@meestersmd.bsky.social
Pediatrician – ID physician 🧫 | MD MPH PhD | 🇳🇱🇧🇪🇬🇧🇨🇦 trained | Passionate about AMS, clin pharm, adolescent health, TxID & MedEd | 🌈 in medicine | Views my own YVR, #beautifulbc, Canada 🍁
Decades of rigorous and scientifically sound research have proven that vaccines do not cause autism. CDC’s decision to change language on its website reversing that finding is reckless & harmful.
Our statement w/ @hivma.bsky.social, APIC, @sheaepi.bsky.social & @sidpharm.bsky.social: bit.ly/3XEc0KH
Excited to be in Toronto for day 1 of @impactrials.bsky.social summit! Looking forward to connecting with fellow clinical trial enthusiasts!
18.11.2025 14:15 — 👍 0 🔁 0 💬 0 📌 0Agree- S aureus infections 🦠 can be very complex, but a median IV duration of 24.5 days seems way too long
10.06.2025 07:53 — 👍 0 🔁 0 💬 0 📌 0@aliciad3.medsky.social @buonsenso.bsky.social @alastairmca30.bsky.social
09.06.2025 20:03 — 👍 2 🔁 0 💬 1 📌 0
👉 Please do share your thoughts—would love to hear how others are approaching this.
journals.lww.com/pidj/abstrac...
Still, this study adds to evidence supporting daptomycin doses of 10 mg/kg/day or even higher, and worth further study.
But it also underscores the ongoing need for antimicrobial stewardship in complex pediatric infections.
Several combos raise (my) eyebrows:
🧪 teicoplanin + amox-clav + vancomycin + cefazolin
🧪 amox-clav + rifampin + amikacin
❗Even in what is most likely mono-bacterial!
This reflects a broader issue: indication creep and layering of MRSA agents without clear rationale. #AMS
🔸 All patients were on other antibiotics with daptomycin.
🔸 10/12 MSSA cases got cefazolin concurrently—so why add dapto at all?
🔸 After IV, many continued dual oral staph coverage (e.g., amox-clav + TMP/SMX).
Hard to isolate what worked.
#AntimicrobialStewardship
#AMR
#microsky
💉 High-dose daptomycin (~10 mg/kg/day) was used in >50%, with clinical success in 90%, major CRP reductions, and no serious adverse events.
Median duration: 24.5 days IV
Many transitioned to oral step-down.
Sounds promising—until you look closer.
🦴 New in @pidjournal.bsky.social: Denina et al. report a 3-year prospective series of 20 children with complex bone & joint infections, all with S. aureus confirmed (local site and/or blood).
MSSA: 60%
MRSA: 35%
MRSE: 1 case
All received daptomycin.
#PedsID #PedsIDsky #PaedsID #IDsky
a thread🧵👇
#jongeklaren #artsinopleiding #dokterinopleiding #geneeskunde #artsleven
@medischcontact.bsky.social
www.medischcontact.nl/opinie/blogs...
#dutchonly #seulementenneerlandais
📣 Mijn nieuwe blog staat online!
Over kinderarts zijn in Canada — in een regio vol beren, bergen en bevroren vliegvelden.
En over eindverantwoordelijkheid, terwijl je de patiënt alleen kent via een krakende telefoonlijn…
New here — excited to connect!
Peds ID 🧫 physician in 🇨🇦 (🇳🇱🇧🇪🇬🇧🍁trained) with interests in clin pharm & ID epi.
Passionate about congenital infections, adolescent health, TxID & MedEd.
outdoorsy (⛷️ in winter, 🚴 year-round) | 🌈 in medicine
See you at #ESPID2025!
#PedsID #PedsIDSky #IDsky
