Charly Lamothe

@jphysiol.bsky.social

Co-first authorship with Sophie Bagur and Etienne Gosselin.

We found although these responses are found throughout the central auditory system, they provide richer information about elapsed sounds in the auditory cortex.

Sound offset responses become highly informative in the auditory cortex Abstract figure legend Using large datasets of neural responses to diverse sounds recorded across four stages of the mouse auditory system (depicted and colour-coded on the left), offset responses oc...

Delighted to announce that my first postdoc work with @bathellierlab.bsky.social got on offset responses in the auditory system got published in the Journal of Physiology!

tinyurl.com/3amwj39w

New study of the lab showing that sleep preserve sound representations geometry in the auditory cortex but intermittently blocks the transfer of sensory information, possibly to provide both opportunities for surveillance and offline processing.
www.biorxiv.org/content/10.1...

Two postdoc positions in the lab within the ERC Synergy project "Chronology" in collaboration with S. Ostojic, M. Jazayeri and V. van Wassenhove @virginievanw.bsky.social . Two focuses: sound sequences representations across the brain & novel all-optical technology. Contact: brice.bathellier@cnrs.fr

Merci Étienne !

Co-first authorship with Sophie Bagur and Etienne Gosselin.

Sound offset responses become highly informative in the auditory cortex The entire auditory system downstream of the cochlea features pronounced offset responses, which follow the termination of sounds. Because of their ubiquity, it is still an unsolved question whether o...

Happy to announce my first postdoc preprint at @bathellierlab.bsky.social on offset responses in the auditory system! We found although these responses are found throughout the central auditory system, they provide richer information about elapsed sounds in the auditory cortex.

tinyurl.com/3y2nvpr9

With Manon Obliger-Debouche, Paul Best, Régis Trapeau, Sabrina Ravel, Thierry Artières, @ricard.bsky.social & Pascal Belin on Scientific Data @natureportfolio.nature.com

#primate #marmoset #vocalizations

A large annotated dataset of vocalizations by common marmosets - Scientific Data Scientific Data - A large annotated dataset of vocalizations by common marmosets

I'm pleased to announce the publication of my PhD works, a large annotated dataset of vocalizations by common marmosets. With over 800,000 recordings and 253 hours of data, this is the largest annotated dataset. Check it out and let me know what you think!
www.nature.com/articles/s41...

A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.

Neuropixels and Optogenetics are delighted to announce the birth of

Neuropixels Opto

Combining high-resolution electrophysiology and optogenetics

Today in bioRxiv

960 sites, 28 emitters, 2 colors

By Lakunina, @karolinazsocha.bsky.social, Ladd, et al

www.biorxiv.org/content/10.1...

(1/2)

It's finally out!

Visual experience orthogonalizes visual cortical responses

Training in a visual task changes V1 tuning curves in odd ways. This effect is explained by a simple convex transformation. It orthogonalizes the population, making it easier to decode.

10.1016/j.celrep.2025.115235

Elife has a new editor-in-chief. An opportunity to remember that Elife proposes a modern peer review system fostering transparency, fairness, and immediacy. Elife has contributed to move the entire system in these important directions, and hopefully will continue doing so.

⏳ A reminder that there is just under one week left to register for the Braincoder conference!

Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortex Responses to local and global violations in sound sequences are prediction errors and not simply the consequence of stimulus-specific adaptation.

Catching up from the dead time w/o X, here is the excellent recently published study by Sara Jamali with @standehaene.bsky.social using the local-global prediction paradigm in mice. Oddball signaling is not just adaptation. Sequence chunking responses in VIPs. And some more doi.org/10.7554/eLif...

Episodic and associative memory from spatial scaffolds in the hippocampus - Nature A neocortical–entorhinal–hippocampal network model based on grid cell states recapitulates experimental results and reconciles the spatial, associative and episodic memory roles of the hippocampus.

New modelling of how episodic memory can arise from spatial mapping, just out in Nature:

www.nature.com/articles/s41...

Dynamical constraints on neural population activity - Nature Neuroscience Oby, Degenhart, Grigsby and colleagues used a brain–computer interface to challenge monkeys to override their natural time courses of neural activity. They found the time courses to be highly robust, ...

Using a brain–computer interface to challenge monkeys to override their natural time courses of neural activity reveals that the time courses are highly robust, suggestive of network-level computational mechanisms

@aaronbatista.bsky.social and colleagues

www.nature.com/articles/s41...

📢 The Braincoder conference will take place in Gardanne in the South of France, on the 20th and 21st February 2025! Braincoder will explore the topic of brain-machine interfacing and features an exciting line-up of speakers.

A spatial code for temporal information is necessary for efficient sensory learning The auditory system transforms temporal information in sounds into spatial information for rapid associations with decisions.

A milestone paper for the lab. First causal demonstration of the impact of temporal information format on learning & a clear demonstration that the mouse auditory system structures sound representations very similar to what sound categorization deep networks do. www.science.org/doi/10.1126/...