Sunny X. Tang, M.D.

‘There Will Always Only Be One Jane Goodall’

I'm saddened this morning by the death of Jane Goodall. Growing up as a little girl in the 90's, she was one of two women scientists (+Marie Curie) who had a real presence as role models. I feel very grateful that now, there are so many more.
www.nytimes.com/2025/10/01/s...

Congrats to Aarush Mehta from our lab on his first first-author publication! He started working with us as a high school student and is now a senior at
@stonybrooku.bsky.social. Thanks to coauthors:
Amir Nikzad, Yan Cong, Sunghye Cho, Sameer Pradhan
4/4

A negative relationship between Happiness and Thought Disturbance and a positive relationship between Anger and Hostile Suspiciousness were replicated across samples... 3/4

A negative relationship between Dominance and Anxious Depression symptoms and a positive relationship between Surprise and Hostile Suspiciousness were replicated across timepoints.... 2/4

Glad to share our new article out in
Cognitive Neuropsychiatry! We assessed relationships between symptoms and sentiment in speech during picture descriptions from people with psychosis across 2 cohorts and 2 timepoints... 1/4

doi.org/10.1080/1354...

Very honored for our work (with Julianna Olah) to be featured by @bbrfoundation.bsky.social! We showed that a brief speech sample could provide meaningful signal informing on psychosis-related disorders. Original publication in Translational Psychiatry.
bbrfoundation.org/content/5-mi...

Super stoked to share that we received the #NOA for our R01!!! We will be using speech and language markers to develop personalized, adaptive markers for #psychosis. Very grateful for the support from the NIMH.

🔍 By analyzing both linguistic and paralinguistic speech characteristics, our approach demonstrated robust disorder-specific learning across multiple groups, including those with sub-clinical psychotic experiences & major depressive disorder. 📊 #PrecisionMedicine 3/3

The machine learning model achieved 86% accuracy distinguishing conditions on the schizophrenia-bipolar spectrum using speech features. 2/3

Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech - Translational Psychiatry Translational Psychiatry - Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech

🚨 New findings from a study led by Juliana Olah! Our recent study highlights the potential of 5-minute remote speech assessments to accurately diagnose complex mental health conditions, including schizophrenia, bipolar disorder, and MDD. 🧠💬 1/3 www.nature.com/articles/s41...

Check it out! Our work on using automated speech and language features for longitudinal modeling of #psychosis symptoms is featured in this podcast-style summary from
@dpn-journal.bsky.social !

Correcting the tag here ;) @dpn-journal.bsky.social. Thanks for publishing our work! What a great venue for research on digital psychiatry and neuroscience.

Many thanks to wonderful collaborators as always!! 6/6

@mspilka.bsky.social, Majnu John, @michaelbirnbaum.bsky.social, Ema Saito, @sarahberretta.bsky.social, @leilyb.bsky.social, ‪@myl1947.bsky.social‬, Anil Malhotra, Bill Simpson, John Kane @northwellhealth.bsky.social

Thought Disorder was particularly related to features describing subordinated constructions, efficient identification of picture elements, and decreased semantic distance between sentences. Negative Symptoms was related to features describing decreased speech complexity. 5/6

Examining one feature at-a-time, we can identify quite a few which predict each of the psychosis symptoms domains at a significance level that survives corrections for multiple comparisons. These relationships were largely robust to interactions with gender andrace. 4/6

A single component score representing the 357 speech and language features significantly predicted psychosis symptoms over time for all three domains. 3/6

We collected 160 sessions for 66 participants x 4 timepoints: 1) around the time of admission, 2) around discharge, 3) and 4) at 3 & 6 month follow up. The final feature set included 357 task-specific features representing a range of speech and language analyses. 2/6

Automated speech and language markers of longitudinal changes in psychosis symptoms NPP—Digital Psychiatry and Neuroscience - Automated speech and language markers of longitudinal changes in psychosis symptoms

Very excited to share our new paper available open-access via @dpn_journal! We evaluated objected features derived from automated speech and language processing as markers of #psychosis symptoms over time. 1/6

rdcu.be/erkV0

Really proud for our work at the Tang Lab to be featured on this month's issue of Science and Discovery! @northwellhealth.bsky.social
www.northwell.edu/news/insight...

Hope you can join for what will be a fantastic talk!

Hope to see everyone at our seminar next week! Note the updated zoom link this time.

I’m excited to share this paper now published in Psychological Medicine and reporting work from my postdoc with Dr. Greg Strauss at the University of Georgia, with a focus on improving our understanding of reward processing difficulties and negative symptoms.
www.cambridge.org/core/journal...

A sense of foreboding hangs over the National Institutes of Health There's widespread confusion and fear among scientists and doctors on the sprawling National Institutes of Health campus and at institutions dependent on the agency's funding.

Really appreciate this article from NPR highlighting the importance of the NIH in keeping Americans healthy and fighting our common enemies like mental illness, cancer and heart disease. The current disruptions are hurting all of us.
www.npr.org/sections/sho...

Reminder! Submit your abstracts for poster and oral presentations for our DISCOURSE Satellite Meeting by 2/14/25! forms.gle/nW5K9MGtBkqQ...

Amazing!! Congrats!!

When your mom life and your science skills intersect... and you use your academic poster template to make a science fair poster for your kindergartener...

Hey #ACNP2024! Come check out our poster using speech and language features and #MachineLearning for classification in a multi-diagnostic sample. Tuesday #84.

North Shore Therapeutics is presenting our preliminary findings suggesting that our AR prototype is promising for targeting negative symptoms in #schizophrenias! Check it out - Poster S11 #TIPS2024.

Check out our poster at #TIPS2024 describing our multimodal acoustics and NLP pipeline at the Tang Lab!

Thanks to our collaborators, especially at Indiana University where MERIT was conducted, recorded, and transcribed. Paul Lysaker, Kyle Minor, Bethany Leonhardt, Mark Liberman, Jen Vohs, & Courtney Wiesepape. #NLP conducted at the Feinstein Institutes for Medical Research, Northwell Health. 5/5