Dave Kammeyer

PCR can’t amplify RNA that’s not on the swab, and you need ~300 copies to work reliably. The question is will there be adequate RNA in the nose if replication is inhibited in the nose. Not saying I have the answer, it’s a question.

My understanding of the protocol is that normally they only did a PCR if there was an antigen +. They also did PCR on everyone at the end. I'd expect all antigen+ to be PCR+. Do you think if the virus is replicating in the lungs but inhibited in the nose that this doesn't affect PCR performance?

My question when I saw that paper was how much of the effect is azelastine just interfering with the test? I.e. if we grant that azelastine inhibits, what if you get COVID and then squirt some up your nose, and then later swab your nose, will the inhibition make the test go negative?

Yeah this sounds awesome!

Heading up to Vancouver for NeurIPS, msg me if you want to meet up!

A lot of wisdom here. The U.S. has gotten a reputation for quitting when the going gets tough. Our adversaries see this. Demonstrating the opposite would have power.

Nutrition Science’s Most Preposterous Result: Could Ice Cream Possibly Be Good for You? Studies show a mysterious health benefit to ice cream. Scientists don’t want to talk about it.

Scientifically proven: www.theatlantic.com/magazine/arc...

I have wanted this in Twitter (and in my RSS reader) forever. Add this to your feeds list and you can see posts from posters that don't post much. So many people I follow only post when they have high S/N, but I often miss what they have to say. No more! bsky.app/profile/did:...

Ever notice how English translations of Russian technical material always use the word "Complex" instead of "System?" You notice it especially in a military context, like "The S-300 missile complex has a 60 mile range." Why does this happen?

Howdy and glad to be here! It’s awesome to see bluesky up and running!