RE: https://ecoevo.social/@marcrr/115656029348896562
Update of our preprint on detecting selection on regulatory sequences! We notably added an analysis for human, where the likelihood test per ChIPseq peak lacks power.
There is a similar problem with branch-site dN/dS tests, and a solution has [โฆ]
In support of #OpenScience, we routinely ask authors to openly share their #research #code before publication.
We are now formalizing this practice with a mandatory #CodeSharing policy and clarifying what we mean by code sharing.
Huge spectrum of views on this. At one end, visions of a living 'article of the future' with embedded data in wondrous new formats. At the other, "just a PDF".
What is most interesting to me is that someone's position on that spectrum does not correlate with how tech savvy they are. 1/n
Are #openaccess fees that some journals charge authors too high? The Chinese Academy of Sciences, the worldโs largest research institution, reportedly thinks so and plans to stop funding some, a move that could shake up #scientificpublishing. @science.org www.science.org/content/arti...
24.02.2026 23:16 โ ๐ 47 ๐ 33 ๐ฌ 2 ๐ 5
Coming up in March! Join @sortee.bsky.social for a webinar with @daxkellie.bsky.social on good, shareable, and reproducible R code - register here: events.humanitix.com/sortee-webin...
24.02.2026 23:43 โ ๐ 24 ๐ 24 ๐ฌ 0 ๐ 1
I am hiring a Postdoc (18 months contract in Montpellier, France) to study how polyploidy affects sex chromosomes in the plant Silene latifolia, using bioinformatic analyses of RNA-seq and DNA-seq data. Deadline for applications March 24th. euraxess.ec.europa.eu/jobs/412961
24.02.2026 15:57 โ ๐ 18 ๐ 36 ๐ฌ 0 ๐ 0
๐๐ฅ How is sex determined? How is it encoded in the #3Dgenome?
Read all about it in our last paper!
www.nature.com/articles/s41...
Itโs been looong but feels satisfying to see this finally out.
(With CapelLab, @dariloops.bsky.social Lab and @mamartirenom.bsky.social Lab)
๐งต๐
Have you ever wondered ๐ค... Does phenotypic variance respond to environmental perturbation? Does it have a genetic basis? Are mean and variance regulating loci exposed to different selection pressures? These and more questions are explored in our new preprint ๐ฅ
www.biorxiv.org/content/10.6...
Up to what degree of interspecific genetic distance is it possible to form viable and fertile hybrids? A strange species of paramecium breaks the record:
www.biorxiv.org/content/10.6...
We are thrilled to announce Paolo Crosetto's presentation titled "The Drain of Scientific Publishing: Why Publishing Has Become a Challenge for Science and How It Can Be Improved" in our upcoming PCI Webinar on March 19th at 4 PM (GMT+1)!! ๐คฉ
To learn more and sign up, please visit buff.ly/bxYWPCz
Mi gente latino!
Ya llegรณ ya estรก aquรญ. La primera reuniรณn de Biomoleculas antiguas en Latinoamerica patrocinada por el @official-smbe.bsky.social . Reserven la fecha y estรฉn al pendiente de las fechas importantes. Mas info en nuestra pagina web smbeperu.github.io/SMBEperu-esp/
๐งฌWe are launching STRiVE, a @eseb.bsky.social Special Topic Network on the evolutionary role of structural genomic variation.
๐๏ธStd:
29/04: Online seminar w/ L. Rieseberg
8-10/07: Kick-off in Porto
Join us: structuralvariantsstn.github.io #Evolution #Genomics #StructuralVariants #Biology #PopGen
Estรฉn el pendiente y reserven la fecha ๐คฉ๐งฌ๐ต๐ช
20.02.2026 12:59 โ ๐ 1 ๐ 3 ๐ฌ 0 ๐ 0
To add one thing: if you have the data to run both classic dN/dS tests and MK tests, choose the latter. dN/dS tests are blind to positive selection in the important, constrained proteome, while MK test will work regardless of constraint, if DFE well estimated.
