Babraham Institute

Postdoctoral Researcher (Howard Group) | John Innes Centre An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology.

VACANCY - We have an opportunity for a Postdoctoral Researcher to join the Howard Group, working to develop computational models of epigenetic dynamics in the Polycomb system.

www.jic.ac.uk/vacancies/po...

Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time

ICYM our announcement from last week: Two incredible events unite to make one unmissable opportunity!
www.eventbrite.co.uk/e/frontiers-...

NEW PUBLICATION | A research collaboration between the Rugg-Gunn lab and Lonza is moving researchers towards the ability to drive transgene expression (in CHO cells) at higher levels to improve biopharmaceuticals yields.

analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10....

🚀 Applications are open for the Bio-spark Entrepreneurial Programme!

Are you an early career researcher hoping to consider options outside the academic world? Are you looking for advice, experience or mentorship?

🗓️ Apply by 13 Oct
🔗 www.gravity.cam.ac.u...

Frontiers in Stem Cell Innovation 2026 Join leading academics and industry professionals exploring cutting-edge stem cell technologies and disease modelling for drug discovery

3 days - 2 events - 1 amazing opportunity!
Get set for two events showcasing bioscience innovation.
4-5 Feb - WORD+ 2026 event
5-6 Feb - our Frontiers in Stem Cell Innovation (FISCI) conference
📍Cambridge
Registration for FISCI is open now: www.eventbrite.co.uk/e/frontiers-...

Text reads: News - Prizes for team behind game-changing multi-omics method to decode gene regulation. Image shows Dr Yang Wang (left) and Dr Peter Rugg-Gunn (right) shown over a data analysis plot from the scMTR-seq technique.

NEWS | A new multi-omics method enabling the profiling of multiple histone modifications and gene expression in single cells, and the researchers behind it, have been recognised with two awards. Congrats to the Rugg-Gunn lab and everyone involved!

www.babraham.ac.uk/news/2025/09...

#epigenetics

YouTube video by Dementia Researcher Advise on Publishing Your Research

Publishing Your Research? Resource for early career researchers from Alzheimer's Society Retreat

Dr Johanna Jackson @imperialcollegeldn.bsky.social
Dr Simon Andrews @babrahaminst.bsky.social
Dr Christian Schnell @plosbiology.org
Cherie Nyota @alzheimerssoc.bsky.social

youtu.be/ACqKndCoM3Q?...

We've updated our first #preprint from the lab! A collaboration with @jamesbriscoe.bsky.social

🔥 now including in vivo 🐭&👤 embryo data

www.biorxiv.org/content/10.1...

Save-the-date information: New approaches to Early embryogenesis & epigenetics February 16 - 18 2026 Max Planck Institute for Molecular Genetics, Berlin, Germany

2nd Meeting on Early Embryogenesis and Epigenetics
16 - 18 Feb 2026 at MPI for Molecular Genetics, Berlin
with support by the Weizmann Institute for Science.
Early bird registration until 30 Sep - register now👇
www.molgen.mpg.de/embryo2026

Great to have this out, and such a pleasure to work together. @smguillaume.bsky.social @cristianbeccaria.bsky.social @iannaconelab.bsky.social

🔬We have a fully funded Cambridge Biosciences DTP PhD postion to study #Proteostasis and #Aging in colloboration with @jrkumita.bsky.social @Pharmacology. Details on the project ▶️https://tinyurl.com/2zhkjjhs + bbsrcdtp.lifesci.cam.ac.uk/how-apply . Please RT.

a man with a mustache wearing a black hat and a blue shirt ALT: a man with a mustache wearing a black hat and a blue shirt

This #TrainingTuesday why not check out our recently scheduled dates for the autumn term
#Bioinformatics #ComputationalBiology #ECRchat
www.bioinformatics.babraham.ac.uk/cgi-bin/publ...
@babrahaminst.bsky.social

NEW EPISODE: Reflections from last weeks International Research Culture Conference #IRCC25 at University of Warwick organised by the National Centre for Research Culture featuring guests Chandrika Nair, Alys Kay, and Dolly Coates. Find it in your podcast app or here buff.ly/tBStCUO

This shows an antibody heavy chain successfully pairing with a surrogate light chain and signalling B cell progression. In contrast a non-pairing heavy chain fails to signal, the B cell stalls, and the suboptimal V gene is replaced by an upstream V to make a pairing heavy chain and rescue the B cell.

Delighted to share that our paper solving the age-old mystery of whether and how VH-replacement shapes the antibody repertoire is in @embojournal.org
www.embopress.org/doi/full/10....
Fantastic work from Harry White, @peterch405.bsky.social @babraham-bioinf.bsky.social @babrahaminst.bsky.social

NEWS | Work just published by the Corcoran lab has described a mechanism estimated to be responsible for shaping the generation of up to half of all antibodies.

www.babraham.ac.uk/news/2025/09/institute-immunologists-new-process-antibody-diversity

@annecorcoran.bsky.social

Exciting news📣: #ProteostasisUK is hiring a network manager to help drive an ambitious, #BBSRC funded initiative connecting and expanding #Proteostasis research across the UK. Position initially for 3 years. Deadline September 28th. More info: tinyurl.com/f83rp673 & proteostasisuk.co.uk Please RT

Will you be at the @bsrageing.bsky.social ‪#BSRA2025 this week? Look out for Institute contributions:
- @martint-babraham.bsky.social: RNA binding proteins in Tregs (Friday)
- Rahul Samant: proteostasis strategies, stress resilience & senescence (Friday)
- Institute facilities showcase

Delighted to welcome Dinis Calado to Babraham. A fantastic appointment and a lovely guy! Welcome DC!

