Dynamic42

The team is on route to Boston to exhibit at #SLAS26 !!!

We are stoked to finally be able to show everyone our brand new DynamicOrgan® O2-Sensor Kit. The first fully integrated organ-on-chip technology with non-invasive oxygen measurement!

Keep your eyes peeled for the big bright pink stickers!

The first fully integrated organ-on-chip technology with non-invasive oxygen measurement. The DynamicOrgan® O2-Sensor Kit, developed in collaboration with Py... Introducing the DynamicOrgan® O2-Sensor Kit

Introducing the DynamicOrgan® O2-Sensor Kit: the first OoC tech with non-invasive oxygen measurement. Developed with PyroScience, it offers real-time, contact-less oxygen detection in models like lung, gut, liver-on-chip. Learn more from Valentin here: zurl.co/uaarx

How does perfusion influence the #TME?

/ Introduction of mechanical forces that immune cells & CAFs can sense
/ Promotion of realistic immune-vascular interactions like adhesion before transmigration
/ Overcomes limitations of 2D systems where gravity alone drives cell contact

Heading to Boston for #SLAS2026? We are too! We’ll be bringing the DynamicOrgan® System, enabling immunocompetent organ-on-chip modeling, along with an exciting, first-of-its-kind product.

Working in #cancer research? You can learn more about our new Tumor Microenvironment Kit.

"Organ-on-chip allows us to research diseases for which no animal models exist" says Japhette. It can be a game changer in pandemic preparedness, helping us understand new pathogens faster and accelerate the development of cures or vaccines. #organonchip

What types of experiments can be conducted with a cancer-on-chip model?
/ Tumor–immune interactions
/ Immune cell polarization, invasion, and migration
/ Tumor angiogenesis studies
/ Drug treatment and response testing

/ Fibrotic barrier research
/ ...

Does our solution work for all cancer types?


The TME-Kit Matrix, together with our 3-channel biochip, is designed to work with various tumors. It serves as a foundation for cancer spheroids, enabling the tumor to establish its own tumor microenvironment.

#TME #cancer-on-chip

Listen to Amelie explain the tumor-on-chip model set-up using our newly launched DynamicOrgan® TME Kit in our recent webinar.

Ready to embrace the 3R principles in your research? Join our organ-on-chip & cancer model courses!

→ Basic Course: 2-day course on basics model set-up

→ Advanced Academy: 3-day course on setting up cancer models.

Register or see upcoming dates: zurl.co/Vt9wr

We’re thrilled to see the growing interest in #organonchip & surge in its adoption in labs & regulatory bodies this year. As we look ahead to 2026, we anticipate increased relevance in drug development & biomedical research and look forward to continuing to support our customers.

As we enter the festive season our Head of Liver Anne shares insights on the state of #OrganOnChip: A promising step to reduce animal models, offering advantages over standard 2D cultures. While not yet a full replacement, the future holds potential as we increase complexity.

2025 was a wild ride! 🚀
From a 3-organ intestine-liver-placenta model to tumor-on-chip breakthroughs, new kits, U.S. expansion & 16 events - we pushed #organonchip science forward!
Thanks to all partners & the #MPS community. Onward to 2026!
More here: zurl.co/uNqw4

Last week, we hosted a webinar introducing the new DynamicOrgan® TME Kit for building advanced cancer-on-chip models.

In this short clip, Tom our head of cancer, summarizes the most important aspects he talked about in the webinar.

We are grateful to have received funding from the ESF Plus & the State of Thuringia for 3 different initiatives. Including funding for our PhD student Amélie, consulting & process support for SEO/SEA optimization and help in strengthening our understanding of ISO 9001 & audits.

⏰ Final Call! Our webinar introducing the new DynamicOrgan® TME-Kit is tomorrow!
Learn how this solution saves time on model development allowing more time for research.

🗓 Date: 04.12.2025
🕓 Time: 4 PM CEST

🔗 Register here: zurl.co/RKeZy

How does the TME Kit help establish complex, 3D tumor architectures in vitro? ➡️ Our head of cancer Dr. Tom Sommermann explains.

