PhD, a sharp MSc, and two stellar BScs! You all looked majestic in your gowns β€” a well-earned symbol of your hard work, late nights, and scientific curiosity. Serious achievements, bright futures. @lsiexeter.bsky.social @exeter.ac.uk

23.07.2025 08:18 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Power presentation of Bertram about the beauty of cryo EM at the #LSIOpenDay. @lsiexeter.bsky.social

20.06.2025 13:08 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Time is running out to present your latest #Zebrafish research at ZFUK25 tinyurl.com/mw7r3nbn in Exeter. This is your chance to share your work, connect with the community, and contribute to cutting-edge discussions. The deadline for abstract submission is rapidly approaching: 30th June 2025!

17.06.2025 15:21 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Thrilled to announce a seminar featuring Prof. Hilary Ashe, a leading Cell & Developmental Biologist from @UoM_BioSci! Discover her lab's latest findings on spatiotemporal gene expression & cell communication in #Drosophila @lsiexeter.bsky.social

11.06.2025 09:55 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Carer's Awards, funded by the Genetics Society, are available to support 3 participants of the First UK Zebrafish Meeting with caring responsibilities. @gensocuk.bsky.social More info at exeter.ac.uk/ukzfmeeting

10.06.2025 06:45 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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Excellent presentation of the function of cytonemes in neural crest specification from Gemma Sutton GW4 Imaging workshop @lsiexeter.bsky.social @gw4alliance.bsky.social Cytoneme biology rocks!

09.06.2025 13:03 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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My next stop is CRUK Scotland in Glasgow. Thanks to Owen Sansom @cruk-si.bsky.social for hosting me. The @wntuk.bsky.social community is just awesomeβ€”great people, excellent research!

05.06.2025 20:51 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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I had an excellent visit to the @roslininstitute.bsky.social. They do amazing developmental biology research. Thanks to Joe Rainger for hosting me!

05.06.2025 08:10 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Award details | Funding and scholarships for students | University of Exeter

Are you an UK-based student and still looking for a PhD post in Life Sciences starting in autumn? Join the @lsiexeter.bsky.social - we have been awarded a few extra scholarships from the University. So, be quick and apply! www.exeter.ac.uk/study/fundin...

03.06.2025 14:32 β€” πŸ‘ 4    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

@scholpplab.bsky.social (Prime editing/ Nickase- & Nuclease-based
editors)
https://www.biorxiv.org/content/10.1101/2025.04.23.650248v1

@leanneiannucci.bsky.social & @katwrog.bsky.social (Optogenetics/ FGF/ BMP/ Nodal)
https://www.biorxiv.org/content/10.1101/2025.04.17.649426v1

(33/36)

26.05.2025 12:15 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Award details | Funding and scholarships for students | University of Exeter

πŸ“’ Interested? Apply now to join us! Application and eligibility details in the link.
πŸ”— www.exeter.ac.uk/study/fundin...
Deadline in 1 week.
Feel free to share this with anyone who might be interested πŸ™Œ #PhD #Planarians #StemCells #Evolution

01.06.2025 17:02 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

🧬 Project 2, with @scholpplab.bsky.social , Magda Strauss and @kylewedgwood.bsky.social :

How do planarians know what to regrow after cut?πŸ”ͺ

We will explore how signals guide regeneration, telling stem cells where to go and what to become.

We’ll use scRNA-seq, combined with imaging and modelling.

01.06.2025 17:02 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

And it ends today!

15.05.2025 17:11 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Early bird registration ends tomorrow! We already have a large number of registrations, and we are pleased to announce that the Genetics Society @gensocuk.bsky.social is now an official sponsor of the First ZF UK Meeting! Be quick and register today: www.exeter.ac.uk/research/ins...

14.05.2025 10:31 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 2
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It's time for a new @skircle.bsky.social ; skircle.me

07.05.2025 13:01 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Excellent development - a push for outstanding research in Europe!