Text reads: News: Institute welcomes Dr Dinis Calado as a senior group leader in the Immunology programme. Main image (left) shows Dinis Calado. Two images on the right are 3D confocal images of mouse bone marrow showing plasma cells (antibody producing cells; in red), endomucin⁺ vasculature (green), immunoglobulin (white), and cell nuclei stained with DAPI (blue). Credit: Abdouramane Camara, Immunity & Cancer Laboratory, The Francis Crick Institute.

NEWS | We're delighted to welcome @diniscalado.bsky.social to the Institute as a senior group leader in our #immunology programme!

The Calado lab works at the interface of immunity, #cancer, and #ageing. Learn more: www.babraham.ac.uk/news/2025/09...

How discovery research and collaboration between the @mrclmb.bsky.social, University of Cambridge, Babraham Institute, and clinicians from Addenbrooke’s identified the mutation that causes a rare immune disorder (APDS) and led to a pioneering treatment giving patients "a new lease of life".

📣 Milner Seminars: Focus on spatial biology

Please join us on 25 September for the next instalment of our seminar series, with talks from Esther Baena (Owkin) and Mats Nilsson (@stockholm-uni.bsky.social and @sangerinstitute.bsky.social).

Find out more and register: ow.ly/myoT50Wu1AX

FlyCROSS 2025–26: Call for Drosophila early career scientists - the Node Do not miss this call for mentees from the Drosophila community. Scan the QR Code & fill the mentee survey ! The Fly Board is excited to announce the

Are you an early-career researcher using Drosophila in your research?

Sign up to be matched with a mentor as part of FlyCROSS 2025-26.

Apply by 1 September 2025.

thenode.biologists.com/mentees-flyc...

#Drosophila #DevelopmentalBiology #Mentor #Career #Biology #FlyCross

Good morning from @babrahaminst.bsky.social

YouTube video by BabrahamBioinf Machine Learning Examples in Biological Sciences 1: Linear Regression

ICYMI Here are the links to all of our #BitesizeBioinformatics mini series webinars on #MachineLearning in #Biology 👇

🖥️ Machine Learning Examples in Biological Sciences 1: Linear Regression youtu.be/tIfpbDWnb0c?...

More topics and useful info our website and YouTube channel too
1/5

YouTube video by BabrahamBioinf Machine Learning Examples in Biological Sciences 4: Random Forests

It's #TrainingTuesday
As well as delivering live training courses, we also have a playlist of #BitesizeBioinformatics webinars on YouTube?
Check out the latest in our miniseries on Machine Learning in Biology, from our @babrahaminst.bsky.social biostatistician youtu.be/2MYWxp0YRpY
#Bioinformatics

Last chance to register for this brilliant international #BioHackathon
8-10 Sep
£35 for 3 days, inc. team or individual coding and problem solving, refreshments, dinner and quiz!
2025.biohack.live
Join us at venues in #Cambridge #Newcastle #Antwerp

Drshika Mehtani from the lab of Hayley Sharpe ‪
@sharpe-lab.bsky.social @babrahaminst.bsky.social won our poster prize at the EMBO Workshop "Phosphatases: from basic research to translation" for her work on redox mediated substrate interactions with PTPRK.

Congratulations!

I am delighted by the award of £600,000 network grant to support the UK Proteostasis Network that @babrahaminst.bsky.social launched in 2024 with support from @phar.cam.ac.uk @mrc-tu.bsky.social Proteostasis is critical for lifelong health and to stave off disease - in humans, animals and plants

Development presents… Wednesday 13 August 16:00 BST Chair: Yuchuan Miao Image of Toshi Yamada Toshi Yamada (University of California San Francisco) ‘Synthetic organizer cells guide development via spatial and biochemical instructions’ Image of Chrysanthi-Maria (Anthie) Moysidou (Max Delbrück Center) Chrysanthi-Maria (Anthie) Moysidou (Max Delbrück Center) ‘Bioelectronics meet neuromuscular organoids: novel tools for enhancing the maturation and complexity of organoids’’ Image of Daniel Medina-Cano Daniel Medina-Cano (MSKCC) ‘A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro’ #DevPres |@dev-journal.bsky.social Thenode.biologists.com/devprev The Company of Biologists logo Development logo QR code to register

Our upcoming #DevPres webinar focusses on stem cells and organoids, with talks from Toshi Yamada (UCSF), Chrysanthi-Maria (Anthie) Moysidou (Max Delbrück Center @mdc-berlin.bsky.social) and Daniel Medina-Cano (MSKCC).

13 August 16:00 BST

Register here: us02web.zoom.us/webinar/regi...

The UK’s proteostasis capability has been bolstered by the award of a BBSRC Network Grant, which will support the development of the UK Proteostasis Network. Prof Ari Sadanandom from our Department of Biosciences is leading the plant-focused arm of the project. Read more 👉 bit.ly/4mFT359