Delighted to present Latent Interaction Variational Inference (LIVI), a framework for trans-eQTL mapping at single-cell resolution that I developed during my PhD together with colleagues from @steglelab.bsky.social 1/n
08.02.2026 16:54 β π 22 π 11 π¬ 1 π 3
The webinar series on spatial transcriptomics analysis is now open for registration!
Join me on 18 March to learn how we at @bayraktarlab.bsky.social integrate single-cell and spatial transcriptomics to map the rules of neurological conditions.
29.01.2026 20:03 β π 3 π 2 π¬ 0 π 0
Beyond excited to share my first work with Omer's group at Sanger!
With amazing co-authors Alexander & Fani we are passionate about neurodevelopmental genetics and this work really showed us the power of uncovering new genetics with spatial transcriptomics!
π§΅π Background / motivation / key results
11.11.2025 21:00 β π 5 π 2 π¬ 0 π 0
Very proud of our paper on "scrambling-by-hopping" LADs, which was just published: www.nature.com/articles/s41.... Congrats to Lise Dauban and the rest of the team β this was a real tour-de-force!
02.09.2025 17:26 β π 58 π 24 π¬ 0 π 0
π§ Excited to share my main PhD project! We mapped the regulatory rules governing Glioblastoma plasticity using single-cell multi-omics and deep learning. This work is part of a two-paper series with @bayraktarlab.bsky.social @oliverstegle.bsky.social and @moritzmall.bsky.social, Preprint at endπ§΅π
16.05.2025 10:04 β π 78 π 29 π¬ 1 π 6
How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 new studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. multimodal cell atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic π§΅
16.05.2025 11:42 β π 73 π 31 π¬ 6 π 5
Iβm happy to share that our scCellFie manuscript is finally on bioRxiv β a project that was an amazing opportunity to return to my roots in metabolism!
We infer metabolic activity from single-cell & spatial transcriptomics π§¬
Read the pre-print hereπ
π doi.org/10.1101/2025...
15.05.2025 08:21 β π 6 π 1 π¬ 1 π 1
Our review "Predicting gene expression from DNA sequence using deep learning models" is finally out! π€
14.05.2025 15:43 β π 44 π 11 π¬ 4 π 2
Thrilled to share our new @naturecomms.bsky.social study with @sam-n-barnett.bsky.social on early vs late #COVID19 lung damage π«.
Using single-cell & histopathology-informed #SpatialTranscriptomics, we uncovered key biomarkers & immune patterns. Thanks to collaborators, UKCIC & @humancellatlas.org
12.03.2025 06:35 β π 5 π 1 π¬ 0 π 1
Another great computational method out of the Bayraktar lab!
Alexander Aivazidis has been a great colleague in our lab and it's amazing to see the capstone of his PhD is now published.
03.03.2025 13:16 β π 2 π 0 π¬ 0 π 0
Feri's fundraiser for Refuge
Help Feri Torabi raise money to support Refuge
And the talented PhD student Feri from @mhaniffa.bsky.socialβs
lab is running for Refuge:
supporting women and their children to overcome the impact of domestic abuse.
www.justgiving.com/page/feri-to...
01.03.2025 14:00 β π 2 π 0 π¬ 0 π 0
Jimmy's fundraiser for Alzheimer's Research UK
Help Jimmy Lee raise money to support Alzheimer's Research UK
Our labβs computational wizard @drjimmylee.bsky.social is supporting Alzheimerβs Research UK: www.justgiving.com/page/jimmy4a...
01.03.2025 14:00 β π 2 π 0 π¬ 1 π 0
Next weekend I will run the Cambridge half marathon with @sangerinstitute.bsky.social colleagues πββοΈ
Two amazing people are running for charities, please support them!
01.03.2025 14:00 β π 2 π 1 π¬ 1 π 1
This is really horrific. These single cell reference atlases are widely used as is to train all kinds of models! This is one of the reasons I've constantly harping about uniform reprocessing & extremely careful QC of large atlases. 1/
04.12.2024 07:06 β π 144 π 41 π¬ 9 π 4
Historicus - docent Universiteit Leiden & NIMAR
βThis will end in tearsβ - Violet Crawley
Postdoc at Biozentrum in Basel, and incoming group leader at the IMBA in Vienna.
How do single cells decide what to become? What to do? When? Where? In fact, how do humans?
https://www.oeaw.ac.at/imba/groups/daan-de-groot
Distinguished Research Professor of Sociology at the University of Amsterdam (UvA) and director of the Netherlands Institute for Advanced Study in the Humanities and Social Sciences at the Royal Netherlands Academy of Arts and Sciences (NIAS-KNAW)
#compbio & #cancer | visuals & organisation
bioinformatician @ umm | phd @ dkfz
ππ»ββοΈπ¨ πββ¬ π¦
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Delivering world-class bioinformatics training in data-driven life sciences virtually and onsite at EMBL's European Bioinformatics Institute in Hinxton, UK.
www.ebi.ac.uk/training
Historian, journalist, writer, editor.
https://www.boekenwereld.com/TT/?tt=12322_12_423305_&r=%2Fgetbook%2Fisbn%2Faddtocart%2Fisbn-9789026326547
www.hassnaebouazza.nl
http://www.cambridgeartstudio.com/ (not https yet)
https://www.flickr.com/people/bakerart/
UK artist of mature years. Gallery shows in the past but mostly just twice a year at the Cambridge Drawing Society now. Not looking for sales at the moment.
Journalist with focus on Arab world, including Palestine for @therightsforum.bsky.socialβ¬. Previously lived in Cairo, now Netherlands. Author of two books on Egypt ('Nu de wereld niet meer kijkt' en 'AlexandriΓ«').
Journalist. #VPRO. #Volkskrant. #Frontlinie. Podcast: Achter de Frontlinie.
PhD Student, MRC Biostatistics Unit
University of Cambridge
Gates Cambridge Scholar
Bioinformatics, genetics, single-cell, statistics
Australian π¦πΊ
Professor in Systems Biology & Genetics @EPFL, opinions my own; Single Cell Omics / Gene Regulation / Transcription Factor / Stem Cells / Regulatory Variation / ML / Imaging / Adipose Biology / Microfluidics
https://www.epfl.ch/labs/deplanckelab
We are the Winkler Laboratory at the UKHD and DKFZ Heidelberg
Our focus: #cancerneuroscience of #braintumors ( #glioblastoma #brainmetastases), and beyond.
We use #intravitalimaging , #calciumimaging, #preclinicalmodels and more, to tackle these diseases
Research group leader @German Cancer Research Center, reconstructing human development and disease using cell fate engineering
The Refugee Council is the nationβs refugee charity. We support refugees to rebuild their lives, integrate into communities and play a part in Britain.
Group Leader in Human Genetics, Wellcome Sanger Institute