Aaron Fleischer

Cortical glutamatergic and GABAergic inputs support learning-driven hippocampal stability Flexibility and stability of neuronal ensembles are crucial features of brain function. Little is known about how these properties of local circuits are influenced by long-range inputs. We show, in mi...

www.science.org/doi/10.1126/...

Correct, the humans just had to inspect first for, uh, reasons…

Prettiest, derpiest, most insistent, most demanding. All synonyms 😂

I think her tummy is doing a lot better. No diarrhea anymore, which is great. We’ve had her in a donut to prevent her from getting to the abscess, though, and it’s definitely still bothering her to a degree, but less than it was, so maybe getting there?

She collects on the cheese tax as often as she can, and rightfully so 😌

Day 146. Luna would very much like to bother you for that string cheese. It’s actually hers, you bought it for her. Please return it to its rightful owner. Thank you. #UglyDogs

🚨 Today, I formally introduced articles of impeachment against Robert F. Kennedy, Jr.

RFK Jr. has turned his back on science and the safety of the American people. Michiganders cannot take another day of his chaos.

In this episode, Dr. Daisy Singla joins Dr. @liisagalea.bsky.social to discuss the SUMMIT trial, talk therapy, and how task-sharing and telemedicine can change perinatal mental health.

🎧Listen: ow.ly/UIcj50XGOaA
#WomensHealth #PerinatalMentalHealth

She’s upset about the donut, though 😂 very much not a fan of it!

She’s doing a lot better. Poop is very solid now, thanks to the treatment and diet. Now we just have to worry about the abscess and making sure that heals nicely with treatment, too

Okay, they miiiiight need to be thrown away at this point 😂

Day 145. I couldn’t find any good pictures of the pets today, but here’s a good loaf. I’ll try harder tomorrow! #UglyDogs

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www.canada.ca/en/impact-pl...

Shaft versus spine localization affects the structural plasticity of glutamatergic synapses https://www.biorxiv.org/content/10.64898/2025.12.05.692591v1

Sexual dimorphism in the serum metabolome following acute exhaustive exercise - Biology of Sex Differences Background Sex differences in exercise metabolism have been recognized for decades, but the molecular metabolic landscape in which men and women reach standardized physiological exhaustion criteria re...

Did you know even when men and women push themselves to the exact same level of exhaustion, their bodies use unique molecular strategies to process fat? Scientists found several blood molecules that move in opposite directions between sexes! #sabv #ossd #sexdifferences #humanhealth

Day 144. Luna recommends cooling off in this blistering heatwave as much as possible and in any way you can. She sure knows how to heat the heat. (Also ignore the decaying pumpkins 😂) #UglyDogs

Day 144. Luna recommends cooling off in this blistering heatwave as much as possible and in any way you can. She sure knows how to heat the heat. (Also ignore the decaying pumpkins 😂) #UglyDogs

Psilocybin rewires specific mouse cortical networks in lasting ways Neuronal activity induced by the psychedelic drug strengthens inputs from sensory brain areas and weakens cortico-cortical recurrent loops.

A single psilocybin dose in mice sparks neuronal activity that leads to long-term changes in the wiring of specific networks, according to a new study.

By @siddhantpusdekar.bsky.social
https://bit.ly/4pqcpwR

Same! I think being able to see her was good for the vet and getting an actual prognosis

Good intuition! I wasn’t expecting an abscess, so I hope what they were able to clear out will help give her some comfort. Darn bodies and health issues! I think she’s starting to feel a bit better already, though

Same. She’s a trooper, but she deserves a bit of rest and good health!

Very much so!

Yeah, I’m hopeful we’ll start seeing some good improvement soon!

We tend to think of neurons as either excitatory or inhibitory, but some neurons chemically inhibit their downstream targets while electrically exciting their neighbors. What is gained by having an inhibitory neuron excite its neighbor?

www.biorxiv.org/content/10.6...

Poor pup has to stick to donut-cone life for a bit just to make sure she doesn’t open things up on her own, but things are looking hopeful! Bonus is that she snores a little with the donut on 😂🥰

Update on Luna. Good news is that her stool is starting to solidify, and vet gave metronidazole and a fiber-heavy diet to help. Bad news is the bleeding is from an abscess, and she didn’t let them fully express it. Hopefully prescripts will help, but may need lancing later.

That’s good to hear! Yay Sahara! Fingers crossed for similar results for Luna soon too!

We got an appointment for this morning, so I’m hoping it’ll be more helpful!

Nope, that’s the first recommendation for allergy testing. We’re going into the vet in just a little bit, so I’ll bring that up and see what they think we could do! Thank you!