Bora Gurel, MD, Ph.D

About bloody time...

Red Bull has confirmed Christian Horner has been released from his role as team principal and CEO.

He will be replaced by Laurent Mekies. #F1

Obligatory 4th of July post #July4th

This is insane. Absolutely no good can come from this.

They hate London because it is beautiful Matthew Goodwin went to that there London the other day and what he found shook him to his core.

Blistering piece from @iandunt.bsky.social on Matthew Goodwin's visit to London.

"The success of London is a point-blank, up-against-the-wall-motherfucker refutation of the right-wing populist world view."

open.substack.com/pub/iandunt/...

I am once again pitching my romantic comedy:

- two academics start dating
- discover they are each other's terrible reviewer
- hijinks ensue

Working title: Love is Double-Blind

A poster showing icons for 40 different visualization types, categorized by goal – e.g. "showing shares" or "showing flows" or "showing developments over time".

📊 There are *so* many chart types out there. Which one should you use for what kind of data and goal?

I tried to answer the question in a new blog post (and poster!): www.datawrapper.de/blog/chart-t...

Why do random images always make the nicest looking brushes 😭 #art #meme #procreate #brushes #digitalart #markiplier

YouTube video by Netflix Frankenstein | Guillermo del Toro | Official Teaser | Netflix

youtu.be/x--N03NO130?... Only Monsters Play God…

HFF cells stained for DNA ⚪, intermediate filaments 🟠, microtubules 🔴 and actin 🔵.

#FluorescenceFriday
#SciArt

I can similarly tell when the default ggplot2 palette has been used, but I don't mind it as much, I suppose 😊

The new Neil Halloran documentary on Smallpox has completely changed how I see the RFK Jr. version of the world. Neil (softly) argues that realizing that disease isn't the fault of the sick /or/ the fault of the Gods ushered in a new future where we felt the authority to care for each other.

YouTube video by Neil Halloran Defeating a Virus That Killed Half a Billion People – The Plea

Another tour de force from
@neilhalloran.bsky.social. A must watch for scientists, biologists, educators. #theplea #science #pathsky 🧪

A light blue diagram depicting the sea, with the water's surface at the top, and just below it is an outline of the Mary Rose, with the depth (12m, 40ft or 6.7 fathoms). There is a line showing the seabed, which takes a rapid dive into the vertical...

On the anniversary of the sinking of the Titanic, we thought we'd answer a question that's often asked,

"If they raised the Mary Rose, why not raise the Titanic?"

Allow our scaled diagram to explain...

Any editors who see this interested in an editorial from two NIH-funded physician researchers on the dismantling of science and public health in the US? It’s clear and compelling, if I do say so myself.

The reason this is such a big deal is that Trumpism, an ideology of pathological insecurity and bullying, requires you to submit. When you don’t submit, it calls everything about them into question, and they can’t handle that. So don’t submit. Defy the fascist scum.

FLIMngo reliably predicts fluorescence lifetimes across photon count conditions. (a) Fluorescence lifetime maps of the ground truth alongside the maps predicted by phasor plot analysis, FLI-Net, FPFLI, and FLIMngo. The ground truth fluorescence lifetime maps are identical for both low and high photon counts, as the true fluorescence lifetime value per pixel is independent of photon counts. (b) Box-and-whisker plots of the MSE scores for predicted fluorescence lifetime maps from high photon counts compared to ground truth data. (c) Box-and-whisker plots of the MSE scores for predicted fluorescence lifetime maps from low photon counts compared to ground truth data. As FPFLI performs pixel binning, the MSE scores were calculated only on pixels representing non-background regions in the ground truths. For the Box-and-whisker plots, the line indicates the median, while the box represents the interquartile range; whiskers extend to the furthest data points within 1.5 times the interquartile range and the dots show outliers44. The data consisted of 40 simulated images with high photon counts (100-2500 photons per pixel) and the same images with low photon counts (25-100 photons per pixel), respectively. Statistical significance was calculated using a Kruskal-Wallis test followed by Dunn’s multiple comparisons, where *** denotes p < 0.001, **** denotes p < 0.0001, and “n.s.” denotes non-significant differences.

Deep learning for fluorescence lifetime predictions enables high-throughput in vivo imaging

by Gabriele S. Kaminski Schierle and team:

www.biorxiv.org/content/10.1...

Hello BlueSky! This is my first post! I don’t really know the culture yet, so I will just share a cozy little animation I made recently. #japan #cozy #fox #cat #onsen #cozy

Fox and Cat, in autumn and winter, framed on a wall

Awesome, can't wait to complete the set! 🥰

Hi Jed! We bought the winter and autumn versions of Fox and Cat over the holidays, and we absolutely love them! I was wondering if the spring and summer versions were also available anywhere. Thanks!

Fellow NSA - National Security Agency veterans. Look at what’s happened at the National Cryptologic Museum. They covered up with brown paper the photos of Women in American Cryptology. All in response to President Trump’s anti-diversity executive order.

#PathSky 43M with a giant, pendulous mass of the inner thigh. The outside clinician and pathologist were concerned for WDL, but their MDM2 FISH was negative. Certainly there is nature fat with fibrous septae and an increased number of somewhat atypical stromal cells? False negative FISH?

Thalidomide would like a word...

There's a really simple test for Schrodinger's Autist:

Explain the broken social rule to the culprit. Is the person mortified and eager to follow that rule going forward? Then the problem was social skills!

Is the person defensive, accusatory, and unrepentant? The problem was NOT social skills!

If your Christianity causes you to be offended by someone asking the most powerful person in the country to be merciful towards the powerless, then you have profoundly misunderstood the teachings of Jesus Christ.

Oh, this is right up my alley, thanks!

Thank the lord for Private Eye

A horrific image of a someone who seems to have his hands tied behind his back. A big cat (the predator kind, not the overfed pet kind) has jumped up at him and is devouring his face. Blood splashes on the floor.

For Blue Monday we can't think of anything more appropriate than this charming depiction of a man getting his face eaten off by a leopard.

#MosaicMonday

Panel 1: Mark Zuckerberg stands on the stage at a Meta all-hands meeting, wearing a little chain and a shirt that says "Cool Dude." "I think our company could use more Masculine Energy," he says into a mic. In the crowd, an employee raises their hand. "Excuse me, Mr. Zuckerberg," the person asks. Panel 2: The person stands up, asking, "By "Masculine Energy," do you mean a mature definition where men in power use their relative strength to protect and uplift those less privileged?" Panel 3: The person continues, "…or a more childish definition where men in power are free to be aggressive and harm others without being held accountable?" Panel 4: Zuck stands silent for a beat. Panel 5: "You're all fired," he says.

"Masculine Energy"

we have these! they are called books