Organization for the Study of Sex Differences (OSSD)

Sex differences in noradrenergic regulation of the medial prefrontal cortex in mice - Biology of Sex Differences Background Norepinephrine (noradrenaline; NE) is a stress signal released from the locus coeruleus (LC) into the prefrontal cortex (PFC) to govern arousal, attention, and cognition. The LC is sexually...

Did you know female brains have stronger norepinephrine projections from locus coeruleus to prefrontal cortex? BUT prefrontal neurons are less sensitive to signaling than in males! This study found sex differences in this stress and decision-making circuitry. #sabv #ossd #sexdifferences #humanhealth

Establishment of sex-specific liver transcriptomes and H3K9me3 profiles during sexual maturity: the impact of maternal obesity - Biology of Sex Differences Background The escalating prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is closely linked to rising obesity rates. Maternal obesity (MO) is associated with increased s...

A mother's diet can leave lasting epigenetic fingerprints on her offspring's liver, altering how genes are expressed, long after the young eat healthy again. These changes can disrupt metabolism sex-specifically, potentially raising lifelong risk for fatty liver disease. #sabv #ossd #sexdifferences

Impact of continuous testosterone exposure on reproductive physiology, activity, and pain-related behavior in young adult female rats Testosterone may reduce pain in cisgender women and transgender men. Rodents can provide a useful model for investigating physiological effects of hor…

Giving female rats testosterone at male-like levels helped them bounce back faster after surgery, but it didn't actually make them experience less pain. Testosterone boosted recovery, not pain resistance! #sabv #ossd #sexdifferences #humanhealth www.sciencedirect.com/science/arti...

⏰Last call for #OSSD2026 abstract submission for travel award consideration! The deadline to submit is TODAY at 11:59 pm ET. Connect with colleagues, showcase your work, and explore beautiful #Hawaii at #OSSD2026!

Submit your work here:🔗https://www.ossdweb.org/ossd-2026-abstract-details

www.ossdweb.org/ossd-2026-ab...

This just in: Deadline to submit poster abstracts and for travel award consideration has been extended to tomorrow, January 20, 2026! Submit your abstracts and join us for the 2026 Annual OSSD Meeting at the Hilton Waikoloa Village in Kona, Hawaii, May 12-16, 2026! More info below:
#OSSD #SABV

www.ossdweb.org/ossd-2026-ab...

Deadline to submit your poster abstract and consideration for a travel award is January 19, 2026! Submit abstracts for the 2026 Annual Meeting at the Hilton Waikoloa Village in Kona, Hawaii May 12-16, 2026! More info here: ossd.memberclicks.net/ossd-2026-ab...

Biological sex matters in brain aging Every cell in the body has a biological sex. The expansion of aging research to investigate female- and male-specific biology heralds a major advance …

Did you know that every cell in your body has a biological sex? Exploring how male and female cells age differently is opening the door to new ways of diagnosing and treating brain aging. #sabv #ossd #sexdifferences #humanhealth

www.sciencedirect.com/science/arti...

🚨🚨Abstract submissions are live and due in just 1 week!🚨🚨 Join us and present your science in beautiful Hawaii May 12-15! Submission deadline Jan. 19, 2026, 11:59 pm ET, details here:
www.ossdweb.org/ossd-2026-ab...

This study is a result of incredible work of Devin Rocks & crown of his PhD thesis. Thanks to @ossdcomm.bsky.social @sbn-bsky.bsky.social @sfn.org for awarding his work & the whole team for support: @luisadema.bsky.social @lailaouldibbat.bsky.social
@masako-suzuki.bsky.social @greally.bsky.social 🔥

Sexual dimorphism in the serum metabolome following acute exhaustive exercise - Biology of Sex Differences Background Sex differences in exercise metabolism have been recognized for decades, but the molecular metabolic landscape in which men and women reach standardized physiological exhaustion criteria re...

Link to paper: link.springer.com/article/10.1...

Sexual dimorphism in the serum metabolome following acute exhaustive exercise - Biology of Sex Differences Background Sex differences in exercise metabolism have been recognized for decades, but the molecular metabolic landscape in which men and women reach standardized physiological exhaustion criteria re...

