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Hasibe Tuncay

@tuncayhasibe.bsky.social

DREAMing meiosis, transcriptional regulation of meiosis #Arabidopsis PhD @schnittger-lab.bsky.social #meiosis4ever

54 Followers  |  116 Following  |  4 Posts  |  Joined: 30.04.2025  |  1.7451

Latest posts by tuncayhasibe.bsky.social on Bluesky

The recombination frequency (cM/Mb) along chromosome 4 of A. thaliana (female meiosis). 

In full hybrids (grey), where polymorphism is distributed all along chromosomes, most crossovers occur in the regions surrounding the Centromere (Cen), and very few at chromosome ends (Tel: telomeres). 

In lines where polymorphism is restricted to chromosome ends (purple), the local recombination rate increases drastically, at the expense of the non-polymorphic regions (yellow).

The recombination frequency (cM/Mb) along chromosome 4 of A. thaliana (female meiosis). In full hybrids (grey), where polymorphism is distributed all along chromosomes, most crossovers occur in the regions surrounding the Centromere (Cen), and very few at chromosome ends (Tel: telomeres). In lines where polymorphism is restricted to chromosome ends (purple), the local recombination rate increases drastically, at the expense of the non-polymorphic regions (yellow).

๐Ÿšจ First pre-print from my team !!

TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !

01.10.2025 08:31 โ€” ๐Ÿ‘ 51    ๐Ÿ” 19    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 5

How do plants control the genes needed for successful sexual reproduction? Our new work uncovers the DREAM complex as a crucial regulator of meiotic recombination in Arabidopsis. Without DREAM, plants are sterileโ€”key recombination genes like MER3 are switched off...

05.11.2025 15:28 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

A wonderful collaboration between our team and Benhamedโ€™s team at the Institute of Plant Sciences, Paris-Saclay. Grateful to work together with these amazing scientists! ๐Ÿ™Œ

14.11.2025 13:28 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

โ€ข Several key meiotic genes are directly regulated by the DREAM complex, revealing its central role in coordinating the meiotic program.
Given the conserved role of DREAM from plants to animals, weโ€™re excited to deepen understanding of how meiosis is regulated throughout multicellular life.

14.11.2025 13:28 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Here are some highlights:
โ€ข DREAM activates MER3 transcription, and mutants show CO formation defects.
โ€ข Restoring MER3 in the mutant background partially rescues these recombination defects.

14.11.2025 13:14 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thrilled to share our new bioRxiv preprint! ๐ŸŒฑ ๐Ÿ’ซ
We uncover how the plant DREAM complex directly regulates meiotic recombination in Arabidopsis.
So happy to finally share this piece of my PhD work!

14.11.2025 13:08 โ€” ๐Ÿ‘ 10    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Happy to share the first story from my postdoc in @schnittger-lab.bsky.social
We studied TITAN9, a Csm1-like protein in Arabidopsis.
Even though I now work with soil, chromosome segregation and meiosis still have a special place in my heart.
#meiosis4eva #meiosis #chromosomesegregation

03.08.2025 11:10 โ€” ๐Ÿ‘ 5    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
MAYosis 2025

We have a complete program !

meiosis.cornell.edu/mayosis2025/...

The #Mayosis25 seminar series will open with a tribute to Scott Hawley by @jeffsekelsky.bsky.social.

Congrats to all the selected speakers and we look forward to hearing about your fantastic science !

#Meiosis4ever

07.04.2025 08:54 โ€” ๐Ÿ‘ 7    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

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