Denis Puthier's Avatar

Denis Puthier

@denisputhier.bsky.social

Science, T-cell development, thymus, genomics, bioinformatics, reproducibility, HPC, ML, software development, E-learning and many more...

78 Followers  |  709 Following  |  2 Posts  |  Joined: 20.11.2024  |  2.0536

Latest posts by denisputhier.bsky.social on Bluesky

BREAKING: Our client Mario Guevara, an Emmy-winning journalist detained by ICE in retaliation for livestreaming law enforcement activity, will be deported tomorrow to El Salvador.

Mario and his family are being punished for his reporting. This cruelty is meant to stifle our free press.

02.10.2025 22:42 โ€” ๐Ÿ‘ 32302    ๐Ÿ” 15524    ๐Ÿ’ฌ 653    ๐Ÿ“Œ 734
Preview
Twenty Years After Katrina: What We Chose Not to Learn ##August 29, 2005 โ€” Hurricane Katrina makes landfall

We knew โ€” we knew โ€” that hotter seas meant stronger hurricanes, that warmer air meant wetter storms, that rising seas meant higher surges. We had the science. We had the evidence. And still we chose to accelerate, to subsidize fossil fuels, to silence the truth.

open.substack.com/pub/rebekahj...

22.08.2025 18:54 โ€” ๐Ÿ‘ 535    ๐Ÿ” 170    ๐Ÿ’ฌ 19    ๐Ÿ“Œ 4
Preview
Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...

Weโ€™re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social.
www.science.org/doi/10.1126/...
๐Ÿงต

22.08.2025 06:02 โ€” ๐Ÿ‘ 50    ๐Ÿ” 14    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
Preview
Beyond AlphaFold: how AI is decoding the grammar of the genome Scientists are seeking to decipher the role of non-coding DNA in the human genome, helped by a suite of artificial-intelligence tools.

"I want to vibe code the genome"

โ€”the illustrious @casey.greenelab.com

as quoted by @jperkel.bsky.social @nature.com ๐Ÿงฌ๐Ÿ–ฅ๏ธ #MLSky www.nature.com/articles/d41...

18.08.2025 21:42 โ€” ๐Ÿ‘ 22    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Running testthat unit tests in parallel with Rstudio.

Running testthat unit tests in parallel with Rstudio.

In case you didn't know:

You can run your package unit tests with {testthat} in parallel with two simple steps (see testthat.r-lib.org/articles/par...):

tldr:
1. Add `Config/testthat/parallel: true` to DESCRIPTION.
2. Add `TESTTHAT_CPUS=8` to your .Renviron and restart R.

#rstats

18.08.2025 07:24 โ€” ๐Ÿ‘ 44    ๐Ÿ” 18    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Post image

Single-cell multitargets and mRNA sequencing enable the simultaneous profiling of transcriptome and up to six histone modifications in individual cells
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

06.08.2025 18:51 โ€” ๐Ÿ‘ 10    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
UMich cancels doctoral epidemiology program admissions for 2026 The University of Michigan School of Public Health will not admit a 2025-2026 admissions cycle cohort to its PhD in Epidemiologic Sciences program.

The University of Michiganโ€™s Department of Epidemiology, one of the best IMO, will not be admitting any PhD students for 2026 due to funding concerns brought about by the Trump Administration.

31.07.2025 18:45 โ€” ๐Ÿ‘ 311    ๐Ÿ” 204    ๐Ÿ’ฌ 24    ๐Ÿ“Œ 25

But damn, Donald, aren't you tired of lying like that all the time? Wouldn't you like to take a vacation ? Pfff...

31.07.2025 18:49 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump (Gift Article) Some cuts have been starkly visible, but the countryโ€™s medical grant-making machinery has also radically transformed outside the public eye.

New powerful article up in the New York Times on cancelled and delayed grants

www.nytimes.com/interactive/...

04.06.2025 15:00 โ€” ๐Ÿ‘ 304    ๐Ÿ” 209    ๐Ÿ’ฌ 11    ๐Ÿ“Œ 15
Video thumbnail

Inkscape plugin to rescale figures without distorting the text, and other useful features!
github.com/burghoff/Sci...

02.06.2025 12:15 โ€” ๐Ÿ‘ 152    ๐Ÿ” 46    ๐Ÿ’ฌ 6    ๐Ÿ“Œ 3
Post image

Last night, Russia unleashed ballistic missiles and hundreds of drones on a European capital. Today? The world barely blinks. Western media push it off the headlines, treating it as distant. But silence isnโ€™t neutral โ€” it enables aggression. Indifference has a price, and Ukraine pays it.

25.05.2025 06:11 โ€” ๐Ÿ‘ 222    ๐Ÿ” 114    ๐Ÿ’ฌ 6    ๐Ÿ“Œ 4
Video thumbnail

If you love your library, listen upโ€ฆ

15.04.2025 01:45 โ€” ๐Ÿ‘ 13389    ๐Ÿ” 4561    ๐Ÿ’ฌ 180    ๐Ÿ“Œ 226
Post image

My "tax the rich" keychain model for 3D printing on Maker World just hit another download milestone!

Public domain for your use.
makerworld.com/models/1132253

I also sell them on Etsy.
amandaroosart.etsy.com/listing/1884...