Did you know even when men and women push themselves to the exact same level of exhaustion, their bodies use unique molecular strategies to process fat? Scientists found several blood molecules that move in opposite directions between sexes! #sabv #ossd #sexdifferences #humanhealth

Did you know, although women are diagnosed with Alzheimer's disease more than men, cortical thickness decline with age is greater in men, suggesting other factors than sex and age mediate this difference? www.pnas.org/doi/10.1073/... #sabv #ossd #sexdifferences #humanhealth #alzheimersdisease

Chronic intermittent alcohol yields sex‐specific disruptions in cortical‐striatal‐limbic oscillations in rats This study shows that chronic alcohol exposure leads to sex-specific disruptions in local field potentials, specifically causing changes to amygdala oscillations in females and prefrontal cortical an...

Did you know that the neural circuitry most impacted by chronic alcohol exposure is sex-specific? onlinelibrary.wiley.com/doi/10.1111/... #sabv #ossd #sexdifferences #humanhealth #memory

Inspired by Catherine Woolley’s amazing presidential lecture on sex differences at #SFN25? Check out @ossdcomm.bsky.social for a scientific community that focuses on sex differences across fields of study, and in basic and clinical research and public policy!

Inspired by Catherine Woolley’s amazing Presidential lecture on sex differences at #SFN25? Check out @ossdcomm.bsky.social for a community of scientists across fields (including basic and clinical work, and in public policy) that focus on sex differences!

Sex-specific behavioral changes in middle-aged mice - Scientific Reports Scientific Reports - Sex-specific behavioral changes in middle-aged mice

Did you know that there are sex-biased changes in several memory modalities as early as middle-age? www.nature.com/articles/s41... #sabv #ossd #sexdifferences #humanhealth #memory

Abstract deadlines for #OSSD2026!

General abstract deadline: January 19, 2026 at 11:59 PM ET

Late Breaking abstracts for poster and undergraduate attendee awards: March 13, 2026

More info: www.ossdweb.org

#OSSD #SABV #sexdifferences #humanhealth #hawaii

📢DEADLINES📢 for the 20th Annual #OSSD Annual Congress in Kona, Hawaii, May 12-15 2026!

🗓️SYMPOSIUM PROPOSALS must be in by this Friday 10th October🗓️

Info:
www.ossdweb.org/ossd-annual-...

#OSSD2026 #OSSD20thAnnualMeeting #sabv #SexDifferences #HumanHealth

Important dates for the 20th Annual #OSSD Annual Congress in Kona, Hawaii, May 12-15 2026!

For additional information:
www.ossdweb.org/ossd-annual-...

Hope to see you there!

#OSSD2026 #OSSD20thAnnualMeeting #OrganizationfortheStudyofSexDifferences #conference #sabv #SexDifferences #HumanHealth

Join us for the 20th Annual #OSSD Annual Congress in Kona, Hawaii, May 12-15 2026!

For additional information:
www.ossdweb.org/ossd-annual-...

Hope to see you there!

#OSSD2026 #OSSD20thAnnualMeeting #OrganizationfortheStudyofSexDifferences #conference #sabv #SexDifferences #HumanHealth

Important areas of investigation, with significant health disparities!

#sabv #ossd #sexdifferences #humanhealth

Is sex at birth a biological coin toss? Insights from a longitudinal and GWAS analysis Offspring sex may not be random—maternal age and genetics influence sex clustering within families.

The "choice" between all-boy and all-girl sibship is not random!

Illuminating insights into complexities of sex-associated differences in offspring sex determination!

doi.org/10.1126/sciadv.adu7402

#sabv #ossd #sexdifferences #humanhealth #sexgenetics

It was so good to see everyone in ABQ & hear about exciting science! I am sorry I had to leave early but see you next time in a gorgeous place! 🌴☀️🌊 #OSSD2025 —> #OSSD2026
@ossdcomm.bsky.social
@liisagalea.bsky.social @themorrisonlab.bsky.social @travisehodges.bsky.social @drglitterbear.bsky.social

Excited for @liisagalea.bsky.social keynote at Annual meeting of @ossdcomm.bsky.social

Really enjoyed the Women’s Health Research @ossdcomm.bsky.social pre-meeting today. Thanks to all who came to my talk & for all generous feedback I received - it means a lot! Thanks to @liisagalea.bsky.social for organizing… So good to see everyone and feel so much dedication and support for WHR! ❤️

B Penaveler Bernabe: Perinatal depression is complex - what about using the gut microbiome? @ossdcomm.bsky.social we cannot study things in isolation.

Sex differences in metabolism exists across a wide variety of outcomes. Body composition energy storage etc. @swhr.bsky.social @ossdcomm.bsky.social #OSSD25

Up next @bonniee-leee.bsky.social on how previous parity influences functional connectivity in an animal model of Alzheimer risk (hApoe4) - bonnie calls this the Parity Paradox www.biorxiv.org/content/10.1...