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Secombe

@secombe-lab.bsky.social

We love all things related to KDM5, chromatin and transcription. Interested in understanding the basis of KDM5-induced neurodevelopmental disorders using Drosophila and human iPSC models. πŸ‡¦πŸ‡ΊπŸ‡ΊπŸ‡ΈπŸ³οΈβ€πŸŒˆ | secombelab.org |

225 Followers  |  356 Following  |  8 Posts  |  Joined: 13.11.2024  |  2.3048

Latest posts by secombe-lab.bsky.social on Bluesky

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Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.

PREACH!

www.nature.com/articles/s41...

10.10.2025 20:48 β€” πŸ‘ 82    πŸ” 56    πŸ’¬ 3    πŸ“Œ 7
Post image 19.08.2025 23:29 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Congrats!! Well deserved.

09.07.2025 00:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Wonderful news.

24.05.2025 10:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Graduate Student Researchers Honored at 2025 Marmur Symposium

Three Einstein graduate students were honored recently for their contributions to #scientific #research at the 29th Julius Marmur Award symposium. Einstein's Graduate Programs in the Biomedical Sciences established the prize in memory of Dr. Marmur, a pioneering molecular biologist and mentor.

21.04.2025 20:36 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Congratulations Ian, Matanel and Elizabeth!!

21.04.2025 23:29 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A graphic showing that 50.6% of research projects with "LGBT" search terms have been cancelled. 45.8% of grants with "transgender" in the search terms have been cancelled. 45.5% of research grants with "vaccine hesitancy" have been cancelled. 3.4% grants with "HIV" or "AIDS" have been cancelled.

A graphic showing that 50.6% of research projects with "LGBT" search terms have been cancelled. 45.8% of grants with "transgender" in the search terms have been cancelled. 45.5% of research grants with "vaccine hesitancy" have been cancelled. 3.4% grants with "HIV" or "AIDS" have been cancelled.

The US National Institutes of Health has terminated nearly 800 research projects at a breakneck pace, wiping out significant chunks of funding to entire scientific fields

Read the full story: https://go.nature.com/3EuFRPV

18.04.2025 10:19 β€” πŸ‘ 288    πŸ” 222    πŸ’¬ 5    πŸ“Œ 23
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NIH scientists have a cancer breakthrough. Layoffs are delaying it. A big step forward in cancer therapy has been slowed by layoffs and new restrictions at the National Institutes of Health, where it was developed.

Donald Trump and Elon Musk are disrupting a breakthrough cancer treatment so they can fund tax cuts for billionaires.

Tell your friends.

06.04.2025 23:28 β€” πŸ‘ 1856    πŸ” 1038    πŸ’¬ 20    πŸ“Œ 27
Research Fellow in Neurogenetics to investigate how experience shapes the brain - School of Biosciences - 98709 - Grade 7 A Research Fellow with experience in behavioural neurogenetics of Drosophila is sought. The aim of the project is to investigate how experience and behaviour shape the brain throughout life, the impac...

Last few days to apply!
Post-doctoral position 3 years Wellcome funded in UK
To investigate how experience shapes the brain
Drosophila neurogenetics, imaging, behaviour
Deadline 19/3/25
Pls RP.
#drosophila
#postdoc
#jobs
Apply here

edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

15.03.2025 08:58 β€” πŸ‘ 5    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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NIH In Your State - United For Medical Research Select a state on the map to see the impact of NIH funding across America.

Good resource about your state...

www.unitedformedicalresearch.org/nih-in-your-...

02.03.2025 12:55 β€” πŸ‘ 139    πŸ” 89    πŸ’¬ 6    πŸ“Œ 10
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Renowned geneticist Francis Collins retires from NIH, urging 'respect' for embattled workers Dr. Francis Collins, a renowned geneticist, and former longtime director of the National Institutes of Health, is retiring from the government agency and urging β€œrespect” for its embattled workers.

"When you hear about patients surviving stage 4 cancer because of immunotherapy, that was based on NIH research over many decades. When you hear about sickle cell disease being cured because of CRISPR gene editing, that was built on years of research supported by NIH"

apnews.com/article/nih-...

01.03.2025 21:44 β€” πŸ‘ 335    πŸ” 126    πŸ’¬ 2    πŸ“Œ 9
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NIH is again throttling research funding in defiance of a federal court order A freeze on "new and continuation awards" will "remain in place" pending DEI review, states a new internal memo.

Despite court order, NIH grants remain frozen. Newly awarded grants, grants with fundable scores, & funds for a new budget cycle of a current project are all *FROZEN*πŸ₯Ά and not being released. US research is being choked to death & is on life support right now www.motherjones.com/politics/202...

26.02.2025 12:04 β€” πŸ‘ 3869    πŸ” 1580    πŸ’¬ 175    πŸ“Œ 83
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Faculty-Tenure Track, Department of Developmental and Molecular Biology - Bronx, New York job with Albert Einstein College of Medicine | 12835514 Faculty-Tenure Track, Department of Developmental and Molecular Biology US-NY-Bronx Job ID:Β 2025-17126 Type:Β Research # of Openings:Β 1 Category:Β F...

