Vanderbilt Center for Structural Biology

Vanderbilt’s Ancora Partnership: A collaborative journey toward health care innovation Since the inception of the Ancora Innovations partnership in 2018, Vanderbilt and Deerfield Management have enjoyed a robust collaboration. Deerfield’s commitment includes significant support for adva...

@vanderbilt.edu and Ancora Innovations continue their collaboration to advance translational research and health care innovation.

VICB recognizes the importance of partnerships that connect discovery with real-world impact.

Learn more: bit.ly/47T1ZOP

🧬 🪦 Dean emeritus Larry Marnett, Mike Goodman (staff scientist in the Sanders lab), and senior advisor to the dean Chuck Sanders paid their annual visit to the grave of Oswald Avery, the scientist “best known for his discovery that DNA serves as genetic material.
profiles.nlm.nih.gov/spotlight/cc

A recent study from ZJ Yang Lab examines how structural flexibility contributes to cold adaptation in cellulases.

Read more:
www.vanderbilt.edu/csb/2025/10/...

Vanderbilt leaders in filling the biomedical research pipeline shine at national meeting VUSM played a major role in a national conference that showcased the critical need to train biomedical researchers to advance medical care.

Some of our leaders attended the 2025 Biomedical Research Training Conference, hosted by the Association of American Medical Colleges’ Group on Research, Education and Training. They shared Vanderbilt's innovative approaches to trainee recruiting, mentoring, and more! 👉 news.vumc.org/2025/10/08/v...

From lab to legacy: Marnett’s trainees gather to toast a life in science and service In a heartwarming tribute to a remarkable career, more than 70 of his former graduate students and postdoctoral scholars recently traveled from across the globe for a three-day festivity on Oct. 3–5 t...

Colleagues and former trainees gathered to honor Dr. Larry J. Marnett, Dean Emeritus, Distinguished Professor, and founding leader of the Vanderbilt Institute of Chemical Biology (VICB).

Celebrating 50 years.

🔗 Read more: bit.ly/4nhbP2w

@vanderbilt.edu @vubasicsciences.bsky.social #wednesday

Vanderbilt scientist tackles key roadblock for AI in drug discovery Vanderbilt’s Dr. Benjamin P. Brown is improving the way the field of drug discovery creates machine learning algorithms to predict a protein’s interactions with a small molecule. These improvements br...

Congrats to @bpbrown.bsky.social on his single-author paper recently published in @pnas.org! Read more on how he tackles a key roadblock for AI in drug discovery
medschool.vanderbilt.edu/basic-scienc...
@vubasicsciences.bsky.social

Investigating antibiotic characteristics from the computer SBGrid member Jens Meiler uses Rosetta to design antibiotic peptides called lanthipeptides with antibiotic properties.

@caltech.edu doctoral student Vida Robertson highlighted a publication from Jens Meiler, from @vanderbilt.edu, who describes using Rosetta to design antibiotic peptides called lanthipeptides with antibiotic properties.

Read more here: buff.ly/d6k8HvB

#SBGrid #NMR #ProteinDesign

Open science! 📖 Notes from the first @andolab.bsky.social beamtime for the @diffuseproject.bsky.social - check it out!

diffuse.science/logbook/beam...

¡No olviden solicitar a nuestro premio de viaje para asistir a la conferencia @biophysicalsoc.bsky.social #BPS2026! Vean más detalles de cómo solicitar en el fondo 👇

---

Don't forget to apply to our travel award to attend the #BPS2026 Meeting! See application instructions below 👇

With a new collaboration called diffUSE, the @stephanieaw.bsky.social lab is helping to advance our understanding of protein motion, leading to a new paradigm in dynamic structural biology.
@vubasicsciences.bsky.social
medschool.vanderbilt.edu/basic-scienc...

Congratulations to @dougkojetin.bsky.social!

We thank our sponsor #Pfizer for this amazing opportunity! 🤩🤩🤩

SBGrid Consortium - Software Updates The SBGrid Consortium is an innovative global research computing group operated out of Harvard Medical School. SBGrid provides the global structural biology community with support for research…

August's software push includes updates to over 20 titles including ACPyPE, AlphaPulldown, Boltz, CCP-EM, ChimeraX, CryoDRGN, Doppio, fpocket, Geneious, Gnuplot, ISOLDE, IsoNet, MDAnalysis, MemBrain-seg, Napari, NMRFx-Analyst, and many more.

More information here: buff.ly/KhZw2Tb
#SBGrid #Software

Diffuse Project Interest Form Interested in the Diffuse Project? Please provide your information to help us shape community engagement and potentially direct you to the right project member.

Want to get involved, share your ideas, or just stay in the loop with email updates? Let us know here: forms.gle/37pK2smABwbg...

Linker‐mediated domain separation enhances cold adaptation in cellulases Cold-adapted cellulases have the potential to reduce energy demands in industrial processes by enabling efficient cellulose saccharification at lower temperatures. However, the structural basis of co...

