@isscr.org.bsky.social
The ISSCR is a global, nonprofit organization that promotes excellence in stem cell science and applications to human health. www.isscr.org
New study shows distinct #TET enzyme activities guide neural stem cell fate: 5hmC enables neuronal competence, while 5fC and 5caC are essential for #glial lineage. #neurons #stemcells ow.ly/9UX850WygWT
@einsteinmededu.bsky.social @isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social
Online now! Hematopoietic #stemcell defects in #Gata2 haploinsufficiency driven by impaired DNA damage response and inflammatory signaling; disrupting self-renewal, differentiation, and genomic stability ow.ly/28kC50WygLf
@cardiffuni.bsky.social @isscr.org
New study from @pennmedicine.bsky.social! scRNA-seq of isogenic #iPSC reveal novel individual and cooperative #hematopoietic effects of #trisomy21 and #GATA1. #myelopoiesis #Downsyndrome ow.ly/fpHC50Wrrtm
@childrensphila.bsky.social @isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social
#ISSCR submitted comments on @ema.europa.euโs concept paper revising the GMP Guidelines specific to ATMPs, supporting efforts to improve clarity and proposing an alternative approach to strengthen guidance for developers. ow.ly/MBjH50Wqyy2
16.07.2025 13:52 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
Hear from Stem Cell Reports Associate Editor Martin Pera on the 6๏ธโฃ key tips to make your submission process smooth and efficient ๐ youtu.be/xH5OMEvYw2Y
@isscr.org
Recently published: Developmental cues from epicardial cells simultaneously promote cardiomyocyte proliferation and electrochemical maturation #epicardialcells ow.ly/v1LP50WlIC9
@umnpeds.bsky.social
@isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social
Online now! Progenitor neighborhoods function as transient niches to sustain olfactory #neurogenesis via Notch/Insm1a signaling. #neuralstemcell #organogenesis #developmentalbiology ow.ly/4KJa50WlHVt
@uabcdib.bsky.social @isscr.org
New review explores the shared origin of #ependymalcells & #neuralstemcells & the potential interplay among different subventricular zone cell populations. Insights into cell fate decisions will inform the therapeutic potential of ependymal cells ow.ly/v5UF50WlHLu @isscr.org
09.07.2025 19:10 โ ๐ 1 ๐ 1 ๐ฌ 0 ๐ 0
The latest podcast has dropped. Check out Ngan Huang and Soochi Kim talking about their latest publication in stem cell reports, tinyurl.com/yvm35ec7. Listen here tinyurl.com/2njkbp7k or wherever you get your podcasts.
@isscr.org @uclastemcell.bsky.social
Submit abstract here
Weโre delighted to welcome Future Science Prize 2024 winner Hongkui Deng @pku1898.bsky.social to the speaker lineup at the upcoming @CellSymposia #CSStemCells2025. Submit an abstract for a chance to join him in LA in November! http://dlvr.it/TLn6XX
07.07.2025 15:00 โ ๐ 2 ๐ 2 ๐ฌ 0 ๐ 0
New primary breast #organoid research from
@tuftsmedschool.bsky.social published in Stem Cell Reports! DDR1 regulates RUNX1-CBFฮฒ to control breast stem cell differentiation. #organogenesis
@isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social
ow.ly/hxl250WlH5o
We have a special episode out for you now, recorded live at #ISSCR2025!
Drs. Hongkui Deng and Candice Liew share the story behind their groundbreaking study transplanting CiPSC-derived islets into a patient with #Type1Diabetes.
Listen now: bit.ly/4n9c54K
#ISSCR2025 co-chaired by Prof Kathryn Cheah culminated in June with a panel session featuring members of the HK Spinal Muscular Atrophy community, highlighting the transformative power of patient advocacy, clinical expertise & gov't collaboration in improving treatment access.
19.06.2025 07:11 โ ๐ 2 ๐ 2 ๐ฌ 0 ๐ 0
1/ ๐๐งฌ Just back from Hong Kong and still buzzing from #ISSCR2025.