07.05.2025 09:24 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Don't miss the First UK Zebrafish Meeting @lsiexeter.bsky.social in Exeter, sponsored by @brukercorporation.bsky.social @brukerspatial.bsky.social al.bsky.social! 🐠 Join us Sept 10 - 12. Early bird registration closes soon! Secure your spot. www.exeter.ac.uk/research/ins...

07.05.2025 09:20 β€” πŸ‘ 12    πŸ” 16    πŸ’¬ 0    πŸ“Œ 2
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We're excited to announce that Tecniplast www.tecniplast.it/uk/index.html will be our first Platinum Sponsor for the first UK Zebrafish Meeting @lsiexeter.bsky.social. You want to present your work (talk or poster)? Early-bird registration deadline is 15/5/. Don't delay! #Zebrafish #ECR #PhD

28.04.2025 08:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It was a great pleasure to meet @droutledge.bsky.social @lsiexeter.bsky.social. Seeing former lab members thrive is always enjoyable, and I look forward to further follow your career. Keep up the good work!

25.04.2025 15:05 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ˜‚

25.04.2025 05:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Optimised genome editing for precise DNA insertion and substitution using Prime Editors in zebrafish CRISPR/Cas9-mediated genome editing has rapidly become a popular tool for studying gene functions and generating genetically modified organisms. However, using this system, stochastic integration of r...

We've successfully applied Prime Editing in zebrafish for precise genome engineering. Our work compares nickase- and nuclease-based editors for substitutions and insertions, achieving heritable modifications without donor DNA. #CRISPR @zebrafishrock.bsky.social www.biorxiv.org/content/10.1...

24.04.2025 13:04 β€” πŸ‘ 29    πŸ” 3    πŸ’¬ 0    πŸ“Œ 2
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We are happy to announce that @biologists.bsky.social will sponsor the first UK Zebrafish Meeting @lsiexeter.bsky.social. Are you a PhD student/ECR who wants to present your work? Talk or poster? πŸ‘ Deadline for the early bird registration is 15/5/. So, be quick! www.exeter.ac.uk/research/ins....

24.04.2025 08:12 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1

#EZRC 30,000 mutant, transgenic, and WT lines, lab training and fish courses!!!

23.04.2025 19:40 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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We are happy to announce that The Company of Biologists will sponsor the first UK Zebrafish Meeting @lsiexeter.bsky.social . Are you a PhD student / ECR who wants to present your work as a talk or on a poster? πŸ‘ The deadline for the early bird registration is 15/5/. So, be quick! lnkd.in/eqQH_pCW .

24.04.2025 08:07 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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The LSI Exeter invites you to join the first UK Zebrafish Meeting, 10/ - 12/9/ @lsiexeter.bsky.social. We are looking for motivated PhD students/ECRs to present their work - as talks and posters. www.exeter.ac.uk/research/ins... . The deadline for the early bird registration is 15/5/. So, be quick!

14.04.2025 12:03 β€” πŸ‘ 13    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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a cartoon drawing of a sun wearing sunglasses on a blue background ALT: a cartoon drawing of a sun wearing sunglasses on a blue background

Grant proposal submitted! Yes! www.youtube.com/watch?v=xUNq...

08.04.2025 13:41 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Excellent inaugural presentation by Prof Stefano Pagliara. Thanks for the engaging talk on antimicrobial resistance! @exeter.ac.uk @lsiexeter.bsky.social

14.03.2025 18:17 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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2025 Brain Prize honors pair of cancer neuroscientists Michelle Monje and Frank Winkler share the $1.4 million award for their discovery of synapses between brain cancer cells and neurons.

And here is the link to the announcement: www.thetransmitter.org/community/20... well deserved, Michelle and Frank!

06.03.2025 10:08 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

The workshop was organised by Tom Kornberg @ucsfcancer.bsky.social , Isabel Guerrero @cbm-csic-uam.bsky.social and myself @lsiexeter.bsky.social. Do you remember. @labogden.bsky.social and @jpvincentlab.bsky.social πŸ€“

06.03.2025 10:07 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

@scholpplab is following 20 prominent accounts