Frank Schnorrer

Thanks so much Vijay. I hope all is fine at your side 😊

Thanks Katja 😊

Thanks Thomas 😊

On the cover - Congrats @jeromeavellaneda.bsky.social @nunoluis.bsky.social
flies fly! @fly-eds.bsky.social www.cell.com/developmenta...

Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting

I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:

FlyBase Update – October 2025 The termination of the NIH/NHGRI FlyBase grant has placed the long-term sustainability of FlyBase at risk. However, thanks to the generous support of several key individuals and institutions, we are pleased to announce that FlyBase will remain operational through the coming year. We extend our deepest gratitude to Yukiko Yamashita, Cassandra Extavour, Hugo Bellen, Thom Kaufman, the Genetics Society of America / Drosophila Board, the Bloomington Drosophila Stock Center, an anonymous donor and the Wellcome Trust. We are especially thankful for a generous gift from Seemay Chou, Jed McCaleb, and The Navigation Fund. We also greatly appreciate the continued support from the broader Drosophila community – your donations and service fees have been vital in helping us stay afloat. Special thanks also go to Jessica Manning for her tireless administrative work at Harvard, to Ruth Lehmann, Hugo Bellen, and Paul Sternberg for advice and efforts, and to the Board of the European Drosophila Society for all their efforts. Sadly, we must also share that several long-standing FlyBase team members have recently moved on. We are immensely grateful to Susan Russo-Gelbart, Lynn Crosby, Gil dos Santos, Kris Broll, Victoria Jenkins, and TyAnna Lovato for their many years of dedicated service and contributions to FlyBase. Looking ahead, ensuring FlyBase’s sustainability beyond the next year – and successfully integrating with the Alliance – will require new funding sources. We kindly ask for your continued support: • European labs: Please consider contributing to the Cambridge, U.K. FlyBase group • U.S. and other non-European labs: Please consider contributing to the U.S. FlyBase groups • Both U.K. and U.S. FlyBase are working diligently to establish an invoicing system. We appreciate your continued patience. For more information on how to support us, please visit: Contribute to FlyBase wiki page https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase...
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila

We close the day at #25EngLife with an inspiring talk by @frankschnorrer.bsky.social Titin rules!

Read about how female muscles grow larger than male ones! and hearts too!

Females are larger than males. How? Here is one solution- they have MORE nuclei in their flight muscles and grow LARGER heart and fat body cells with MORE ribosomal mRNAs. Fun collaboration of @jeromeavellaneda.bsky.social with @soumitrakp.bsky.social & Brian Oliver www.biorxiv.org/content/10.1...

Thanks Laurent!

Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...

Thanks so much Brian 😀

Thanks Ale 😊

Thanks Julien

Thanks so much. Brian, very glad to hear that this is likely conserved. We tried to a bit in mouse but are not experts and could get convincing data in 3D.

SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...

Visualising where different genes are switched on throughout a fly

📷 @jasperjanssens.bsky.social et al @steinaerts.bsky.social
@cbdresearch.bsky.social @frankschnorrer.bsky.social
@centuri-ls.bsky.social in @elife.bsky.social

➡️ bpod.org.uk/archive/2025/5/14 with @DrJohnAnkers

Thanks Ken

The amazing tour de force of the great @lcferme.bsky.social is now out in its final form in @ScienceAdvances (not on Bluesky???). It was hard work and all the conceptual advance was her doing. Check it out: www.science.org/doi/epdf/10....

I see 😊 so nice to be together there - and nematic to crystalline applies to sarcomerogenesis too. 💡💡. Congrats Caren

Thanks Francoise

Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social
www.science.org/doi/epdf/10....

😀 looking forward to continuing our collaboration

Congrats Stefan, very cool news 😀

Epithelial biology: Holding the corners together A new study reveals that the Drosophila follicular epithelium opens its permeability barrier to allow passage of yolk to the oocyte by relaxing, not actively pulling open, cell vertices. This work res...

Great Dispatch article by @tarafinegan.bsky.social on our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social - thanks for condensing our findings so clearly and nicely!
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de

Fly group leaders in Eastern Europe, UK, France, Germany, Switzerland/Austria, please step forward. The European Fly community needs your help. #Drosophila #EDRC

💪🇺🇸🇫🇷

Spatial transcriptomics in fly brain and body. Wonderful collaboration with @steinaerts.bsky.social led by @jasperjanssens.bsky.social @pierremangeol.bsky.social Nikolai Hecker & Gabriele Partel - look at mRNA patterns in muscles and brains spatialfly.aertslab.org
elifesciences.org/reviewed-pre...

Welcome PAvel - so nice to see you there 🌞

@biancah0406.bsky.social