Neuroengineering

Nice work!

Gesundheit!: KI-Gehirn-Chip bei Querschnittlähmung - hier anschauen KI-Gehirn-Chip bei Querschnittlähmung: Was bringt ein in das Gehirn implantierter Chip Menschen mit Querschnittlähmung mehr an Lebensqualität und Mobilität?

My highlight of 2025: the first #microelectrode #BCI for spinal cord injury in Europe! 🦾⚡️🧠

🎥 (feature in German)
www.ardmediathek.de/video/gesund...

Long-term unsupervised recalibration of cursor-based intracortical brain–computer interfaces using a hidden Markov model - Nature Biomedical Engineering A hidden Markov model that uses probabilistic retrospective inference allows for up to one month of unsupervised recalibration in an online cursor-based intracortical brain–machine interface.

Frequent BCI recalibration due to changing neural activity mark a significant hurdle in long-term BCI engagement. Researchers at stanford now demonstrate a clever approach enabling unsupervised decoder adaptation by infering task labels and reinforcing the neural decoder

#neuroskyence

exactly, aphasia & SCI

@jacob-lab.bsky.social bringing it home for germany! Already the 2nd chronically implanted participant of the group

Selective engagement of the primate orbitofrontal cortex during value-based but not perceptual decisions A fundamental question in neuroscience is whether the brain uses specialized sub-systems for different types of decisions or relies on a unified decision-making network. The orbitofrontal cortex (OFC)...

New study challenges the idea of a unified decision network: Neuropixel recordings in primate OFC showed robust encoding during value-based choices but near-silence during perceptual decisions, even when rewards are at stake. #RewardSignals #neuroskyence www.biorxiv.org/content/10.1...

A wireless subdural-contained brain–computer interface with 65,536 electrodes and 1,024 channels - Nature Electronics A flexible micro-electrocorticography brain–computer interface that integrates a 256 × 256 array of electrodes, signal processing, data telemetry and wireless powering on a single complementary metal–...

DARPA-backed brain-computer interface just published in Nat. Electronics: Ken and colleagues present a fully implanted, 50-μm thick ECoG with 65.000 channels on a 256x256 grid. Their system wirelessly transmits power and signals to a relay-coil outside the skull

#neuroskyence #neuroAI #compneuro

Towards decoding individual words from non-invasive brain recordings - Nature Communications While deep learning has enabled the decoding of language from intracranial brain recordings, achieving this with non-invasive recordings remains an open challenge. Here the authors introduce a deep le...

Speech decoding on the basis of single words has so far been limited to intracranial recordings. Scientists demonstrated the feasibility of non-invasive language decoding using EEG and MEG, finding that more training data consistently increases model performance

#neuroskyence #compneuro #neuroAI

Non-invasive ultrasonic neuromodulation of the human nucleus accumbens impacts reward sensitivity - Nature Communications This study shows that non-invasive ultrasound to the human nucleus accumbens can modulate deep brain activity and enhance reward-guided learning, offering a potential alternative to invasive neuromodu...

Changing behavior with ultrasound 🔊🧠

Focused ultrasound is shown to reliably modulate deep brain areas such as the nucleus accumbens, comparable to DBS. Stimulation during a reinforcement learning task altered reward expectation, learning curves and task strategy

#neuroAI #neuroskyence #compneuro

Insular error network enables self-correcting intracranial brain-computer interface Error recognition is fundamental to adaptive behavior, enabling rapid compensatory action when outcomes deviate from expectations. Central to this function are neural circuits for performance monitori...

Insular neural interfaces

Cognitive error signals in the anterior insula propagate toward prefrontal cortex when a BCI fails to follow the user’s intention. Real-time integration enables a self-correcting neural interface that compensates for its own decoder misclassifications

#neuroskyence

Effects of eye closure on the spiking activity of human lateral geniculate neurons - Nature Communications The LGN is a critical stage between the retina and visual cortex, but the properties of human LGN neurons are not fully understood. Here the authors report that they closely resemble those in monkeys ...

