Edinburgh Genomics

A few places are still available for this training course 🐍🖥️🧬

Don’t miss out, secure your place today and get ready to boost your research! 🚀

🗒️ Registration will be open until Thursday, 28th August 👇

📣 Big shout-out to Edinburgh Genomics team & Alex Twyford for leading this work on teaching plant genomics! 🌱🧬🖥️🎓
Many thanks to all participants & to ONT for supplying reagents!
#Bioinformatics #Genomics #Training @edgenome.bsky.social @nanoporetech.com
🔗 nph.onlinelibrary.wiley.com/doi/10.1002/...

📣 Fantastic opportunity to join Joris Veltman’s outstanding group at the Institute of Genetics and Cancer, the University of Edinburgh, advancing research in reproductive genomics and genomic medicine 🚀🖥️🧬

📅 Deadline: 1 Sept

@jorisveltman.bsky.social @uoe-igc.bsky.social @edinburgh-uni.bsky.social

📢 Ready to level up your coding? Join our next training course:

🐍 Advanced Python for Biologists
📅 1–5 Sept 2025 | 💻 Live online
🔗 Register: genomics.ed.ac.uk/event/advanc...

🧬 A hands-on course for life scientists ready to boost their coding skills in data analysis & tool development.

#Python 🖥️🧬

Embracing AI with integrity - UK Research Integrity Office Embracing AI with integrity A practical guide for researchers The UK Research Integrity Office (UKRIO) has launched new guidance to help researchers navigate the research integrity challenges posed by...

New guidance published @ukrio.bsky.social to support responsible AI use in research
This guidance, part of UKRIO’s priority workstream on AI and research integrity, provides a principle-based, researcher-focused resource adaptable across disciplines and technologies.
ukrio.org/ukrio-resour...

#HiFisequencing with #PacBio is rewriting the rules for dried blood spot analysis.

With Ampli-Fi and SPRQ chemistry, even ultra-low input samples can deliver full, phased genomes that change the game for newborn screening.

Read more: bit.ly/4kbrzm6

🧬 🖥️ That’s a wrap on our RNAseq Data Analysis course!

🙏 A big thank you to everyone who joined us online last week to explore the world of transcriptomics — from QC and read alignment to gene expression and interpretation.

@edinuni-irr.bsky.social @roslininstitute.bsky.social @uoe-igc.bsky.social

Join our Single-cell RNA-seq Data Analysis course, running 23–25 June 2025 online!
✅ Process single-cell RNA-seq data
✅ Perform clustering and dimensionality reduction
✅ Identify cell types and gene expression patterns
📅 Book now: genomics.ed.ac.uk/event/single...

A new compression strategy to reduce the size of nanopore sequencing data. #DataCompression #Nanopore #SequenceData #Bioinformatics #Genomics @nanoporetech.com @genomeresearch.bsky.social‬ 🧬 🖥️
genome.cshlp.org/content/earl...

Roche has given more details of their SBX NGS technology: it'll be called Axelios, and we know it's aimed at competing against Illumina SBS technology, the technology the San Diego company acquired from Cambridge UK Solexa.
I'll give you a second to catch up with it... Axelios vs Solexa....

Starship giant transposable elements cluster by host taxonomy using k-mer-based phylogenetics. #TransposableElements #TEs #Kmer #Phylogenetics #Genomics #Bioinformatics #G3 🧬 🖥️
academic.oup.com/g3journal/ad...

The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers - Genome Biology Background Transcriptome sequencing (RNA-seq) is a powerful technology for gene expression profiling. Selection of optimal parameters for cDNA library generation is crucial for acquisition of…

The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers. #RNAseq #PCRduplication #Benchmarking #Genomics #GenomeBiology
genomebiology.biomedcentral.com/articles/10....

Comparative assessment of the Sikun 2000 sequencing platform for whole genome sequencing - Scientific Reports Scientific Reports - Comparative assessment of the Sikun 2000 sequencing platform for whole genome sequencing

Comparative assessment of the Sikun 2000 sequencing platform for whole genome sequencing. #ShortRead #Sequencer #ScientificData
www.nature.com/articles/s41...

Flexible, production-scale, human whole genome sequencing on a benchtop sequencer - BMC Genomics Human whole-genome sequencing (hWGS) provides comprehensive genomic information that can help guide research in disease prevention and treatment. Recent advancements in sequencing technology have…

Flexible, production-scale, human whole genome sequencing on a benchtop sequencer. #WGS #GenomeSequencing #NGS #Sequencing #Genomics #ElementBiosciences #Aviti ‪@elembio.bsky.social‬ 🧬🧪
bmcgenomics.biomedcentral.com/articles/10....

