@winklerlab.bsky.social
We are the Winkler Laboratory at the UKHD and DKFZ Heidelberg Our focus: #cancerneuroscience of #braintumors ( #glioblastoma #brainmetastases), and beyond. We use #intravitalimaging , #calciumimaging, #preclinicalmodels and more, to tackle these diseases
Coming soon: The #BrainConference on #CancerNeuroscience:
πΊοΈ Rungstedgaard (CPH,DM)
π
25-28 Aug 2026
Please join chairs @michellemonje.bsky.social & Frank Winkler and an great line up of speakers to discuss the newest findings.
Early bird registration is now open π
@fens.org #FENS #Neuroscience
βI was advised that having multiple children would detract from my scientific career. But I actually think that it has greatly benefited it.β Prof. @michellemonje.bsky.social, Neurology and Neurological Sciences at Stanford University, #BrainPrize2025.
#Neuroscience
youtu.be/f7sbSuWie5A?...
βIn the laboratory we find truth. We find something that was not known before. We hope to translate that back to patients to improve care, to improve treatments, and outcomes.β @michellemonje.bsky.social, Neurology and Neurological Sciences at Stanford University, #BrainPrize.
youtu.be/-mVeQuQfJ1E
βBasic science often gives you a hard time. There are periods, weeks, even months, sometimes years, where you are not moving forward. But in the end, the rewards are enormousβ Frank Winkler, prof. of Neuro-Oncology, Brain Prize winner 2025.
#Neuroscience #TheBrainPrize
youtu.be/7_CZz4gFyqU
How do nervous system tumours reshape neural circuits?
Join the 2nd #BrainPrize2025 webinar with @michellemonje.bsky.social and Frank Winkler moderating a panel of leading researchers.
#neuroscience #webinar
youtu.be/Lj8pYKhGqKM
Now online: the @brainprize.org #webinars on #cancerneuroscience! π§ π¬
Learn more about the #neuroscience of #braincancer, #cancer remodelling of #neuralcircuits, and #PNS #nerve regulation of #cancer from experts in the field!
π Enjoy!
Im Nachgang zum Webinar "DFG-FΓΆrderung fΓΌr #ClinicianScientists" (6. November 2025, >280 Teilnehmer*innen) π haben wir alle Informationen und auch die PrΓ€sentationsfolien auf unserer Website zusammengestellt - jetzt unter:
β‘οΈ www.dfg.de/de/foerderun...
Neurons help gliomas grow. Discover how in the first #BrainPrize2025 webinar with @michellemonje.bsky.social and Frank Winkler - pioneering insights reshaping brain cancer research.
#braincancer #neuroscience #webinar
youtu.be/k6Pgbq5IZGI?...
π’ Registration (free!) for the NCI webinar series 'Fueling Cancer Progression by the Nervous System' is open!
π§ π¬ Amongst many excellent speakers, Frank Winkler and @venkatesh-lab.bsky.social discuss #cancerneuroscience of #brainmetastasis
π
6 exciting topics are covered by leaders in the field π‘!
1/ New βfundamentalβ study shows that neuronal migration depends on blood flow in the adult mammalian brain.
elifesciences.org/articles/995...
Cover of this week's Nature showing a brain rendering Cover caption from the journal: Brain development: Our ability to process information into complex emotions, behaviours and decisions relies on the rich diversity of cell types that make up the human brain. Uncovering the molecular and cellular events that take place during brain development could reveal not only the mechanisms that give rise to this diversity but also shed light on how this process might go awry in neurodevelopmental disorders such as autism and schizophrenia. In this weekβs issue, the BRAIN Initiative Cell Atlas Network (BICAN) builds on its previous work creating atlases of cell types in the adult mouse, non-human primate (NHP) and human brains to present cell-type atlases of the developing human, mouse and NHP brains. Across a suite of papers, nine of which are published in Nature, the researchers uncover the complex programs through which cell types emerge during brain development in humans and animals, revealing both the shared and unique features of the human brain. The latest work, along with future research directions, is summed up in a Perspective article by Tomasz Nowakowski and colleagues
New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) π§ π§ͺπ¬
An amazing set of resources for all scientists working on the brain!
π§ Immersive feature:
www.nature.com/immersive/d4...
π§ Perspective:
www.nature.com/articles/s41...
Autumn in #Heidelberg. We are excited to welcome the brightest scientists in Neurooncology at the 8th Harvard Heidelberg Alliance in #Neurooncology!