#OrganOnChip #CancerResearch #TumorMicroenvironment #DrugDiscovery #3DCellCulture #TumorSpheroids #Microvasculature #ImmunoOncology

New Webinar! Introducing the DynamicOrgan® TME-Kit - Advanced Organ-on-Chip Solutions for Cancer Research

Learn more on how to bring your tumor model to the next level of complexity

🗓 Date: 04.12.2025
🕓 Time: 4 PM CEST

🔗 Register here: zurl.co/DhEka

DynamicOrgan® Tumor Microenvironment Kit | Dynamic42 Build the tumor microenvironment within an organ-on-chip model → Get your quote today!

Introducing the Tumor Microenvironment Kit - Build realistic 3D tumor models easily. Spend less time on model development and more on your research.

Learn more here: zurl.co/J9pxQ

#OrganOnChip #CancerResearch #TumorMicroenvironment #DrugDiscovery #3DCellCulture

Noreen had her first breakthrough with a biochip last autumn! 🌟 She infected primary lung cells with Aspergillus fumigatus & observed hyphae growing on top of cells and invasively towards the endothelial side. A truly happy moment in her research journey! 🧫✨ #organonchip

Tim had an exciting breakthrough this year! The creation of a Candida albicans infection model using our intestine-on-chip in collaboration with the Leibniz HKI. Merging #OrganOnChip, #Microbiology, and advanced image analysis.

Noreen gives insights into her work for the RUBIN alliance "ATHANA".

She is talking about the assays she uses and the model she is building together with the lung team.

Join us at #AMP2025 in Boston at booth #945!
We’ll showcase live demonstrations of our Organ-on-Chip models. 
➡️ Register for one of our limited exclusive demos to explore our technology in detail: zurl.co/D8bSu
See you in Boston!

Do read-outs for #organonchip and #2D cell culture differ?


They don't! Why? Because the samples we can take from our organ models are very similar. We can look at the supernatants, at the cells during incubation but also extract the tissue afterward for downstream analysis.

⏳ Final reminder!

Bioinsights Live30 webinar TOMORROW: Organ-on-chip modeling for PDAC drug discovery

🗓 23 Oct | 🕔 5 pm CET
Don’t miss expert insights from Dynamic42 & HHU!

🔗 Register: zurl.co/t3mCz

#Webinar #OrganOnChip #DrugDiscovery

Discover how spheroids-on-chip are transforming preclinical cancer research! 🔬

Learn about modeling the PDAC tumor microenvironment & proof-of-concept data with SAHA.

📅 23 Oct 2025 | 5 pm CET
🔗 zurl.co/l9OXG

#CancerResearch #DrugDiscovery #Bioinsights

Meet us at Scientist Vendor Discovery Day!
Get live insights into our organ-on-chip technology, a special preview of our #TME Kit and plenty of time to connect & exchange ideas!
Register now: zurl.co/0KY9k
#Scientist #organonchip #OoC #ScientistVendorDiscoveryDay

🚀 Join our Bioinsights Live30 webinar!

Organ-on-chip innovation for pancreatic cancer drug discovery
🗓 23 Oct 2025 | 🕔 5 pm CET
Speakers: Dynamic42 & Heinrich Heine University

Register here 👉 zurl.co/6lo3T

#OrganOnChip #DrugDiscovery #Webinar

We’re heading to ELRIG Drug Discovery 2025 in Liverpool on October 21–22! 🚀
Come meet us at booth #D14 where we’ll showcase our cutting-edge organ-on-chip technology.
Stop by and say hello. We’d love to connect at #ELRIGDD25!

#OrganonChip #OoC #CancerResearch

Does it always have to be a human #organonchip?

No, sometimes we also venture into different animals, such as Anne in one of her recent projects.

🚀 Breakthrough in our #cancer-on-chip model!
Tom created a vasculature that grows into tumor spheroids overcoming previous matrix degradation challenges, he achieved direct tumor vascularization.
Want to learn how? Grab a spot in our Advanced Academy for next year!