I had the chance to present our latest on Cancer Cores โ assembloids where tumors are fully surrounded by healthy neural tissue. Great conversations and thoughtful feedback at the poster session. ๐ง ๐งช
Two weeks ago, I had the chance to present our #KMEB labโs work ๐ฉ๐ฐ at the #ISSCR2025 Congress in Hong Kong ๐ญ๐ฐ. A truly global event ๐! Honored to share our poster on Metabolic dysregulation in bone marrow MSCs and its link to osteoporotic fragility in women. Great science, great people!
23.06.2025 09:31 โ ๐ 1 ๐ 1 ๐ฌ 0 ๐ 1Catch up with #ISSCR2025 delegates!
Our 'On the Ground' episode is out now, and features discussions with delegates about their impressions of the meeting and the most memorable research presented.
Listen now: bit.ly/45DFhL1
Still buzzing from #ISSCR2025 ๐ฅ Huge congrats to ECRs from the ASSCR community - Maria, Agustin & Sean for sharing brilliant work on brain organoids, psychiatric disorders & kidney assembloids. Their message to future speakers? โJust go for it.โ
#StemCells #ASSCR #ECRVoices #Organoids
@isscr.org
Large-scale research resource models #Alzheimers disease with high and low polygenic risk in human iPSCs. 100+ lines from patients & controls, a powerful tool to study complex AD biology. ow.ly/TeMO50WlGMv
@ukdri.ac.uk @ox.ac.uk @isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social
New study shows committed hematopoietic progenitor cells proliferate, self-renew, and can initiate myelodysplastic syndrome (MDS) in mice. #MDS #hematology #stemcells ow.ly/gvYu50WlGbX
@isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social
#VEGF overexpression rapidly mobilizes functional #bonemarrow hematopoietic #stemcells to the blood stream and alters bone marrow vascular morphology. VEGF-induced mobilization is reversible bit.ly/3GrTkZH
@isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social
Hard to fully celebrate anything these days with so much happening around the world. Still, Iโm grateful for the chance to support our stem cell community @isscr.org โฌas a new early career editor @stemcellreports.bsky.social. Looking forward to receiving your stem cell manuscripts! #stemcells
03.07.2025 17:02 โ ๐ 4 ๐ 3 ๐ฌ 0 ๐ 0
New review explores strategies to eliminate tumorigenic hPSCs, evaluates the advantages & limitations of approaches, & discusses various methods that can be used to evaluate efficacy of PSC elimination bit.ly/4k3w6qB
@isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social
As a member of the early career editorial board for @stemcellreports.bsky.social, I am excited to share that we are looking for submissions in the field of stem cell research! I invite you to submit your work for consideration. invt.io/1bxbuu2o3ek @isscr.org
02.07.2025 20:27 โ ๐ 6 ๐ 2 ๐ฌ 0 ๐ 0
Excited to join the Stem Cell Reports team as an Early Career Editor! Grateful for the opportunity to contribute to the journal alongside fantastic colleagues. I encourage you to submit your work for consideration! @isscr.org @stemcellreports.bsky.social
03.07.2025 13:06 โ ๐ 15 ๐ 3 ๐ฌ 3 ๐ 0
#ALS research on #neuroinflammation uses a 3D spinal microtissue model of C9orf72 ALS. FDA-approved drug screen IDs #sartans as inhibitors of neuroinflammation, & #telmisartan preserves motoneuron survival against C9-microglia-mediated toxicity. bit.ly/3HYZCQW
@isscr.org
Book your calendars for the 2026 ISSCR meeting in Montreal in 1 year! An exciting speaker line up!
@isscr.org
www.isscr2026.org/overview
Online now! The #R-spondin 2 (RSPO2)-RNF43/ZNRF3 axis serves as a master regulator for taste tissue homeostasis. bit.ly/4llNA2m
@isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social
#ISSCR2026 @isscr.org plenary and invited speakers have revealed! Please plan to submit an abstract and join us in Montreal! www.isscr2026.org/speakers
26.06.2025 21:32 โ ๐ 4 ๐ 2 ๐ฌ 0 ๐ 0
Online now! Promoting quality standards and reporting best practices to improve quality, reproducibility, and translatability of #stemcell models and results bit.ly/3FX0p4t
@isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social
The global stem cell community remembers the life & contributions of James Till, who passed away on May 18 at the age of 94. Alongside the late Ernest McCulloch, Dr. Till conducted pioneering research in the 1960s that proved the existence of stem cells.
www.isscr.org/isscr-news/i...
