Oncology Nurse Advisor

Mitoxantrone Hydrochloride Liposome Regimens Effective, Safe in Acute Myeloid Leukemia - Oncology Nurse Advisor A noninterventional, ambispective cohort analysis evaluated the real-world efficacy and safety of Lipo-MIT-containing regimens in the treatment of acute myeloid leukemia.

For patients with #AML, treatment regimens using mitoxantrone hydrochloride liposome therapy were considered effective and well-tolerated in a recent multicenter study.

https://bit.ly/3YeHJCC

#leusm

The Rise of Medical Influencers - Oncology Nurse Advisor Medical professionals who use social media to educate the public on health-related topics have grown in prominence.

#Medicalprofessionals who use social media to educate the public on health-related topics have grown in prominence. From @renalurologynews.bsky.social.

https://bit.ly/48ULx1V

#MedicalInfluencers #HCPs

Women in Low-Income Countries Face Treatment Delays in Early-Stage Cancer - Oncology Nurse Advisor Researchers assessed variations in patterns of care and time to initial treatment for women diagnosed with breast, cervical, or ovarian cancer in various countries.

These treatment delays can lead to more advanced stage #cancers and “suboptimal treatment,” the researchers wrote in their report. Published in @thelancet.com and @cancertherapyadv.bsky.social.

https://bit.ly/3Mdl5YN

#bcsm #gyncsm

Asynchronous Electronic Consent for Research Acceptable Among Patients With Cancer - Oncology Nurse Advisor Researchers reported on patient acceptance of an e-consent tool for asynchronous delivery of study information and for receiving consent from patients.

The use of an asynchronous e-consent process for prospectively evaluating circulating tumor DNA in patients with colorectal or #pancreaticCancer appeared acceptable among patients in a recent study.

https://bit.ly/4oCHvjC

#pancsm #gicsm

Core Competencies to Guide Education on the Use of Medical Cannabis Identified Researchers present consensus statement for core competencies to guide education for medical students on medical cannabis use. Researchers present consensus statement for core competencies to guide education for medical students on medical cannabis use.

Researchers developed a consensus statement to address core competencies to guide educating medical students on the use of #medicalCannabis. Published in @jamanetworkopen.com and @oncologynurseadv.bsky.social.

Read more here: ➡️ https://bit.ly/3MihDvV

Absolute Lymphocyte Count May Help Monitor Neurologic Events Following Cilta-Cel Therapy in RRMM - Oncology Nurse Advisor A retrospective study investigated the association of biomarkers pre- and post-cilta cel infusion with neurocognitive TEAEs and cranial nerve palsy in pts with RRMM.

Measuring certain biomarkers, including ALC, within the first 2 weeks of administering cilta-cel, a CAR T-cell therapy, may help identify patients with R/R #multipleMyeloma who are at higher risk of developing neurologic AEs.

https://bit.ly/3M9wFnJ

#JADPRO25

Optimizing Oncology Nursing Work Environment Improves Patient Care, Workflow - Oncology Nurse Advisor A scoping review identified key factors that ensure an optimal nursing work environment that supports nurses and quality patient care.

A holistic approach ensures that the work environment of #oncologynurses is optimized to provide quality care, including leadership programs, adequate staffing, fair allocation of resources, and a culture of open communication.

https://bit.ly/446C9FS

#OncNurse

MonumenTAL-1: Talquetamab Shows Durable Responses, Tolerable Safety at 36-Month Follow Up in RRMM - Oncology Nurse Advisor Researchers presented efficacy and ongoing safety data from MonumenTAL-1, a phase 1/2 study assessing talquetamab in patients with multiple myeloma.

Researchers characterized economic and clinical outcomes for patients treated with pemigatinib for #cholangiocarcinoma, based on whether they had ever received a diagnosis of #cancer of unknown primary.

https://bit.ly/49IdE5A

MonumenTAL-1: Talquetamab Shows Durable Responses, Tolerable Safety at 36-Month Follow Up in RRMM - Oncology Nurse Advisor Researchers presented efficacy and ongoing safety data from MonumenTAL-1, a phase 1/2 study assessing talquetamab in patients with multiple myeloma.

Patients with R/R #multipleMyeloma treated with talquetamab, an anti-GPRC5D bispecific antibody, continue to show deep, durable responses with tolerable safety at extended follow up of 30-38 months. Presented at #JADPRO25, from @cancertherapyadv.bsky.social.

https://bit.ly/49IdE5A

Direct-to-Patient Intervention Increases Lung Cancer Screening Completion - Oncology Nurse Advisor Researchers explored whether a direct-to-patient digital intervention could increase the number of lung cancer screening CTs among patients in 2 US health systems.

