Myofin Research Group

Happy Halloween! 🎃👻🔮 The single muscle fibres won the ”Best Group Costume” prize at @folkhalsanresearch.bsky.social 🏆

Check out our recap videos from #EMC2025 and #WMS2025 on our Instagram 📹 :

European Muscle Conference (www.instagram.com/reel/DPTJFxc...)

World Muscle Society Congress (www.instagram.com/reel/DQOT_LV...)

… whereas Tibial Muscular Dystrophy shows a more localized pattern (notably tibialis anterior and extensor digitorum longus), helping distinguish them radiologically.” (2/2)

Different Lower Limb Muscle MRI Patterns in Autosomal Dominant Titinopathies Background and Purpose Titin is critical for sarcomere structure and function, and mutations in this gene cause titinopathies, a group of neuromuscular disorders. Muscle MRI is a key tool for diagno.....

🚨Publication alert!🚨

Marco’s summary of the article:

”New multicenter MRI study shows that in autosomal dominant titinopathies, Hereditary Myopathy with Early Respiratory Failure involves broad, severe fat replacement (esp. in semitendinosus, gluteus minimus and obturator externus), … (1/2)

Thank you @worldmusclesociety.org for an amazing meeting #WMS2025 💪🔬 The Finnish team thoroughly enjoyed the science and the networking! @myofinlab.bsky.social @folkhalsanresearch.bsky.social

A few highlights from a great week at #WMS2025 in #Vienna with the @myofinlab.bsky.social team!

Congrats to Maria Francesca and Johanna for their poster prizes! 🌟
#WMS2025
@worldmusclesociety.org

Great times with the Myofin team (@myofinlab.bsky.social) at #WMS2025 In Vienna !😂

@jaakkosarparanta.bsky.social presenting in the poster highlights session! 👏
#WMS2025
@worldmusclesociety.org

So many "MyoFinns" in the #WMS2025 meeting this year! 💪🔬 Representing @myofinlab.bsky.social @folkhalsanresearch.bsky.social

Our team is excited to connect - come find us at the @worldmusclesociety.org congress. 🇦🇹 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
#WMS2025

Special thanks to Fleur, Tom, Leander, Buram and Osman for letting us tag along on their experiments! The plan is to come back next spring/summer for some real experiments. 🤩 (2/2)

During the week in between EMC and WMS, Jenni and Fanny visited the de Winter, Ottenheijm and Kirby labs at the Department of Physiology at Amsterdam UMC for an intro to single fibre mechanics and some interesting imaging techniques. 🇳🇱🔬 (1/2)

Helsinki south harbour and cathedral from the sea.

Starting my voyage towards Vienna and #WMS2025 on the Helsinki–Stockholm ferry.

Two years from today #Helsinki and #Finlandiahall will welcome #WMS2027, the annual congress of @worldmusclesociety.org. Save the date!

Greetings from the opening ceremony of the European Muscle Conference 2025! 🇳🇱 #EMC2025 #EuropeanMuscleConference

Our team is excited to connect - come find Jenni, Jaakko and Fanny at the European Muscle Conference. 🇳🇱 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
#EMC2025 #EuropeanMuscleConference

Myofin ”Summer” meeting in Nuuksio 🧬💡🌲. A couple of days filled with insightful scientific talks and interactive discussions on current and upcoming projects! On Wednesday evening it was sauna time and we grilled sausage over the fire 🧖🔥🪵.

Our team is excited to connect - come find Johanna at the Norwegian Conference for Hereditary Neuromuscular Disorders. 🇳🇴 Let’s talk science, collaboration, and future ideas! 🧬🤝💡

Registration for the @myofinlab.bsky.social - organized course, ILS144: "Genetic and genomic technologies in health care" is open. Link: tinyurl.com/43n2ydwu @folkhalsanresearch.bsky.social @helsinki.fi

When you get a feeling that someone's watching.. Our summer student making great progress with our AI analyses ❤️💪🔬 #muscleresearch #raredisease #myoblue @myofinlab.bsky.social @folkhalsanresearch.bsky.social

So many reasons to celebrate! And these guys are always up for some bubbles 🎉🥂💪🔬 @myofinlab.bsky.social @folkhalsanresearch.bsky.social

Recent #Research by Jenni Laitila of folkhalsanresearch.bsky.social‬ et al. observes that #pathogenic TNNT1 variants are associated with aberrant thin filament compliance and #myofibre hyper-contractility 🔬 🧬

🔗 Read the work here: https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP288109

Two new Academy Research Fellows and one joint Academy Project at Folkhälsan Research Center receive funding The Research Council of Finland’s Scientific Council for Biosciences, Health and the Environment has granted funding to two new Academy Research Fellows at Folkhälsan Research Center. Elina Engberg an...

Elina Engberg and Jenni Laitila are new Academy Research Fellows, and a joint project on the oral microbiome in health and disease received Academy Project Funding.
@elinaengberg.bsky.social @laitilajenni.bsky.social @myofinlab.bsky.social @fin-hit.bsky.social
research.folkhalsan.fi/news-article...

What is your favourite food?
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“As an Italian, for me pizza is the best food in the world! However, lately I've realized that also korvapuusti is not so bad...”

Three words that describe you
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“Curious, enthusiastic and a bit "weather-sensitive".” (5/5)

▫️Get to know Alessandra! 👋

Your favourite experiment/analysis to perform?
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“I like working with cells because culturing them is very stimulating and relaxing at the same time.” (4/5)

She is now spending 6 months as a visiting student at Folkhälsan, working at the generation of an in vitro model of PLIN4-related myopathy. (3/5)

She is currently a PhD student at the University of Milan and Istituto Neurologico Carlo Besta, focusing on the investigation of the pathogenetic mechanisms underlying a very rare muscular disorder. (2/5)

Meet our visiting researchers! 🧬🌍

▫️Alessandra Carnazzi (MSc), Doctoral researcher

Alessandra is originally from Italy. She pursued her master’s degree in medical biotechnology at the University of Milan. (1/5)

"In the families where inheritance was recessive, no correlation could be made between the types of variants and the severity of the disease. In contrast, all patients with large dominant deletions in NEB had milder, predominantly distal muscle weakness." (4/4)