@jphysiol.bsky.social
The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
Paolo Spaiardi et al. found that transient capacitance changes recorded from vestibular type I hair cells are produced by GK,L gating and do not involve #neurotransmitter exocytosis π§ π
π Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Bettina K. M. Firmke of uniregensburg.bsky.social et al. found that #hypoxia-inducible factor-2 stabilization is not sufficient to induce erythropoietin production in deeper medullary #fibroblasts π¬ π
π Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
π£ CALL FOR PAPERSπ£
Examining New Approach Methodologies #NAMs in #precisionmedicine ππ
Submit by 28 February 2026 β°
π For topics and more information:
www.sciencedirect.com/special-issu...
In a recent study, Alexey V. Dvornikov & Samantha P. Harris of uarizona.bsky.social observed that #myosin-binding protein C slows #cardiac myofibril relaxation kinetics π« π
π Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
π£ Call for Papersπ£
For the special issue "Placental and fetal brain interfaces: how effective are they in protecting against drugs and toxins?" π§ π
β° Deadline: 15 October 2025
π For more information & how to submit: physoc.onlinelibrary.wiley.com/hub/journal/...
Leah S. Halls of ugaresearch.bsky.social et al. observed that #dihydrosterculic acid induces #hepatic PPARΞ± target gene expression in mice 𧬠π
π Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
This #Perspective by Sandra K. Hunter examines #testosterone and androgen receptors in females, based on research by Alexander et al. (2025) βοΈ
π Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Recent #Research by Guillaume P. Ducrocq et al. finds that GsMTx-4 inhibits the #exercise pressor reflex and the muscle #mechanoreflex primarily through TRPC inhibition π π¬
π π Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Dayna A. Zimmerman et al. observed that #metformin and #insulin exacerbate one-carbon metabolism deficits in #pregnant growth restricted rats and impacts the placenta, fetal liver and pancreas π π
π Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Andrew W. D'Souza & Michael K. Stickland discuss the work of Sayegh et al. (2025) examining peripheral chemoreflex constraint of skeletal muscle blood flow βοΈ
Read the #Perspective here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
This #Review article by Khaoula El Mekkaoui (of ucdavis.bsky.social, vtt.fi & csaalto.bsky.social) et al. examines the impact of the social exposome in #cardiovascular health and disease π«π
π Read the #OpenAccess article here: www.jprecisionmedicine.org/article/S305...
Hsuan-Yu Wan et al. investigated regional cerebral perfusion and sympathetic activation during exercise in #hypoxia and #hypercapnia, offering preliminary insight into βCushing's mechanismβ βοΈ π§
π Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Sergi Garcia-Retortillo & Plamen Ch Ivanov investigated the dynamics of #cardio-muscular networks in exercise and #fatigue π«π
π Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Our latest issue is now live!π
Featuring cover art from Thomasi et al. that shows calcium activity over time among cholinergic entericΒ #neurons in neurocircuits that control #gut motor function.
π π Access the issue here: physoc.onlinelibrary.wiley.com/toc/14697793...
Ann-Katrin Grotle & Audrey J. Stone present this #Perspective on the work of Ducrocq et al. (2025) examining the mystery of the mechanically sensitive component of the exercise pressor reflex βοΈ
π Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Ana Luiza C. Sayegh et al. found that peripheral #chemoreflex restrains skeletal muscle blood flow during exercise in participants with treated #hypertension π π«
π Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
This study by Richard M. Bruce of kingscollegelondon.bsky.social et al. finds that incongruent #virtualreality cycling exercise demonstrates a role of perceived effort in #cardiovascular control π« π
π Read the #Research here: physoc.onlinelibrary.wiley.com/doi/full/10....
Nathan E. Bartman of brocku.ca et al. present this #JournalClub article on sensory deception during cycling based on the investigation by Bruce et al. (2025) βοΈ π΄
π Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
This study by Alec L. E. Butenas of kstate.bsky.social et al. observes that #protein kinase C epsilon contributes to chronic #mechanoreflex sensitization in rats with heart failure π« π§
π Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Yu Huo of utexasglobal.bsky.social et al. observed that interleukin-1 type 1 receptor blockade attenuates the exaggerated #exercise pressor reflex in male UC Davis type 2 #diabetic mellitus rats π§ π«
π Read the #Research: physoc.onlinelibrary.wiley.com/doi/full/10....
βNow extended to 1st December 2025β°
29.09.2025 16:25 β π 0 π 0 π¬ 0 π 0
This #Perspective by Alec L. E. Butenas examines muscle acidosis in the exercise pressor reflex based on the study by Ducrocq et al. (2025) βοΈ
π Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
π£ Call for Papersπ£
β° Deadline: 1st October 2025 β°
For the special issue "Experimental and quantitative modelling approaches in cardiac and vascular physiology: focus on ion channels and Ca2+ regulation"
π For more information & how to submit: physoc.onlinelibrary.wiley.com/hub/journal/...
Guillaume P. Ducrocq et al. observed that lactate and hydrogen ions play a predominant role in evoking the exercise pressor reflex during #ischaemic contractions but not during freely perfused contractions π¬ π
π Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Jamie P. Kaluhiokalani et al. finds that 6 weeks of localized passive #heat therapy elicits some exercise-like improvements in resistance #artery function π¬ β¨οΈ
π Read the study here: physoc.onlinelibrary.wiley.com/doi/full/10....
Sean P. Langan presents this #JournalClub on the work of Garcia-Retortillo and Ch Ivanov (2025) examining complex (a)synchrony of heartβmuscle interactions during exercise βοΈ
π Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Juan A. Estrada et al. observed that intracerebroventricular #insulin injection acutely normalizes the augmented exercise pressor reflex in male rats with type 2 #diabetes mellitus π π§
π Read the #Research: physoc.onlinelibrary.wiley.com/doi/full/10....
In this opening #Editorial, Senior Editor Vaughan G. Macefield introduces the special issue 'Regulation of cardiovascular and skeletal muscle function during exercise' π π
Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this study, Sarah E. Alexander of deakinuniversity.bsky.social et al. find that bioavailable #testosterone and androgen receptor activation, but not total testosterone, are associated with #muscle mass and strength in females πββοΈ πͺ
πhttps://physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP286803
#Research by Kavya Phadke et al. examines atrial #cardiomyopathy resulting from loss of plakophilin-2 expressionπ« π
π Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
