Taghon Lab

🚨 Job alert!
The Taghon lab (Ghent University 🇧🇪) is looking for a Postdoctoral Researcher in molecular & computational immunology.
Join us to explore immune cell development in the human thymus using single-cell & spatial omics.🧬
🔗 More info here: tinyurl.com/joinTTlab
#ScienceCareers #PostdocJobs

De waanzinnige ambitie om 37.200 miljard cellen in ons lichaam in kaart te brengen Meer dan 3.000 wetenschappers bouwen volop aan een atlas van elke cel in ons lichaam. Die moet de weg wijzen naar nieuwe medische doorbraken. Zoals in een labo in Gent, waar ze met een kunstmatig orga...

Last weekend our research collaboration with @taghonlab.bsky.social at @uzgent.be, in the context of the @humancellatlas.org, was extensively covered in this nice article in @tijd.be. @viblifesciences.bsky.social

Our research on human γδ T cells is in collaboration with the lab of David Vermijlen @ulbruxelles.bsky.social
u-cri.ulb.be/index.php?ac...
In this context, he is looking for a postdoc with experience in molecular biology. Apply now to become part of the team! 👇
euraxess.ec.europa.eu/jobs/306959

Contact us for more information: taghonlab.ugent.be

Please spread the word!
@forum-gd.bsky.social

📣 We're hiring!
Are you:
- Looking for a PhD or postdoc position?
- Interested in human γδ T cells?
- Curious about employing single cell and spatial technologies to study their development?
Then apply now to join our lab!
ugent.be/en/work/scie...
ugent.be/en/work/scie...

To make our fantastic CITE-seq data set of postnatal thymocytes accessible to the community, we have launched a shiny app for interactive exploration. Check it out! 👇
ccgg.ugent.be/shiny/htsa_t...
Moreover, scRNA-seq and Visium spatial data can be found at cellxgene.cziscience.com/collections/...

Thanks to everyone involved in this fantastic collaboration, including our very own @lenamboehme.bsky.social and co-authors Nadav Yayon, Veronika Kedlian & Andrea Radtke!
Also grateful for funding from @chanzuckerberg.bsky.social, the Research Foundation Flanders (FWO) and Ghent University.

The Human Cell Atlas: towards a first draft atlas Established in 2016, the Human Cell Atlas (HCA) consortium set out to create a comprehensive biological map of cells within the human body.

Also check out the rest of the #HumanCellAtlas paper collection including insightful perspective articles: nature.com/collections/...
@natureportfolio.bsky.social

We also pinpointed the age-dependent tissue niches of TEC progenitors and explored the relationship of specialised TECs with Hassall’s Corpuscles.
All in all, an incredibly useful collection of data and tools with the potential to take #thymus research a step further. 👏

Using spatial transcriptomics, high-plex protein imaging and multimodal single cell data we studied the spatial trajectories of maturing thymocytes. These turned out to be remarkably stable from early gestation onwards but showed interesting differences for the CD4/CD8 lineages.

A spatial human thymus cell atlas mapped to a continuous tissue axis - Nature A quantitative morphological framework for the human thymus reveals the establishment of the lobular cytokine network, canonical thymocyte trajectories and thymic epithelial cell distributions in...

🚨Out now in Nature: Our spatial atlas of the developing thymus nature.com/articles/s41...
Together with the labs of Sarah Teichmann, Ron Germain & John Marioni we present insights into the establishment of the thymic organ structure in pre- and postnatal life through a new spatial mapping approach.