#Lungcancer screening uptake increased with a direct-to-patient digital health intervention. Published in @jama.com.

https://bit.ly/3XgBTQP

#lcsm #LungCancerAwarenessMonth #LCAM

Consistent Physical Activity Reduces Risk of Digestive System Cancers, Research Suggests - Oncology Nurse Advisor Alongside reducing body mass index, “physical activity may have systematic anticancer effect, such as improving insulin sensitivity, reducing hyperinsulinemia, lowering systemic inflammation, and enhancing immune function,” researchers reported.

#PhysicalActivity, particularly at a consistent level in line with guideline recommendations, significantly reduces both risk of and mortality from #digestiveSystemCancers. Published in @jamaoncology.com and @cancertherapyadv.bsky.social.

https://bit.ly/4ogfKNq

Patients With CML Living in LMICs May Reach High TFR Rates - Oncology Nurse Advisor Researchers evaluated long-term outcomes among patients with CML living in LMICs who received imatinib through financial assistance from the Max Foundation.

Treatment-free relapse is a feasible target for patients with #chronicMyeloidLeukemia living in low- and middle-income countries. Presented at #ESMO25, from @hematologyadvisor.bsky.social.

https://bit.ly/4ppEsMq

#CML #leusm

Avelumab Does Not Meaningfully Prolong Survival in Advanced Penile Cancer - Oncology Nurse Advisor Immune checkpoint inhibitors have shown efficacy in other HPV-related cancers, so a phase 2 trial tested the anti-PDL-1 antibody avelumab in patients with locally advanced or metastatic penile cancer with or without previous platinum-based chemotherapy.

A subset of patients with refractory advanced #penilecancer may respond to the immune checkpoint inhibitor avelumab, but how to identify these patients is unclear. From @renalurologynews.bsky.social.

https://bit.ly/43PJkC8

#ESMO25

Survival Prediction Model for Patients With Symptomatic Spinal Metastasis - Oncology Nurse Advisor Researchers reported on a prediction model developed to determine which patients with spinal metastases were likely to benefit from surgery.

Researchers developed a model to predict survival in patients with symptomatic #spinalMetastasis.

https://bit.ly/4rAGc7w

#spineMets

Researchers Explore Exercise, Exerkines as Next-Generation Radioprotectors - Oncology Nurse Advisor Exerkines, the molecular signals released through physical exertion, may be protective against radiation toxicities for patients with prostate cancer.

#Exerkines, the molecular signals released through physical exertion, may be protective against radiation toxicities for patients with #prostatecancer.

https://bit.ly/4ilZXv5

#pcsm

Emerging FcRN Blockade May Transform Management of FNAIT Intravenous immunoglobulin remains the standard of care for preventing thrombocytopenia and intracranial hemorrhage in FNAIT.

#Nipocalimab, a monoclonal antibody that inhibits the neonatal FcRN, has shown early therapeutic potential in FNAIT, a rare antibody-mediated disorder of #pregnancy. Published in @rarediseaseadvisor.bsky.social.

https://bit.ly/4i7aoTc

Survival in Early Breast Cancer Without pCR Improved With Adjuvant Chemotherapy - Oncology Nurse Advisor Researchers sought to determine whether survival outcomes for patients with early breast cancer was better with NACT or ACT when pCR was not achieved.

Patients with #breastcancer who did not achieve a pCR had better survival with adjuvant chemotherapy than with neoadjuvant chemotherapy.

https://bit.ly/49utroi

#bcsm

The Benefits of Ecotherapy: A Path to Healing for Those Facing a Cancer Diagnosis - Oncology Nurse Advisor An oncology social worker describes 3 nature-focused strategies — forest bathing, horticultural therapy, and animal-assisted therapy — that can help patients with cancer.

An #oncology social worker describes 3 nature-focused strategies — forest bathing, horticultural therapy, and animal-assisted therapy — that can help patients with #cancer.

https://bit.ly/44d5oXt

#CancerCare #ecotherapy

Neurologic PNS Screening Uptake in Patients With SCLC Low in US - Oncology Nurse Advisor Updated NCCN SCLC guidelines recommend testing patients with suspected PNS; however, researchers found screening uptake in the US is low.

Screening for neurologic paraneoplastic syndromes among patients with #SCLC remains low in the United States. Presented at #JADPRO25.

https://bit.ly/3LA6juD

#lcsm #LungCancerAwarenessMonth #LCAM

Interventions for Symptom Clusters May be More Effective in Newly Diagnosed MM Researchers suggest that tailoring interventions to symptom clusters and chemotherapy course may be best management strategy. Researchers suggest that tailoring interventions to symptom clusters and chemotherapy course may be best management strategy.

A better understanding of the symptom clusters experienced by patients with #multipleMyeloma can help nurses develop interventions that are targeted to reducing those symptoms and can reduce the patient’s overall symptom burden. From @oncologynurseadv.bsky.social.

https://bit.ly/49NDJQt

Sustainability Planning Strengthens Patient Navigation Programs - Oncology Nurse Advisor An overview is presented of the PNSAT, a tool for measuring the value of a navigation program from organizational context to community engagement.

