Danilo Buonsenso

So the Pediatric Infectious Diseases games are ready to go in 2d!
Impressive amount of different european countries participating this year!

I know, in these cases it’s not worth it

When Patients Ask for a Cure: A Doctor’s Honest Reflection on Long Covid and ME/CFS In the past months, my inbox (and whatsapp!) has filled with messages from patients and families living with Long Covid or ME/CFS.

When Patients Ask for a Cure: A Doctor’s Honest Reflection on Long Covid and ME/CFS

danilobuonsenso.substack.com/p/when-patie...

Oxaloacetate, long COVID and ME/CFS: what the new trial shows — and a pragmatic (non-prescriptive) scheme for clinicians Fatigue and cognitive fog remain among the most disabling complaints for people with long COVID and with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

Oxaloacetate, long COVID and ME/CFS: what the new trial shows — and a pragmatic (non-prescriptive) scheme for clinicians

danilobuonsenso.substack.com/p/oxaloaceta...

let us know

with the only and one!!

Low-Dose Rapamycin for ME/CFS and Long COVID: New Clinical Data, Promising Hints, and Ongoing Caution Over the past months, I have written several posts exploring the potential role of low-dose rapamycin in Long COVID and ME/CFS (Part 1, Part 2, Part 3).

Low-Dose Rapamycin for ME/CFS and Long COVID: New Clinical Data, Promising Hints, and Ongoing Caution

danilobuonsenso.substack.com/p/low-dose-r...

What’s new in the Long COVID / ME/CFS endothelial story — and what that means for treatment You may remember that in earlier posts we discussed how both Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) appear to share a key feature: endothelial inflammation/dysfunct...

What’s new in the Long COVID / ME/CFS endothelial story — and what that means for treatment

danilobuonsenso.substack.com/p/whats-new-...

you’ll read several success papers about #nirsevimab and #RSV but to make it a successful and long term sustainable interventions you need to read also of out chorus provocative voices, like this one !

rdcu.be/ePXTa

Long COVID and the AMPA Pathway: New Clues from Brain Imaging Over the past few years, Long COVID has become one of the most puzzling and impactful conditions in post-viral medicine — especially for the many children and adults who continue to experience “brain ...

Long COVID and the AMPA Pathway: New Clues from Brain Imaging

danilobuonsenso.substack.com/p/long-covid...

Conversations on IVIG and Monoclonals A recording from MD, PhD's live video

Conversations on IVIG and Monoclonals in #LongCovid #MECFS

danilobuonsenso.substack.com/p/conversati...

The second-order effects that the COVID-19 pandemic has had on pediatric populations SARS-CoV-2 can have long-term health consequences that persist beyond acute infection. While this is evident in adults and the elderly, the impact on children and adolescents remains under recogniz...

new on covid impact on kids

www.tandfonline.com/eprint/ZY2VI...

retweeting allows direct engagement

When There Are No Treatments: Why Off-Label Drugs Should Be on the Table for Long Covid and ME/CFS What Does “Off-Label” Really Mean?

The latest from @buonsenso.bsky.social rings so true:

Yet when patients and families ask for treatments, the answer is almost always: “There are no approved options.”

open.substack.com/pub/danilobu...

#PedSky
#LongCovidKids
#pwLC
#pwME

Paediatric invasive group A streptococcal infections and associations with viral infections in 15 European countries after lifting non-pharmaceutical interventions against SARS-CoV-2: an interrupted t... After lifting non-pharmaceutical interventions (NPIs) against the transmission of SARS-CoV-2, various countries experienced an increase in invasive Gr…

glad our team contributed to another very important study on iGAS.
PEGASUS network

www.sciencedirect.com/science/arti...

“We Can’t Do This Alone”: A Doctor’s Plea for Support in Caring for Long COVID and ME/CFS Patients As a pediatrician and infectious disease specialist, my days are full.

“We Can’t Do This Alone”: A Doctor’s Plea for Support in Caring for Long COVID and ME/CFS Patients

danilobuonsenso.substack.com/p/we-cant-do...

again viruses and dementia.
those of you negating this slow science progression and patients prevention options.

all started w #LongCovid revolution. years ago I said LC is clearly giving this indication and now science is confirming

all in my book: tinyurl.com/4tsvhwat

Working (and Keeping Your Salary) When Long COVID or ME/CFS Makes Full-Time Work Impossible 1.

Working (and Keeping Your Salary) When Long COVID or ME/CFS Makes Full-Time Work Impossible

danilobuonsenso.substack.com/p/working-an...

Point-of-care lung ultrasound to differentiate bacterial and viral lower respiratory tract infections in pediatric age: a multicenter prospective observational study Scientific Reports - Point-of-care lung ultrasound to differentiate bacterial and viral lower respiratory tract infections in pediatric age: a multicenter prospective observational study

I have a strongest feeling and growing evidence that lung ultrasound will play a growing role not only in diagnosing pneumonia but also in understanding which cases need antibiotics

rdcu.be/eJ1tQ

Can IV Saline Help Kids and Adults with ME/CFS? Living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) can be exhausting, not only because of the illness itself but also because of the limited treatment options available.

Can IV Saline Help Kids and Adults with ME/CFS?

danilobuonsenso.substack.com/p/can-iv-sal...

glad @TheLancetInfDis gave #LongCovid kids the voice they deserve, and with a powerful title as I love.
that’s a big change compared with the past

t.co/TyOo8jmQOr

The Lancet @buonsenso.bsky.social

The take-home message from this study is clear: long COVID is here to stay, even in children, and can be exacerbated by reinfections and sustained by high viral circulation. Governments, health-care systems, and

#LongCovidKids

www.thelancet.com/journals/lan...

Helping Your Child Through Long Covid or ME/CFS: What Parents Can Do, Age by Age Long Covid and ME/CFS can affect children, adolescents, and young adults in profoundly different ways.

Helping Your Child Through Long Covid or ME/CFS: What Parents Can Do, Age by Age

danilobuonsenso.substack.com/p/helping-yo...

Nasal Azelastine and COVID Prevention: What a New Study Tells Us — And Why It Might Matter for Long COVID / ME/CFS Introduction

Nasal Azelastine and COVID Prevention: What a New Study Tells Us — And Why It Might Matter for Long COVID / ME/CFS

danilobuonsenso.substack.com/p/nasal-azel...

one of the best feedback I could receive, mostly from the emotional perspective.

you can join the discussion on #ivig for #LongCovid or #mecfs on my blog

open.substack.com/pub/danilobu...

this message tells a lot about #LongCovid
1- pts recognized soon can recove, also entirely
2- reinfections can bring you doing again

this means a general predisposition against over reaction to viral infection, but also to try to avoid reinfections and maybe to treat them

so true

Could Intravenous Immunoglobulin (IVIG) Help in Long Covid and ME/CFS? A clinical overview for families and physicians — by Buonsenso and the Kids

agree, written this

open.substack.com/pub/danilobu...

When I was a teenager, an early diagnosis and good advice would have been life changing.

What Is ME/CFS — And Why Should Pediatricians Care? ME/CFS is a complex, multi-system chronic illness that can strike both adults and children.

What Is ME/CFS — And Why Should Pediatricians Care?

danilobuonsenso.substack.com/p/what-is-me...