James Olzmann

Jessalyn Ubellacker @ubellackerlab.bsky.social was honored with a FASEB Journal Early Career Researcher Award at the first FASEB Ferroptosis, Oxidative Stress, and Lipid Metabolism meeting, co-organized by James Olzmann @olzmannlab.bsky.social and Scott Dixon, to support early career researchers.

Jennifer Doudna named 2026 Priestley Medalist by the American Chemical Society.

Congrats to MCB's Jennifer Doudna @jenniferdoudna.bsky.social on receiving the 2026 ACS Priestley Medal from the @acs.org! 👏🏅
www.acs.org/pressroom/ne...

Lysosomal membrane homeostasis and its importance in physiology and disease Nature Reviews Molecular Cell Biology, Published online: 04 August 2025; doi:10.1038/s41580-025-00873-wLysosomes degrade cellular components, and their membrane is an important signalling hub. Recent insights into the mechanisms that maintain lysosomal membrane homeostasis — including the interplay between membrane damage, repair, lysophagy and lysosome biogenesis — highlight their importance in physiology, in disease and during ageing.

ICYMI: New Online! Lysosomal membrane homeostasis and its importance in physiology and disease

Protein language models reveal evolutionary constraints on synonymous codon choice Evolution has shaped the genetic code, with subtle pressures leading to preferences for some synonymous codons over others. Codons are translated at different speeds by the ribosome, imposing constrai...

This preprint from Helen Sakharova is one of the coolest things to come out of my lab: “Protein language models reveal evolutionary constraints on synonymous codon choice.” Codon choice is a big puzzle in how information is encoded in genomes, and we have a new angle. www.biorxiv.org/content/10.1...

Fourteen Visionary Scientists Named 2025 ASCB Fellows - ASCB The American Society for Cell Biology (ASCB) is proud to announce the election of 14 outstanding scientists as 2025 ASCB Fellows—a prestigious honor recognizing their exceptional contributions to cell...

I am honored to be named a 2025 ASCB Fellow! It is a privilege to be part of the ASCB community. ASCB was the first conference I attended as a grad student, and it has always been a welcoming, supportive home. Thank you for this kind recognition! ☺️
www.ascb.org/society-news...

Riboflavin metabolism shapes FSP1-driven ferroptosis resistance https://www.biorxiv.org/content/10.1101/2025.08.05.668651v1

Vitamin B2 metabolism promotes FSP1 stability to prevent ferroptosis https://www.biorxiv.org/content/10.1101/2025.08.05.668752v1

Exciting work! Congrats, Pedro and Team! :D

Riboflavin metabolism shapes FSP1-driven ferroptosis resistance Membrane protection against oxidative insults is achieved by the concerted action of glutathione peroxidase 4 (GPX4) and endogenous lipophilic antioxidants such as ubiquinone and vitamin E. Deficienci...

🚨Preprint alert 🚨

We identify riboflavin (vitamin B₂) as a key modulator of ferroptosis sensitivity via stabilizing FSP1 & recycling lipid-soluble antioxidants.

www.biorxiv.org/content/10.1....

pls check @olzmannlab.bsky.social

www.biorxiv.org/content/10.1...

#ferroptosis #FSP1 #antioxidants

Riboflavin metabolism shapes FSP1-driven ferroptosis resistance Membrane protection against oxidative insults is achieved by the concerted action of glutathione peroxidase 4 (GPX4) and endogenous lipophilic antioxidants such as ubiquinone and vitamin E. Deficienci...

Also see a new preprint from @angelifriedmann.bsky.social and colleagues that makes similar discoveries related to vitamin B2 / FSP1 stability and ferroptosis regulation: 👏🏽
www.biorxiv.org/content/10.1...

Vitamin B2 metabolism promotes FSP1 stability to prevent ferroptosis Ferroptosis, a regulated form of cell death driven by excessive lipid peroxidation, has emerged as a promising therapeutic target in cancer. Ferroptosis suppressor protein 1 (FSP1) is a critical regul...

Excited to share our new preprint, led by Kirandeep Deol! 🤩 Genetic screens uncover mechanisms regulating FSP1 abundance in cancer. Vitamin B2 metabolism promotes FSP1 stability via FAD synth / binding, further linking nutrient metabolism to ferroptosis.
www.biorxiv.org/content/10.1...

Jennifer Doudna is named 2026 Priestley Medalist The award recognizes the biochemist for discoveries on ribozyme function and CRISPR gene editing, and international science leadership

@acs.org is recognizing Jennifer A. Doudna with the Priestley Medal for her discoveries on ribozyme function, the Dicer RNase enzyme, double-stranded RNA processing, and CRISPR gene editing, along with her impactful international science leadership. cen.acs.org/people/award... #chemsky 🧪

Thanks for coming, Kat! Look forward to hearing more about your exciting research in the future!

What a wonderful meeting! Thanks to @olzmannlab.bsky.social and the whole community for being so welcoming.🙏🏻

The first FASEB Ferroptosis conference! ✔️ Thank you to my co-organizer Scott Dixon, our sponsors, and the whole #Ferroptosis community for showing up and making this such a wonderful meeting! 🤩 ❤️

Hot topic in a hot environment! #FASEB @faseborg.bsky.social #Ferroptosis meeting organized by @olzmannlab.bsky.social and Scott Dixon is the place to be!

Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social

Fantastic meeting 🤩🤩
thank you @olzmannlab.bsky.social and Scott Dixon for the organisation and for all the colleagues and trainees that showed up and made ut such a great event!
#ferroptosis #faseb #Ros

Thanks to @olzmannlab.bsky.social and Scott Dixon for organizing a wonderful meeting. The community felt close and kind, and I return rejuvenated and energized by a reminder of why I love what I do. #ferroptosis

Currently enjoying being in sunny (and WARM) Arizona for the @faseborg.bsky.social meeting on #ferroptosis. Thanks to @olzmannlab.bsky.social and Scott Dixon for the opportunity to share our work and for promoting a welcoming and inclusive environment for scientific discussion.

@olzmannlab.bsky.social and Scott Dixon kicking off the first Faseb research conference on Ferroptosis, Oxidative stress and Lipid Metabolism
#ferroptosis #celldeath

Off to a great start at our FASEB Ferroptosis conference with our first keynote talk from Brent Stockwell! 👏 #Ferroptosis25

On my way to the FASEB ferroptosis meeting - looking fwd to catch up and learn from the leaders in the field thanks @olzmannlab.bsky.social and Scott Dixon for the invitation 🤩

Woohoo! See you soon! 🎉

General Sherman in Sequoia National Park in California, the world’s largest tree! Wow! Those specks at the base are people! 🤩
Height = 274.9 feet (83.8 meters)
Diameter at the base = 36.5 feet (11.1 meters)
Estimated Age: 2,200 years

ER_2025 #endoplasmicreticulum #ER #conference Paris October 8-10 2025 Register! itbcrde.inserm.fr/index.php?page…

@olzmannlab.bsky.social @tgalli.bsky.social @demangelab.bsky.social @agostinislab.bsky.social @abdourachidthiam.bsky.social @molinarilab-er.bsky.social @hennelab.bsky.social @jdejuan-sanz.bsky.social

Glad you can make it, Pedro. See you soon!

😃😃😃😃😃😃😃
looking fwd to this!

The count down has begun! 1-week until the 1st FASEB Ferroptosis conference! Looking forward to seeing everyone at the meeting. Get excited!! 🤩
events.faseb.org/event/11797f...