Join the Department of Developmental & Molecular Biology @einsteinmededu.bsky.social ! 🧬✨
Are you passionate about cutting-edge research and collaborative science? We are looking for youπŸ˜‰
Come be part of a department where curiosity meets impact! πŸš€
Learn more and join usπŸ‘‡
#ResearchExcellence #JoinUs

26.02.2025 03:31 β€” πŸ‘ 8    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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NIH funding freeze stalls applications on $1.5 billion in medical research funds The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
23.02.2025 02:07 β€” πŸ‘ 321    πŸ” 132    πŸ’¬ 7    πŸ“Œ 10
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NIH funding freeze stalls applications on $1.5 billion in medical research funds The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

22.02.2025 18:39 β€” πŸ‘ 3586    πŸ” 1487    πŸ’¬ 161    πŸ“Œ 132
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Here are some data documenting the funding "pause" pulled from NIH Reporter. Current results (FY25) (Red) are compared with results from FY21 (first year of Biden Administration) and FY24.

Note that data from Reporter lag behind release of NoAs by ~1 week.

I will be tracking this going forward.

21.02.2025 04:49 β€” πŸ‘ 186    πŸ” 89    πŸ’¬ 6    πŸ“Œ 3
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A FAQ on federal research cuts ...

I wrote up an FAQ about the recent federal grant cuts. A few points: 🧡

20.02.2025 03:34 β€” πŸ‘ 59    πŸ” 30    πŸ’¬ 2    πŸ“Œ 7
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Science under siege: Trump cuts threaten to undermine decades of research Sweeping layoffs, funding freezes and executive orders have provoked outcry among federal researchers and their university partners, who fear that science itself is under siege.

The Trump administration’s actions will be tested in the courts and fought by unions. But scientists and university leaders said they have another fight ahead: They need to convince Americans β€” and Congress β€” that science is worth the investment.

19.02.2025 20:50 β€” πŸ‘ 209    πŸ” 68    πŸ’¬ 35    πŸ“Œ 7
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Looking for an enthusiastic post-doc to investigate how experience shapes the brain. Drosophila neurogenetics, molecular and cellular mechanisms, imaging, optogenetics, neural circuits and behaviour will be used. At University of Birmingham campus, UK. Application deadline 19 March.
Pls RT.

10.02.2025 08:57 β€” πŸ‘ 13    πŸ” 15    πŸ’¬ 0    πŸ“Œ 2
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University leaders right nowβ€¦πŸš½πŸ€’

07.02.2025 23:28 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 2    πŸ“Œ 2
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Congress must support robust federal funding for the NIH NIH-funded research supports scientific discovery that benefits millions of Americans.

AAMC - Congress must support robust federal funding for NIH

07.02.2025 01:17 β€” πŸ‘ 11    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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Trump's NIH Freeze Puts Scientific Research at Risk America’s best scientific minds are scrambling to determine the impact of the disruption.

Excellent perspective by @lisamjarvis.bsky.social @bloomberg.com on the deep freeze at NIH

24.01.2025 21:28 β€” πŸ‘ 220    πŸ” 94    πŸ’¬ 5    πŸ“Œ 6

I hear there are stories coming, but putting the brakes on our country’s world-leading medical research system feels like a five alarm fire and I don’t see a newspaper that even has it on the front page yet

23.01.2025 03:29 β€” πŸ‘ 7611    πŸ” 2168    πŸ’¬ 177    πŸ“Œ 66

The antidote for despair is action ❀️

* Dial (202) 224-3121
* Enter zip code
* Leave voicemail
* Say β€œMy name is ___, I’m a constituent in [town]. (If clinician/scientist, say so)

β€œThe NIH freeze harms research and patients and must be lifted immediately.”

Be brief. Staffers tally all calls. Go! βœ…

23.01.2025 03:21 β€” πŸ‘ 1292    πŸ” 917    πŸ’¬ 63    πŸ“Œ 55

Gorgeous.

20.01.2025 19:29 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Wonderful visit.

17.01.2025 22:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I have officially reached that dreaded phase of grant writing where my files are called _final. And then _finalV2, _final_final etc. πŸ˜‚

13.01.2025 12:47 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

:(

30.12.2024 10:21 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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ECHO Anniversary: In the Room Where it Happened | Einstein Magazine As the Albert Einstein College of Medicine’s ECHO marks 25 years, Einstein alumni recall the earliest day of the free clinic, which became a national model.

We're thankful for the Einstein alumni who made history in 1999 when they opened the doors to the first student-run health clinic in New York City, called the ECHO Free Clinic. For its 25th anniversary, several alumni who helped shape that clinic in its earliest days reflect on its legacy. #MedSky

27.11.2024 17:04 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Report: Every dollar of NIH research funding doubles in economic returns Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an

Research funded by NIH generated $2.46 in economic activity for every $1 of funding in 2023 [a total of $92.9 billion]

www.fiercebiotech.com/research/rep...

17.11.2024 23:55 β€” πŸ‘ 248    πŸ” 106    πŸ’¬ 2    πŸ“Œ 13

@secombe-lab is following 19 prominent accounts