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Jack Sanford

@jacksanfordphd.bsky.social

Postdoc in the Goncalves lab. Studying cancer cachexia and tumor secreted proteins.

292 Followers  |  784 Following  |  34 Posts  |  Joined: 24.11.2024  |  1.8806

Latest posts by jacksanfordphd.bsky.social on Bluesky

How about funding applications? Have you tried that potential application?

15.10.2025 17:26 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Also, the lack of reimbursement for dietitian visits has contributed to a lack of access to dietitians in many parts of the US

26.09.2025 13:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Also important to note that cancer is not the only disease that can result in cachexia. These symptoms also affect patients with:

Chronic kidney disease
Chronic heart failure
COPD
Severe infections
Sepsis

26.09.2025 13:48 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Today is the first cancer cachexia day. Please share to spread awareness.

For patients, these are symptoms to keep track of and let your doctor know if you are experiencing.

For medical professionals, a big hurdle is dietitian visits are not commonly reimbursed, despite benefiting patients

26.09.2025 13:44 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Authors, please upload a gene count matrix or even t-test excel sheet in your paper. I don’t want to have to download the raw counts

24.09.2025 18:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I’d really like to have the authors upload the gene count matrix for the omics experiments. Really annoying and computationally wasteful to have to reanalyze the raw counts.

24.09.2025 17:59 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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You asked for it! We delivered Quack-O-Grams to our members of Congress urging them to #ImpeachRFK, and get that Quack out of office!

There's still time for you to get in on this fluffy, feathery action: Send your own duck at zurl.co/W1ZnB and keep the momentum going! πŸ¦†

17.09.2025 21:32 β€” πŸ‘ 1014    πŸ” 357    πŸ’¬ 30    πŸ“Œ 63
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Contrasting cell count and biomass distributions by cell type:

◼️ Human cell size and count are nearly inversely related. More quantitatively, ...

🧡

13.09.2025 11:25 β€” πŸ‘ 12    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0

Very interesting β€” the low Ile mice eat almost twice at much as the other groups, but don’t really gain weight! Wondering if you looked at nutrient absorption through fecal calorimetry at all? Are they just failing to absorb the nutrients efficiently?

12.09.2025 18:10 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A brain center that controls consummatory responses The BNST brain region integrates a broad range of external and internal signals to flexibly regulate consumption, revealing a unified control over consummatory responses.

Massive study just published for the field of appetite control! Now only if we could harness it!

(Check out the video at the end)

www.cell.com/cell/fulltex...

11.09.2025 11:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Phospholipid looking like a wacky inflatable tube man

10.09.2025 11:23 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome - Nature Communications Authors report MagNet, a plasma extracellular vesicle (EV) enrichment strategy using magnetic beads. Proteomic interrogation of this plasma EV fraction enables the detection of proteins that are beyon...

The Mag-Net paper is out! We've now put 1000s of plasma samples through this protocol and we know others have too. We've used it to study dozens of diseases. Looking forward to seeing what others apply this towards. The preprint already has >39 citations. www.nature.com/articles/s41...

01.07.2025 14:01 β€” πŸ‘ 37    πŸ” 9    πŸ’¬ 1    πŸ“Œ 2

Science funding is in jeopardy. I think the average citizen would not think this is a good use of research funds, and would not see the part of the story that this work was done by a private company.

22.04.2025 01:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Great piece. I saw the original article and looked for the actual data too. Glad I wasn’t the only one.

I think another factor to consider is how bad the timing for this news blitz was. (1/2)

22.04.2025 01:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Incredible! Once/year HIV prevention injection

19.03.2025 22:07 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Well said. This will not stop at Columbia.

19.03.2025 16:25 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I’ve been asking ChatGPT very specific scientific questions related to my field of study. Usually the answers are a bit shallow, but more often than not, correct and based on published articles (that it properly cites)

19.03.2025 16:10 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

If I’m reading this right, they only asked the AIs to tell them where the block of text is coming from, which is a function much better performed by search engines. This is not the same as asking chatGPT a question and it giving you a completely incorrect answer

19.03.2025 16:08 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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I made my NCAA bracket based on how much each university received in funding from the NIH last year. The NIH funds incredible, life saving research at all of these universities that we cheer for.

19.03.2025 02:45 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Really interesting findings. My interpretation: Large, high profile research groups create a survival of the fittest mentality. Those who survive do quite well, but many end up dropping out of academia

18.03.2025 16:13 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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A Bifunctional Degrader Reads Out in Phase 3

The first bifunctional protein degrader to deliver Phase III data! It seems to work, but people were definitely expecting more:

12.03.2025 18:53 β€” πŸ‘ 64    πŸ” 18    πŸ’¬ 2    πŸ“Œ 2

We need to change how we talk about the NIH funding another vaccines and autism study.

Don’t say β€œthis is settled science, we already studied this”

Talk about the opportunity cost. We are NOT going to find the next cancer causing agent because we are studying this instead

11.03.2025 12:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Eating a western diet during pregnancy is associated with ADHD and autism development in offspring.

10.03.2025 11:45 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Everyone should call their representatives at least weekly to ask what they are doing to stop the illegal funding decreases

09.03.2025 14:29 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Got my sign ready for the #StandUpForScience march in DC! Hope to see many of you out there!

06.03.2025 17:35 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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It is important at this pivotal moment to @standupforscience.bsky.social. Looking forward to sharing my thoughts on why this should be a national priority at tomorrow’s rally in SF:

05.03.2025 16:54 β€” πŸ‘ 276    πŸ” 90    πŸ’¬ 2    πŸ“Œ 4

What Hank said!

03.03.2025 18:43 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

I was lucky enough to have been one of these interns. Not only did this program give me practical experience that helped me get into a PhD program, but it was as an NIH intern that I learned that I loved science.

What a loss.

27.02.2025 23:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We have to stand up for science! Anyone who can join these rallies and believes that US science must be protected should come! @standupforscience.bsky.social

15.02.2025 19:51 β€” πŸ‘ 235    πŸ” 107    πŸ’¬ 7    πŸ“Œ 2
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STAND UP FOR SCIENCE 2025 Join us in Washington, DC or your state capitol on March 7th, 2025 to stand up for science!

Just signed up to attend the March 7th Stand up for Science march in DC. Similar marches happening at state capitals nationwide.

Now is the time to double down on science. Not cut back. Make your voice heard on March 7th.

www.standupforscience2025.org/STAND-UP-FOR...

16.02.2025 18:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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