Recent computational work on cold-active bidomain cellulase from the @mutexazjy.bsky.social lab published in Protein Science: "Linker‐mediated domain separation enhances cold adaptation in cellulases"
@vuartsci.bsky.social @vanderbiltvicb.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...

Cool news from the @stephanieaw.bsky.social lab!

🎊Congratulations to CSB researcher Yi Ren on her promotion to Associate Professor of Biochemistry! 🥂

Using the Eskind Biomedical Library to access thousands of academic journals As a researcher affiliated with Vanderbilt University, you should never pay for a scholarly journal article. Vanderbilt’s system of libraries offers several tools that can be helpful when accessing…

📚 Did you know? Vanderbilt-affiliated researchers have access to thousands of academic journal articles through the Annette and Irwin Eskind Biomedical Library! Several tools are offered that can be helpful when accessing library resources on the open web. 👉 medschool.vanderbilt.edu/basic-scienc...

It's just around the corner! Register now: medschool.vanderbilt.edu/vicb/2025-st...

Deadline extended! Submit your images to the Second Annual CISR Life is Beautiful Image Contest! New deadline is July 18. Open to anyone with CISR-acquired images. More details here. medschool.vanderbilt.edu/basic-scienc...

School of Medicine Basic Sciences Staff Spotlight: Sheila Elder Meet Sheila Elder, an administrative officer in the Vanderbilt University School of Medicine Basic Sciences who provides financial and administrative leadership for the Warren Center for Neuroscien…

🌟 Meet Sheila Elder, an administrative officer for the WCNDD whose passion and dedication make research and operations run smoothly behind the scenes. A fun fact about her? "It has been scientifically proven that I make the best banana pudding in the world." medschool.vanderbilt.edu/basic-scienc...

LassoPred: a tool to predict the 3D structure of lasso peptides - Nature Communications Ouyang et al. present LassoPred, a computational tool to accurately predicts the 3D structure of lasso peptides and offers an accessible online prediction tool to the scientific community.

New work from Yang Lab, Link Lab and Yi-Lei Zhao takes a first step toward structural prediction of RiPPs: lasso peptide.
nature.com/articles/s41...
Access the tool here: lassopred.accre.vanderbilt.edu

@vanderbiltvicb.bsky.social

New findings from the @chazinwalter.bsky.social lab & collaborators suggest that combining 5hmC with olaparib can restore the sensitivity of chemoresistant BRCA1/2-deficient cells. 🎉Congrats to 1st author Suhas Kharat!
@vubasicsciences.bsky.social

doi.org/10.1016/j.jb...

Excellence in corporate collaboration event recognizes staff achievements in advancing corporate partnerships The second annual Excellence in Corporate Collaboration Luncheon on May 22 brought together members of the Vanderbilt community at Alumni Hall to celebrate a shared commitment to partnership and…

🌟 A big congratulations to the BRET ASPIRE team including Ashley Brady, Mary Gray Lindstrom, Angela Zito and Kathy Gould for being a recipient of the Excellence in Corporate Collaboration Awards! This recognition is for their leadership of ASPIRE on the Road. news.vanderbilt.edu/2025/06/11/e...

MALDI magic: AIMS empowers scientists through transformative learning Just as swallows journey to San Juan Capistrano, California, and monarch butterflies migrate to Michoacan, Mexico, each spring, so mass spectrometrists from across the globe converge on Vanderbilt …

🔬The AIMS program at Vanderbilt trains scientists how to use MALDI imaging mass spectrometry—a technique that allows for spatial mapping of molecules in tissues. The most recent event, hosted early May, included researchers from all over the world. 🌎 medschool.vanderbilt.edu/basic-scienc...

The external speakers are set and ready to navigate the intersection of #AI & #StructBio for the Bridging Atoms and Algorithms: A Symposium on AI and Structural Biology.
🗓️Tuesday & Wednesday, March 17–18, 2026
🏫Campus of Vanderbilt University
bit.ly/4ldBOaz

Stand up for Science. ALWAYS. #sciencematters #standupforscience
mailchi.mp/proteinsocie...

Spring Faculty Meeting provides important updates on School of Medicine’s progress During Vanderbilt University School of Medicine’s Spring Faculty Meeting and Awards Program, Jeff Balser, MD, PhD, shared important updates.

Congrats to Lisa Monteggia, Ege Kavalali, Kevin Schey, Ken Lau, and Chuck Sanders who were recognized for their impactful research, mentorship, and service at the Vanderbilt University School of Medicine Spring Faculty Meeting! 👏 Learn more about their recent awards 👉 news.vumc.org/2025/06/06/s...

New research from the Plate and Meiler labs offers promise for treatment-resistant cystic fibrosis patients.
1st author Eli McDonald has personal reasons for the research. Read more ...
medschool.vanderbilt.edu/basic-scienc...

@vubasicsciences.bsky.social @vanderbiltvicb.bsky.social

Meet @prash-singh.bsky.social of the Iverson lab. He’s getting used to the spotlight from his recent @smartereveryday.bsky.social appearance. He’s still the down-to-earth Prash who is always ready to respond to the “call of duty."
bit.ly/prash2025
@vubasicsciences.bsky.social #cryoem #research