Darius Valevicius

I felt like there must be some unspoken rule not to talk about it?

I just attended a conference that involved a fair percentage of really good work, mostly in the keynotes, but around 70-80% of the poster and symposia results would be completely voided if any multiple comparisons correction was used. No one seemed the least bit worried about it!

In the latter theory as far as I can gather the learning is "done by" distributed cortical regions? E.g. the metabolic cost/benefit which would constitute reward/aversion is computed by medial PFC, insula etc. (which seems like an extremely computationally intensive task)

In Pksp's model, behavioral learning "bottoms out" in homeostatic error signals generated in the PAG... It's not dissimilar from the predictive brain theory of LFB except that error signals (which == affects) bottom out in high-level heuristics rather than optimizations of metabolic cost and benefit

'What is doing the learning' in terms of brain circuits or conceptually?

This seems in line with Panksepp's hypothesis of dopamine/the MFB as a general-purpose system for motivated behaviour right?

I also recall reading a critique (from Solms?) of the RPE hypothesis that the whole brain responds to RPEs, so the VTA was never very special in that regard to begin with

Little view of Montreal at dusk yesterday

Or a discord server for people wanting to talk shop in their spare time? If some folks show interest I can throw one together

I felt the part about scientific conversations taking the backseat to logistical and "academic lifestyle" conversations. Honestly the latter bores me to tears most of the time ;-; time to start a journal club I guess?

That was an initial thought I had, that EDA spiking/sudomotor nerve firing might correlate with the phase of low frequency BOLD oscillations. But I wonder why that would be?

Also @blaisefrederick.bsky.social

Breath holding in anticipation? Or neuronally induced anticipation signal? Why does the EDA spike seem to trigger/coincide with a crash in GS? Paging @danielhandwerker.bsky.social @practicalfmri.bsky.social

Paper in question: doi.org/10.1016/j.ne...

Physio question for #neuroskyence: This figure shows that global BOLD signal is already increasing before the onset of electrodermal spikes (t=0), and falls rapidly afterwards. I get the same pattern in my dataset (also for event-related analysis, GS peaks at t=0). What are potential explanations?

I guess that is one way to put it 😅

Not exactly sure how to put this but I guess I'm wondering how much of a disconnect there is between the phenomenology of peripheral vision and how we think about it conceptually, and how that's affected by mistaking beliefs for percepts

Do we know how much is "filling in" and how much is just beliefs about what ought to be there? I recall someone arguing that the blind spot phenomenon was proof of top down predictive processing. But to me, it just registers as an absence or lack, not that anything has been "filled in".

Dovetails well with this recent work: bsky.app/profile/tsbo...

"The findings support our reframing of arousal from a discrete, one-dimensional state to a structured, organism-wide process that continuously unfolds in an abstract multidimensional mathematical space."

Has Platonism gone too far?

Cool paper though :)

I noticed a jump from mixed selectivity to multifunctionality in this discussion - does a complex tuning curve imply a node with multiple functions? Or a node with a function that is recruited in multiple contexts?

"The Trading Game" is great pop econ. But yeah this balance is something that's been on my mind a lot, all my aspirations to help people by understanding the brain / the psyche start to pale the more broke we all get...

Could be a motor metaphor, e.g. when feeling "up" you feel buoyant (I know you'll appreciate that term) and have a spring in your step, when feeling "down" you can't seem to muster up the energy to rise out of bed?

Neurologically it must have something to do with SEEKING system tone..?

And these days we also use it to refer to a non-symptomatic feeling/emotion 😛

Btw, the term "autism" was originally coined to refer to a symptom of schizophrenia, as recently as the 1910s. Big semantic shift!

Thanks for reaching out to include us! An intimidating but fun opportunity :)

Which in my code is motivated by my need to minimize cognitive load, and in brains I imagine is motivated by the need to conserve resources by minimizing distances for frequent signals

This is always intuitive to me as someone who codes a lot (particularly for video games). Even if I write "spaghetti code" where many scripts are obliged to reference each other, there's still a method to the madness and individual scripts/objects maintain as much modularity as I can give them...

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Thanks for the tip! It seems like this explanation might be the case, though I'll have to wait for the rest of the data to be sure.

I would liken this to the painting style where you make a very detailed underpainting or sketch which results in the top coat basically being paint-by-numbers :)

Another strat that I sometimes manage to use is to create an outline that has a bullet point for every single idea, statement, or thought, and edit that + arrange it into a logical sequence and hierarchy before turning it all into prose at the end.