Nick Johnson MD

Nguyen et al: Ability of a Composite Brain Magnetic Resonance Imaging Score to Predict Neurologic Outcomes in Survivors of Out-Of-Hospital Cardiac Arrest

Link: link.springer.com/ar...

@neurocritical #neurocritcare

Figure 2. Oxygen Exposure and Arterial Oxygenation by Treatment Group in Patients With Enhanced Data Collection

Conservative oxygen therapy with a target SpO2 of 90% did not reduce 90-day all-cause mortality compared to usual oxygen therapy in mechanically ventilated adult patients.

#CCR25 @criticalcarereviews.com

https://ja.ma/4kG5gWK

Slightly late, and to be updated with the results of today's TTM2 biomarker results, today's Paper of the Day is:

Biomarkers for neuroprognostication after out-of-hospital cardiac arrest

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Figure 2. Total Protein and Calories

Augmenting enteral protein did not improve outcomes for critically ill patients compared with standard protein levels in the intensive care setting.

#CCR25 @criticalcarereviews.com

https://ja.ma/4mUjFQr

In children with septic shock and no known cardiac dysfunction, starting treatment with norepinephrine rather than epinephrine was associated with lower 30-day mortality.

#CCR25 #MedSky

ja.ma/4kXryTp

Intravenous hydrocortisone was associated with a reduced need for new kidney replacement therapy in patients with septic shock.

#CCR25 #MedSky

ja.ma/3SLC3xg

I think that could work just fine, especially given the kinetics of NfL compared w some of the other biomarkers, some of which peak early enough that they may not help after 72h.

Impact of initial jugular vein insertion site selection for central venous catheter placement on hemodialysis catheter complications This study evaluated the impact of choosing the right versus left internal jugular vein (IJV) for initial central venous catheter (CVC) placement on h…

Finally some evidence to support a concept we’ve taught for years. Save the right IJ for when it’s absolutely necessary (eg, dialysis, ECMO). Kudos to the authors.

www.sciencedirect.com/science/arti...

Figure 2. Cumulative Incidence Plot for Time From Randomization to Successful Extubation

In critically ill patients, neither dexmedetomidine nor clonidine was superior to propofol in reducing time to successful extubation. #ATS2025

https://ja.ma/3Sw1K4Z

🚨The Preprint Draft 2025 ILCOR CoSTR is posted🚨

An incredible amount of work goes into developing this document, which will inform practice guidelines worldwide. Proud to be a small part, but mostly impressed with everyone’s work after peeking behind the curtains.

ilcor.org/publications...

Not in this dataset, but we are currently doing a randomized trial of SGA vs BVM placed by FF/EMTs for OHCA that will
include some fairly detailed ventilation meaurements in both arms. Different question
somewhat, but we hope helpful: clinicaltrials.gov/study/NCT059...

Really cool study led by David Murphy on "apnea interval" - the interruption in ventilation due to intubation attempt during CPR. TL;DR: Shorter apnea interval associated with favorable outcomes.

sciencedirect.com/science/articl…

agree w others. benefit, if any, is not immediate, but a small reduction in long-term neurological sequelae. seems that propensity to use depends on ease of access to appropriate chamber.

Position paper on physiology & nomenclature of dual circulation in VA #ECMO in adults
🩸retrograde blood flow & dual circulation
📖 historical & recommended nomenclature
🩸dynamic nature of mixing point
💨 differential O2 & CO2
🩺 clinical management
💨 hypoxemia & hyper/hypocapnia
#FOAMcc
🔓 rdcu.be/d0KSQ

Defibrillation and refractory ventricular fibrillation Of patients with out-of-hospital cardiac arrest (OHCA) presenting in ventricular fibrillation (VF), the majority require multiple shocks.1 Guidelines recom

Does VF on consecutive rhythm checks mean refractory or recurrent VF?

In this analysis of data from cases in the ARREST registry out of Amsterdam, only 5% (n=22) of cases remained in refractory VF after 3 shocks.

#emimcc

academic.oup.com/eurheartj/ad...

Next up! Looking at long term outcomes after the TTM 24 vs 48hr trial. #emimcc #ReSS24 @pulmcrit.bsky.social @tscquizzato.bsky.social @nickjohnsonmd.bsky.social @joshkimbre.bsky.social

Late-breaking science session #ReSs24! First up the PROTECT trial examining ceftriaxone PPx after cardiac arrest @nickjohnsonmd.bsky.social @pulmtoilet.bsky.social @imcrit.bsky.social @pulmcrit.bsky.social

Fantastic evening at the #ReSS24 Early Career Networking Event in Chicago! Great to reconnect with friends and meet so many talented resuscitation scientists!

@americanheart.bsky.social @nickjohnsonmd.bsky.social @sarahmperman.bsky.social

Not exactly what you want but at least a little lower threshold for potassium supplementation after cardiac surgery - 3.5 v 4.5

pubmed.ncbi.nlm.nih.gov/39215972/

a cartoon of a man clapping in front of a computer screen . ALT: a cartoon of a man clapping in front of a computer screen .

New ILCOR cardiac arrest evidence synthesis and recommendations just dropped! New recs on BP goals and seizure PPx post arrest among others. Take a look here and can comment. #emimcc @nickjohnsonmd.bsky.social @pulmcrit.bsky.social @nickmark.bsky.social @ercresus.bsky.social

2024 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pedi... This is the eighth annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatm...

ILCOR has published our latest Consensus on Science with Treatment Recommendations (CoSTR), outlining vital updates in resuscitation science and post-cardiac arrest care.

Check it out here: www.ahajournals.org/doi/10.1161/...

Looking for medical professionals to follow? Here are two (non-exhaustive) starter packs 🩺🧪 med sky

Round 1
go.bsky.app/Qg2TA9p

Round 2
go.bsky.app/9ziyYqt

Feel free to let me know others to add and they will be added to the second (until it maxes out at 150)

Thank you! And many thanks for these awesome lists!!

Oh hey!

Welcome to everyone new to Bluesky! Here are 4 (illustrated) steps you can take to make your experience here more pleasant than what you left behind on X and/or Threads. A 🧵

Hello!!!! Good to see you and so many others over here.

For those I haven’t met: Nick, EM-Intensivist from Seattle.

Well, I figured it was time (or perhaps long overdue) to explore a different platform. Good to see you all!!

Wonderful to see you!!