SustainabilityPlanning markedly enhances the longevity and effectiveness of patient navigation programs. From #AONN2025

https://bit.ly/488Cv0X

#cancerCare

Glofitamab May Improve Outcomes in Patients With Relapsed or Refractory DLBCL - Oncology Nurse Advisor Researchers sought to determine whether glofitamab would induce responses in real-world cases of relapsed or refractory DLBCL.

Glofitamab may induce a complete response rate in 27% of real-world cases of R/R #DLBCL. Published in @ash.hematology.org journal @bloodjournals.hematology.org and @hematologyadvisor.bsky.social.

https://bit.ly/3WQaW6k

#lymsm #lymphoma

Adjuvant Radiotherapy Improves Locoregional Recurrence in High-Risk MIBC - Oncology Nurse Advisor In patients with locally advanced muscle-invasive bladder cancer who have undergone radical cystectomy and chemotherapy, adjuvant radiotherapy improves survival outcomes compared to observation only.

In patients with high-risk #MIBC, the 2-year locoregional failure-free survival rate was 87.1% with radiotherapy and 76.0% with observation. From @cancertherapyadv.bsky.social.

https://bit.ly/499ZqtR

#blcsm #bladdercancer

A One-Tenth Dose of Pembrolizumab Increases Complete Response in TNBC - Oncology Nurse Advisor “Low-dose pembrolizumab increased complete pathological response when added to dose-dense taxane backbone in patients with stage II to III triple-negative breast cancer,” said Atul Batra, MD.

In triple-negative #breastcancer, pembrolizumab at a tenth of the current standard dose, plus chemotherapy, increased pathologic pCR compared to chemotherapy alone. Presented at #ESMO25, covered by @cancertherapyadv.bsky.social.

https://bit.ly/4hUF1vb

#TNBC #bcsm

Few LGBTQ+ Cancer Survivors Receive Tailored Care Plans    - Oncology Nurse Advisor A cross-sectional study evaluated if the mode of sexual orientation and gender identification disclosure was associated with receiving clinical resources tailored to LGBTQ+ cancer survivors.

Few LGBTQ+ cancer survivors received tailored survivorship care plans and other specialized resources even though their SOGI was known to the care team. Published in @jamanetworkopen.com and @cancertherapyadv.bsky.social.

https://bit.ly/4r1bV1s

#LGBTQCancer #LGBTOnc

Analysis Links Cognitive Traits With Risk of Alcohol Use Disorder - Oncology Nurse Advisor A cohort study of more than 573,000 men identified cognitive traits that may be associated with greater risk of alcohol use disorder.

A recent study identified cognitive traits that may be associated with greater risk of #alcohol use disorder but also highlighted context-dependent features associated with this risk. From @jamapsychiatry.com.

https://bit.ly/4nQelwW

#AUD

Interventions for Symptom Clusters May be More Effective in Newly Diagnosed MM - Oncology Nurse Advisor Researchers suggest that tailoring interventions to symptom clusters and chemotherapy course may be best management strategy.

Patients with newly diagnosed #multipleMyeloma experience a high symptom burden before and after chemotherapy. Precise management of symptoms at multiple stages of treatment are essential.

https://bit.ly/4qFPyyc

#myeloma

MRD-Guided Anti-CD20 Retreatment May Delay CLL Relapse - Oncology Nurse Advisor Time to next treatment ranged from 0 months to 15.8 years, with a median of 2.3 years.

MRD-guided retreatment with anti-CD20 antibodies effectively lowers MRD levels and delays clinical relapse in patients with high-risk #CLL. Published in @bloodjournals.hematology.org and @rarediseaseadvisor.bsky.social.

https://bit.ly/4hSzzJ9

#leusm #lymsm

Adding Nimotuzumab to Chemoradiotherapy Does Not Improve Survival in HNSCC - Oncology Nurse Advisor “latinum-based chemoradiotherapy is a hard combo to beat,” said N. Gopalakrishna Iyer, MBBS, PhD, noting that the researchers were “quite surprised” by the overall survival achieved in the control arm, given the real-world setting of the trial.

Adding nimotuzumab to post-surgery adjuvant cisplatin-based chemoradiotherapy does not improve survival outcomes in patients with #HNSCC. Presented at #ESMO25.

https://bit.ly/47oCYMb

#hncsm #headandneckcancer

Electroacupuncture Accelerates Urinary Continence Return After Radical Prostatectomy - Oncology Nurse Advisor Electrical acupuncture stimulation therapy has been shown to work on other kinds of urinary incontinence, so investigators trialed the noninvasive method for continence recovery after radical prostatectomy.

Electroacupuncture to the Ciliao, Zhongliao, and Xialiao acupoints significantly accelerates time to urinary continence after radical prostatectomy for #prostatecancer, a new study finds.

https://bit.ly/4hI1yLF

#pcsm #gucsm