Thalamus for vision BCIs

Scientists have recorded single neurons in the human LGN for the first time, revealing how it links the retina to visual cortex. When one eye is closed, neurons tuned to that eye reduce their activity, while neurons tuned to the open eye increase in spikerate

#neuroskyence

Shared and language-specific phonological processing in the human temporal lobe - Nature The human superior temporal gyrus processes acoustic–phonetic properties of speech regardless of whether the language is familiar to the listener, but only encodes word boundaries and language-sp...

New article in Nature showing that the superior temporal gyrus (STG) encodes language-specific features stronger when listening to the native language. Bilinguals on the other hand shared this higher-level tuning across both of their familiar languages

@changlabucsf.bsky.social #neuroskyence

Paradromics Gets FDA Approval to Trial Its Brain Implant in People The Austin-based startup will test its high-bandwidth device to help restore speech in people with extremely limited movement.

A race to the brain 🧠

Paradromics has just received FDA IDE approval to implant their micro-electrode array in human participants. The neuralink competitor will soon start recruiting patients with speech/motor impairments at UC Davis, Mass General Hospital and U Michigan

#neuroskyence

interesting work!

Human cortical dynamics of auditory word form encoding We perceive continuous speech as a series of discrete words, despite the lack of clear acoustic boundaries. The superior temporal gyrus (STG) encodes …

Human superior temporal gyrus (STG) encodes the progression of a word as it unfolds in time. The neural activity tracks relative position within the word, regardless of its length, and resets at each new word boundary.

#neuroskyence @changlabucsf.bsky.social

Neural correlates of phosphene perception in blind individuals: A step toward a bidirectional cortical visual prosthesis Visual prostheses are improved by decoding neural signals to predict and control visual perceptions in blind individuals.

Towards a bidirectional visual neuroprosthesis 👁️⚡️

Spiking activity near intracortical stimulation sites proved to accurately predict the brightness and sharpness of perception. Using these signals in real time could one day optimize the individualized experience of each phosphene

#neuroskyence

Neuralink Rival Synchron Raises $200 Million for Brain Implant Synchron Inc. raised $200 million to advance its work building brain implants that doctors can insert through blood vessels, avoiding the costly and high-risk surgeries necessary to install devices ma...

Jeff Bezos increases his bet on Synchron

The company behind the stentrode just raised $200M in Series D funding, led by Double point ventures, Bezos Expeditions and ARCH ventures. The funding will be used to develop smaller stentrodes reaching multiple brain regions 🧠

#neuroskyence

ISO/IEC 8663:2025 Information technology — Brain-computer interfaces — Vocabulary

Great to see the general public and legislators engage more and more with BCIs. There is even an ISO standard now:
www.iso.org/standard/832...

Towards a unified “brain language”?

@akist.bsky.social

Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity - Translational Psychiatry Translational Psychiatry - Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity

Treating OCD with neurotechnology

Researchers at UCSF used iEEG to map brain circuits in severe OCD, identifying the ventral capsule as bridge between the prefrontal cortex and limbic system. Multi-area DBS implantation led to rapid symptom improvement 🧠

#neuroskyence @changlabucsf.bsky.social

cool work!

Interesting !

Thalamocortical hodology to personalize electrical stimulation for focal epilepsy - Nature Communications Over 50 million people worldwide suffer from epilepsy, and many patients remain resistant to medication. Here, the authors hypothesized that targeting thalamic nuclei with precise anatomical...

DBS for epilepsy ?

Researchers demonstrated that stimulation of the thalamus helped reduce seizures by over 80%. Their approach showed a reduction in epileptiform discharges, in line with the nuclei's critical role in seizure termination

#neuroskyence #neuroAI #neuroscience

awesome work! it was only question of time until someone uses those concept cells in real-time

What a nice report! Funny to see all you guys in lab coats

nice work!

Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD | NEJM Geographic atrophy due to age-related macular degeneration (AMD) is the leading cause of irreversible blindness and affects more than 5 million persons worldwide. No therapies to restore vision in ...

Bigtime publication on retinal prosthesis

@science.xyz implanted 38 patients with macular degeneration with the PRIMA subretinal implant. Paired with camera-equipped glasses, the system improved central vision in 80% of participants, allowing them to read again

@maxhodak.bsky.social #neuroskyence

#neuroskyence

Congrats to such a nice publication!