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Thom Sharp

@thomsharp.bsky.social

Synthetic immunologist

551 Followers  |  125 Following  |  8 Posts  |  Joined: 12.11.2024  |  1.9718

Latest posts by thomsharp.bsky.social on Bluesky

Just 1 week left to apply for this postdoc position in my lab combining state-of-the-art structural biology techniques with immunology for therapeutic gain!

See details below - closing date is 29th July 2025.

22.07.2025 08:28 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Details | Working at Bristol | University of Bristol

We’re hiring a postdoc! πŸ”¬

Join us in Bristol, UK to study in situ structural immunology using cryoFIB-SEM + cryoET on our new Hydra Bio system. ERC-funded, 3 years, studying phagocytosis to develop new immunotherapeutics.

Closing 29 July 2025.

Info + apply: www.bristol.ac.uk/jobs/find/de...

09.07.2025 14:56 β€” πŸ‘ 8    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
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Two Bristol scientists elected as Fellows of the Royal Society Two renowned University of Bristol researchers have been elected to the Fellowship of the Royal Society, the UK’s national academy of sciences.

More on yesterday's announcement that our Director Dek Woolfson has been elected as a Fellow of the Royal Society.

www.bristol.ac.uk/news/2025/ma...

21.05.2025 10:04 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Pls re-skeet! There's a postdoc job available to join us in Bristol! We're looking for a molecular cell biologist to help us investigate plasma membrane proteostasis in neurons. Apply here by 23 April: www.jobs.ac.uk/job/DMO097/r.... If interested, do contact me and check out grieve-lab.com! Thanks!

09.04.2025 15:42 β€” πŸ‘ 9    πŸ” 15    πŸ’¬ 1    πŸ“Œ 3
Protein structure of C1 bound to IgM antibodies

Protein structure of C1 bound to IgM antibodies

Our new lab website is online!

sharplab.uk

Check it out and learn more about our research in Bristol!

09.04.2025 08:36 β€” πŸ‘ 17    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Research Associate / Senior Research Associate in de novo peptide and protein design at University of Bristol Apply for the Research Associate / Senior Research Associate in de novo peptide and protein design role on jobs.ac.uk, the top job board for academic positions in higher education. View details and ap...

πŸ“’ JOB VACANCY:

πŸ”¬ Research Associate / Senior Research Associate in de novo peptide and protein design

πŸ“ Based in the Dek Woolfson and Mark Dodding labs at University of Bristol

πŸ—“οΈ Closing date: 1 May 2025

www.jobs.ac.uk/job/DMN615/r...

03.04.2025 10:38 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Thanks Ben! Be good to chat sometime πŸ‘

19.01.2025 21:11 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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πŸ“’ JOB VACANCY

4-Year Postdoc Position in Protein Design at @bristoluni.bsky.social

Develop new peptides and proteins to manipulate, target and probe the mechanisms that underpin intracellular transport by microtubule motors.

More: www.bristol.ac.uk/jobs/find-in...

Deadline: 6 Feb 2025

10.01.2025 12:25 β€” πŸ‘ 7    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
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Postdoctoral Researcher in Structural Virology This project is focused on deciphering the role of virally encoded AAA+ ATPases in the replication cycles of Enteroviruses and Noroviruses.

I’m looking for a postdoc to join my team under a recently funded ERC Starting Grant.

If you’re passionate about structural #virology and have experience in #cryoEM SPA and/or #cryoET, get in touch!

Application deadline: January 19th.

Please share with your networks πŸ™

Job link: tiny.cc/7v33001

27.12.2024 07:59 β€” πŸ‘ 69    πŸ” 68    πŸ’¬ 1    πŸ“Œ 1

You know what they say about never releasing on a Friday… what does it say about me that I’m releasing on the last Friday before Christmas? 😬

Anyway, ISOLDE builds for ChimeraX 1.9 are now up. Enjoy!

20.12.2024 16:18 β€” πŸ‘ 48    πŸ” 13    πŸ’¬ 1    πŸ“Œ 0

We’ll soon be #hiring #postdoc researchers and #PhD students in #super-resolution #microscopy, #cryoEM, #AntibodyEngineering, and #proteindesign.