@dkfz.bsky.social @uniheidelberg.bsky.social
Fantastic presentation @melinamueller.bsky.social ! We are very proud to have you in the lab and looking forward to future discoveries π€©
#UNITE-GBM #cancerneuroscience
@neurooncologyhd.bsky.social
Thank you for the amazing #CancerNeuroscience conference @helloeacr.bsky.social!
We had a great time in Bilbao @winklerlab.bsky.socialπ§ .
Itβs a wrap! What a fantastic and inspiring #EANO2025. It was great to share projects and ideas. Looking forward to Rome.
@winklerlab.bsky.social
@hlsalliance.bsky.social
@cn-hd.bsky.social
@eanoassociation.bsky.social
Very much looking forward to presenting our work on the #cancerneuroscience of #brainmetastasis in session OS10 later today #EANO2025 !
#preclinical #NeuroOncology
We want to say a huge thank you to all who attended and helped organise Cancer Neuroscience this week in Bilbao π
The next EACR conference is virtual and just around the corner - register for Patient Involvement in Cancer Research by Monday! eacr.org/conference/p...
Now online in Cancer Discovery @aacrjournals.bsky.social: Screening for Tumor Microtube-Targeting Drugs Identifies PKC Modulators as Multipotent Inhibitors of Glioblastoma Progression - by Daniel AzorΓn, Dirk Hoffmann, @winklerlab.bsky.social, and colleagues doi.org/10.1158/2159...
14.10.2025 12:00 β π 29 π 7 π¬ 1 π 0
Attending the @helloeacr.bsky.social Cancer Neuroscience meeting in Bilbao, Spain today? Check out my PhD student @austejabaleviciute.bsky.social poster in this evenings session "Targerting Microglia in Diffuse Midline Glioma - heating up the Tumour Microenvironment'
14.10.2025 10:16 β π 8 π 2 π¬ 0 π 0π£ Today is the day!! π£
The @helloeacr.bsky.social #CancerNeuroscience conference will kick off in beautiful Bilbao, Spain.
πͺπΈ π§ π€©
Itβs an excellent program π
We are looking forward to many interesting new insights and discussions! π‘
See you in a few hours! π
#cancer #neuroscience #EACRconference
Congratulations π! Very well deserved ππ€©π₯³
14.10.2025 04:55 β π 3 π 0 π¬ 1 π 0Congratulations π₯³
13.10.2025 18:49 β π 1 π 0 π¬ 1 π 0
Presenting recipients of our 2025 Stimulator Grant:
πTACTICS: Thalamocortical Assembloids and Computational Tools for Investigating Cellular Signatures in #Autism.
π§ How do autism-linked mutations disrupt early brain development? @moritzmall.bsky.social @steglelab.bsky.social
@dkfz.bsky.social
#CancerNeuroscience Online Seminar, October 21, 5-6 PM, CET.
Elizabeth Repasky, Roswell Park Comprehensive Cancer Center, Buffalo, NY - Chronic adrenergic stress and thermoregulation: critical neuro-immune interactions that promote cancer in laboratory mice.
us06web.zoom.us/meeting/regi...
The Brain Prize lecture by Larry Abbott at ECNP 2025
Come and join The Brain Prize Lecture from Larry Abbott, US, at #ECNP2025. The 2024 prize co-recipient will present work on how connectomics advance our understanding of two neural systems, as well as its implications for neurology.
Details: www.ecnp.eu/congress2025...
#TheBrainPrize #neuroscience
Thank you, @danielazorin.bsky.social and @dirkchoffmann.bsky.social,
on behalf of all of us at the Winkler Lab, for driving this project! Itβs exciting new work and the next step towards new therapeutic strategies against this horrific disease.
Thank you, @danielazorin.bsky.social and @dirkchoffmann.bsky.social,
on behalf of all of us at the Winkler Lab, for driving this project! Itβs exciting new work and the next step towards new therapeutic strategies against this horrific disease.
My main PhD project is out in #CancerDiscovery @theaacr.bsky.social
We found that PKC activators (TPPB) destroy tumor microtube networks that glioblastoma cells use to invade & resist therapy.
Huge thanks to my first co-author @dirkchoffmann.bsky.social , @winklerlab.bsky.social & all co-authors!
Very excited to see this out and happy to have contributed!
10.10.2025 07:35 β π 6 π 2 π¬ 1 π 0#Glioblastoma cells donβt just grow β they extend tumor microtubes that let them invade the brain π§ and link into multicellular networks that resist therapy β’οΈ.
We developed a strategy to inhibit these TMs β and make these cells vulnerable to therapy β οΈ.
This study is now online @Cancer Discovery