#evolution #adaptation #popgen
๐บ New preprint out with John Pannell and @charlesmullon.bsky.social ! ๐บ
We show that selection broadly favours a form of plasticity for the selfing rate where individuals adjust their mating behaviour to their condition โ their overall vitality owing to their genetic background and environment. โคต๏ธ
Congratulations to everyone involved!
Below is the link to the article.
@luisapallares.bsky.social @nedabarghi.bsky.social @rachaelabay.bsky.social @ahancock.bsky.social @genmig.bsky.social @meauxjuliette.bsky.social @abepalmer.bsky.social @kjschmid.bsky.social @mpi-evolbio.bsky.social
New paper with @vsudbrack.bsky.social. Using pop gen modelling, we show that partial selfing makes selection on tandem repeats more efficient, reducing the associated load across different scenarios. Thanks to @snsf.ch @dee-unil.bsky.social @fbm-unil.bsky.social !
www.nature.com/articles/s41...
If you are a scientist, working on biology, wondering where to submit your manuscript given the current issues with the academic publishing system, check out wheretopublish.github.io!
We did this thinking change is possible. Letโs make it happen!
Treponemal diseases might have been with us much longer than previously thought! In our recent study, we used ancient DNA to reconstruct a 5,500-year-old ๐๐ณ๐ฆ๐ฑ๐ฐ๐ฏ๐ฆ๐ฎ๐ข ๐ฑ๐ข๐ญ๐ญ๐ช๐ฅ๐ถ๐ฎ genome, revealing a previously unknown divergent subspecies.
You can check it out here:
www.science.org/doi/10.1126/...
The next step in a great scientific adventure led by @mbrasovives.bsky.social on amphioxus evolution: population genomics of a species with 3% heterozygosity! Read the thread and the preprint ๐
20.01.2026 12:34 โ ๐ 3 ๐ 2 ๐ฌ 0 ๐ 0Amphioxus strikes again! Check out our new preprint led by the wonderful @mbrasovives.bsky.social ! Thread and link below.
20.01.2026 10:52 โ ๐ 3 ๐ 1 ๐ฌ 0 ๐ 0
1/7 ๐งฌ New preprint!
What is it like to have one of the highest genomic diversities among metazoans?
๐ www.biorxiv.org/content/10.6...
We've got ISSUES. Literally.
We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do?
arxiv.org/abs/2601.07563
A ๐งต 1/n
No deal with #SpringerNature
Switzerland has been without an agreement since 1.1.2026. Consequently, the SNSF is pausing funding for #OpenAccess articles in these journals.
This joint measure with the ๐จ๐ญ higher education institutions strengthens our negotiating position.
โน๏ธ Info : sohub.io/a8rh
Should funders mandate where grantees can publish?
Probably not.
But funders could mandate where grantees cannot publish.
๐งต
1/11
Well done Swissuniversities! @snsf.ch et al. once again leading the charge (see previous special issue announcement).
Funders and institutes hold the cards. If they don't pay the profiteers, we researchers will just adapt.
We don't need Nature. Nature needs us.
#SciPub #ResearchIntegrity
๐ #swissuniversities didn't reach a deal with #SpringerNature, so it is recommending ๐จ๐ญresearchers to not publish nor review for any journal of that publisher.
Uni funding was cut? rethink where your APCs went:
โ
reinvestment in science from society journals
OR
โ to โฌ2M revenue for Springer?
1/๐งต
Influence a change in behaviour where authors are encouraged by their universities to no longer publish with an entire suite of journals since the APCs aren't covered.
Authors find new, non-Springer journals, life goes on.
Yes, we should have stopped playing years ago! But the inertia is very strong. There are just too many young researchers who aspire to have someone say โin their Nature paperโ referring to their work!
22.12.2025 21:56 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0