Please get in contact if you're interested!

@bristolbiodesign.bsky.social #ERCconsolidator #immunology #cryoET #biochemistry

03.12.2024 20:44 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Consolidator Grants: ERC awards €678m in grants to back excellent research across Europe The European Research Council (ERC) has awarded its 2024 Consolidator Grants to 328 researchers across Europe. These grants, totalling €678 million, aim to support outstanding scientists and scholars ...

I'm privileged to have been awarded an ERC Consolidator Grant!
erc.europa.eu/news-events/...
This award will allow my research group to solve the structures of #immune system components β€œcaught in the act”, and allow us to design and engineer the next-generation of #antibody #therapeutics.

03.12.2024 20:44 β€” πŸ‘ 13    πŸ” 1    πŸ’¬ 5    πŸ“Œ 0

We have quite a range of PhD projects this year, covering cryo-EM methods, bacteriology/bioenergetics, and infection/antibiotics/vaccines. Would really appreciate if people can RT and share with their teams!

29.11.2024 11:55 β€” πŸ‘ 27    πŸ” 25    πŸ’¬ 2    πŸ“Œ 2
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Mechanism of phage infection in the C. difficile pathogen- towards effective phage therapy at University of Sheffield on FindAPhD.com PhD Project - Mechanism of phage infection in the C. difficile pathogen- towards effective phage therapy at University of Sheffield, listed on FindAPhD.com

Fully funded Ph.D. position available in structural biology of bacteriophages.

Mechanism of phage infection in the C. difficile pathogen- towards effective phage therapy

For more details, visit:-

www.findaphd.com/phds/project...

21.11.2024 21:37 β€” πŸ‘ 6    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

I am about to be recruiting two post-docs to work on cryoEM and cryoET of amyloid aggregates... Anyone interested please drop me a line while the wheels of our HR department turn.............

18.11.2024 15:09 β€” πŸ‘ 63    πŸ” 52    πŸ’¬ 0    πŸ“Œ 4
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Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

15.11.2024 17:55 β€” πŸ‘ 72    πŸ” 81    πŸ’¬ 1    πŸ“Œ 4
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We offer two fully-funded PhD studentships to investigate ribosome hibernation in stem cells via cryoET. If you are interested, please apply here: www.exeter.ac.uk/research/ins...
or here: www.exeter.ac.uk/study/fundin.... If you have any questions, do not hesitate to get in touch!

15.11.2024 15:51 β€” πŸ‘ 17    πŸ” 14    πŸ’¬ 1    πŸ“Œ 2

Can you add me to this list too, please? Fantastic resource!

15.11.2024 07:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Funded PhD open to UK-domiciled, home fee applicants of Black African, Black Caribbean or other Black or mixed Black heritage - Alternative mitochondrial destinations of PINK1 and its role in Parkinso... PhD Project - Funded PhD open to UK-domiciled, home fee applicants of Black African, Black Caribbean or other Black or mixed Black heritage - Alternative mitochondrial destinations of PINK1 and its ro...

Want to study towards a PhD uncovering new mechanisms underlying Parkinson’s disease?

As part of our commitment to inclusivity @BristolUni are offering fully funded PhDs (+ stipend) for Black British applicants.

dm me if you’re interested in joining us.

www.findaphd.com/phds/project...

14.11.2024 20:51 β€” πŸ‘ 3    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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β€˜Game-changer' equipment will enable GW4 researchers to accelerate integrated understanding of health - GW4 Β£2.6million secured by GW4 Alliance researchers will open-up groundbreaking health research possibilities through new equipment.

Absolutely thrilled to be awarded a BBSRC ALERT2024 grant to buy a cryoFIB-SEM for in situ #cryoEM! This was a brilliant team effort, with >35 researchers contributing projects/ideas. In situ structural biology has an exciting future here in #Bristol and the south-west UK! gw4.ac.uk/news/game-ch...

13.11.2024 18:42 β€” πŸ‘ 15    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

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