07.04.2025 20:36 โ€” ๐Ÿ‘ 9    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image 08.04.2025 02:05 โ€” ๐Ÿ‘ 423    ๐Ÿ” 175    ๐Ÿ’ฌ 35    ๐Ÿ“Œ 9

#STOPtheSAVEact

07.04.2025 12:11 โ€” ๐Ÿ‘ 218    ๐Ÿ” 99    ๐Ÿ’ฌ 12    ๐Ÿ“Œ 4

Leave FB. Nothing good here.

07.04.2025 17:34 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image 04.04.2025 15:08 โ€” ๐Ÿ‘ 1321    ๐Ÿ” 298    ๐Ÿ’ฌ 45    ๐Ÿ“Œ 10
Preview
National Security Agency chief ousted after far-right activist urged his removal Gen. Timothy Haugh was fired Thursday as director of the powerful wiretapping and cyberespionage service, according to U.S. officials.

The head of the nationโ€™s (and worldโ€™s) premiere SIGINT agency was fire on the whim of far-right conspiracist Laura Loomer:

04.04.2025 15:42 โ€” ๐Ÿ‘ 281    ๐Ÿ” 71    ๐Ÿ’ฌ 15    ๐Ÿ“Œ 2
Post image

I've uncovered the full tariff equation

03.04.2025 22:52 โ€” ๐Ÿ‘ 106    ๐Ÿ” 14    ๐Ÿ’ฌ 8    ๐Ÿ“Œ 1

Kseniia Petrova, a Russian scientist at Harvard Medical School, was detained at Logan Airport after returning from France and sent to an ICE detention in Louisiana, The Insider reports.

A big critic of Putin and the war in Ukraine, she may now be deported to Russia.

27.03.2025 20:53 โ€” ๐Ÿ‘ 7904    ๐Ÿ” 4491    ๐Ÿ’ฌ 426    ๐Ÿ“Œ 947

The below walks you through how to delete your DNA data from 23andMe before it goes bankrupt.

24.03.2025 03:27 โ€” ๐Ÿ‘ 852    ๐Ÿ” 291    ๐Ÿ’ฌ 11    ๐Ÿ“Œ 8
Preview
Attorney General Bonta Urgently Issues Consumer Alert for 23andMe Customers Californians have the right to direct the company to delete their genetic data OAKLAND โ€” California Attorney General Rob Bonta today issued a consumer alert to customers of 23andMe, a genetic testing ...

Your DNA is for sale.

This is the danger of all personal data. As a commodity, it is always at risk of being sold. oag.ca.gov/news/press-r...

24.03.2025 02:57 โ€” ๐Ÿ‘ 60    ๐Ÿ” 27    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 7
Post image

Trumpโ€™s Special Envoy Steve Witkoff assures us that none of these nightly attacks are actually happening because the Kremlin assured him that they are not taking place and โ€œI trust Putin is acting in good faith.โ€

20.03.2025 10:00 โ€” ๐Ÿ‘ 2498    ๐Ÿ” 753    ๐Ÿ’ฌ 228    ๐Ÿ“Œ 50
Map research practices survey

Reseaerchers please consider taking part in this survey about research practices undertaking by my colleague @dominiquemakowski.bsky.social limesurvey-lettres.sorbonne-universite.fr/index.php/51...

20.03.2025 10:29 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Post image

๐Ÿ’ก Saviez-vous que les maladies rares ne sont pas si rares ? ๐Ÿค”
Mรชme si une maladie est dรฉfinie comme rare lorsqu'elle affecte moins de 5 personnes sur 10 000, l'ensemble touche environ 3 millions de personnes en France, souvent des enfants.

20.03.2025 10:56 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Video thumbnail

๐Ÿ“ฃ" #Washington has become the court of Neron" says #ClaudeMalhuret
#Senat #Paris ๐Ÿ‡ซ๐Ÿ‡ท๐Ÿ‡ช๐Ÿ‡บ

youtube.com/watch?v=G-lh...

05.03.2025 09:57 โ€” ๐Ÿ‘ 82    ๐Ÿ” 36    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3
Stand up for science poster featuring event details. Stand up for science is happening on March 7th in DC and nationwide. Find more information and other ways to get involved at www.standupforscience2025.org.

Stand up for science poster featuring event details. Stand up for science is happening on March 7th in DC and nationwide. Find more information and other ways to get involved at www.standupforscience2025.org.

Itโ€™s time to #standupforscience2025 - Weโ€™re making our voice heard about the importance of the American science ecosystem, and want you to join us.

More information at www.standupforscience2025.org

#scienceforall #sciencenotsilence

16.02.2025 15:06 โ€” ๐Ÿ‘ 57    ๐Ÿ” 42    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 4
Post image

More bad news due to the #Trump #NIH war for the #LifeScienceTools companies in #biotech: Monday trading shows Illumina $ILMN shedding another -6%, and @10xgenomics.bsky.social $TXG which is highly tied to academic budgets is down -10-12% in today's trading. PacBio $PACB down -33% in the last 4wk.

10.02.2025 14:45 โ€” ๐Ÿ‘ 33    ๐Ÿ” 24    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
Post image

Stanford Medicine scientists have uncovered why women are more prone to autoimmune disorders. #2024Recap โญ stan.md/49xGGm2

13.12.2024 23:47 โ€” ๐Ÿ‘ 16    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@denisputhier is following 20 prominent accounts