That’s a wrap on our NEB RNA-seq Library Prep Lab Course! 🧪🔬
Big thanks to everyone who took part and made the course a success! 👏
Special thanks to Max Fritsch & Michael Skelly, from New England Biolabs 🦋, for their continued support!

Next course on RNA-seq data 👇
genomics.ed.ac.uk/event/rna-se...

Want to get to grips with RNA-seq data? Join our online RNA-seq Data Analysis workshop from 16–19 June 2025!
✅ Perform differential expression analysis
✅ Use tools like STAR, DESeq2 & more
🖥️ Hands-on, expert-led, and beginner-friendly.
📅register now: genomics.ed.ac.uk/event/rna-se...

📣 We still have a couple of spots left in our online training courses next week!

🧬 Linux for Genomics (9–10 June)
👉 genomics.ed.ac.uk/event/introd...

📊 R for Biologists (11–13 June)
👉 genomics.ed.ac.uk/event/r-for-...

Don’t miss out - last places available!

📣 There are still a few places available on our upcoming #RNASeq library prep Course, running next week, 28–29 May, at Edinburgh Genomics. 🧬🧪

⏳ Don’t miss out – registration closes soon!
👉 genomics.ed.ac.uk/event/rna-li...

#Sequencing #Genomics #RNAseq #LabTraining

🔬 That’s a wrap on our Metabarcoding & Metagenomics workshop!
4 days of hands-on tutorials, microbiome insights, and plenty of Qiime2, NanoClust, and HUMAnN action 🧫💻
Huge thanks to our amazing participants & instructors!

#bioinformatics #metagenomics #EdGenTraining

It was great to welcome colleagues from the
Sarawak Infectious Disease Centre this week!

🔬They visited Edinburgh Genomics, with productive discussion around genomics infrastructure, data generation, and long-read sequencing

🌏 Always a pleasure to connect with international teams driving innovation

Join our 2-day RNA Library Preparation Lab Course at Edinburgh Genomics:

📅 28–29 May 2025
📍 Ashworth Labs, University of Edinburgh
🧪 Use @NEBiolabs NEBNext UltraExpress kits
🧬 Option to bring your own sample!

👉 genomics.ed.ac.uk/event/rna-li...

📸 See our last course in action!

🚨 Our Intro to #Python course starts next week and there’s still space!

🧬 Perfect for #biologists & #genomic scientists
💻 🖥️Learn to automate tasks, analyse data & build #bioinformatics pipelines
📍 In-person

📅 Plus #R & #Linux courses in June!
🔗 Sign up: genomics.ed.ac.uk/training

That’s a wrap on our first-ever Full Length 16S rRNA @pacbio.bsky.social Sequencing & Bioinformatics course! 🧪💻

From lab bench to species-level insight, participants processed their own data through QC, DADA2, taxonomic annotation & more, to create figures like this! 🧬👇

We’ve just wrapped up the lab part of our new Full Length 16S rRNA @pacbio.bsky.social course 🧪🧬

Next week, we’ll take the data into bioinformatics—giving participants full end-to-end insight into the workflow. 🖥️

Join a future lab course 👉 genomics.ed.ac.uk/event/rna-li...

#Genomics #PacBio #16S

Last week, we were delighted to host a seminar with Tushar from Scale Biosciences who shared exciting insights into their latest technologies and protocols for #SingleCell sequencing

Great to see so much interest and discussion around innovation in this fast-moving field!

That’s a wrap on last week’s #Snakemake ! Thank you to our participants for their enthusiasm—hope you’re ready to supercharge your workflows! 🐍🖥️🧬

Next week 16S lab and bioinformatics: genomics.ed.ac.uk/event/full-l...

Then long read bioinformatics April 28 - May 1
genomics.ed.ac.uk/event/introd...

Why does this matter?

Choosing the right extraction method is essential for getting high-quality sequencing data. Our team has tested these approaches to ensure the best possible results!

Have an extraction method you swear by? Let’s discuss!👇#Genomics #DNAExtraction

🧵5/5

⚠️ CRUCIAL WARNING ⚠️

❌ DO NOT use phenol-chloroform extractions if you're planning to sequence with PacBio - it can interfere with sequencing chemistry and lead to poor results.

@pacbio.bsky.social

🧵4/5

Long-read sequencing (ONT/PacBio) needs high molecular weight (HMW) DNA for optimal read length.

Our top choices:
🔹 NEB Monarch HMW DNA
🔹 promega Wizard HMW DNA

@nebiolabs.bsky.social @promegacorporation.bsky.social @promegauk.bsky.social

🧵3/5

Short-read sequencing (Illumina) requires high-quality, fragmented DNA or RNA.

Our recommendations:
🔹 DNA (general): Qiagen PowerSoil Pro
🔹 DNA (plant samples): Qiagen DNeasy Plant
🔹 RNA: Qiagen RNeasy

@qiagen.bsky.social

🧵2/5