Patrick Mulholland (He/Him)

Follow these links to apply to present and join the alcohol neuroscience research community!

GRS (Trainee pre-meeting, Feb 21-22, 2026): tinyurl.com/35zf3wte
GRC (Main meeting immediately following, Feb 22-27, 2026): tinyurl.com/44z957ve

Apply now for the Alcohol & the Nervous System GRS, Feb 21-22, 2026!

The GRS kicks off the GRC, giving early-career scientists the perfect platform to launch into a week of cutting-edge science. Submit your abstracts to both by Oct 10th for talk consideration! #alcoholGRC2026 #alcoholGRS2026

We are looking forward to the 2026 #Alcohol GRC in Ventura, CA! The main meeting starts Feb 22, 2026 (GRS Feb 21-22). For both, we will be selecting additional invited talks from the submitted abstracts. For consideration, submit your abstract by Oct 10! #alcoholGRC2026 #alcoholGRS2026

Voluntary wheel-running reduces harmful drinking in a genetic risk model for drinking to intoxication Physical activity (PA) may provide an effective and equitable treatment option for addressing the harm associated with Alcohol Use Disorders (AUDs). W…

Voluntary wheel-running reduces harmful drinking in a genetic risk model for drinking to intoxication #alcoholawareness #alcohol
@angelaozburn.bsky.social
sciencedirect.com/science/arti...

A Conceptual Framework for the Intersection of Hyperalgesia and Hyperkatifeia in Alcohol Addiction Alcohol use disorder is a chronically relapsing disorder that is characterized by compulsive drug seeking and is hypothesized to result from multiple …

NIAAA Director Dr. Koob's publication now online - A Conceptual Framework for the Intersection of Hyperalgesia and Hyperkatifeia in #Alcohol Addiction #alcoholawareness www.sciencedirect.com/science/arti...

Alcohol, aging, and the gut microbiome: Intersections of immunity, barrier dysfunction, and disease Alcohol consumption exerts complex, dose- and context-dependent effects on human health, particularly by influencing the gut microbiome, intestinal ba…

Alcohol, aging, and the gut microbiome: Intersections of immunity, barrier dysfunction, and disease @cristinallorente.bsky.social #alcoholawareness
www.sciencedirect.com/science/arti...

Persistent inflammation does not promote aversion-resistant binge-like alcohol drinking in rats Chronic pain is a leading cause of disability, significantly decreases quality of life, and is highly co-morbid with substance use disorders, includin…

Persistent inflammation does not promote aversion-resistant binge-like #alcohol drinking in rats @jmoronconcepcion.bsky.social #alcoholawareness www.sciencedirect.com/science/arti...

The Majchrowicz binge model of alcohol dependence: A valid model for comparing male and female rats Alcohol use disorders (AUD) among women have steadily risen over the past decade. This increase is due in part to increased rates of drinking among so…

The Majchrowicz binge model of #alcohol dependence: A valid model for comparing male and female rats @nixonlab.bsky.social www.sciencedirect.com/science/arti...

Alcohol use disorder exacerbates clinical and vascular risks differentially in psychiatric disorders Alcohol Use Disorder (AUD) is a major public health concern with detrimental effects on cognitive and neurological function, yet its impact on psychia…

Just published: #Alcohol use disorder exacerbates clinical and vascular risks differentially in psychiatric disorders sciencedirect.com/science/arti...

Explaining increased efficacy of naltrexone in the treatment of alcohol dependent patients with a family history of alcohol use disorder: A systematic review on the role of reward sensitivity and swee... A positive family history of alcohol use disorder (FHA+) is one of the strongest risk factors for developing alcohol use disorder (AUD) compared. Impo…

Just Published: Explaining increased efficacy of naltrexone in the treatment of #alcohol dependent patients with a family history of AUD: A systematic review on the role of reward sensitivity and sweet liking www.sciencedirect.com/science/arti...

Effect of high mobility group box 1 pathway inhibition on gene expression in the prefrontal cortex of mice exposed to alcohol The high mobility group box 1 (HMGB1) pathway plays a pivotal role in the development of alcohol-induced brain injury. Glycyrrhizinic acid (GlyA) is w…

Just Published: Effect of high mobility group box 1 pathway inhibition on gene expression in the prefrontal cortex of mice exposed to #alcohol www.sciencedirect.com/science/arti...

Integrating TWAS and GWAS identifies gut microbiota–immune interactions to alcohol dependence genetics in European sample Alcohol dependence (AD) is a global public health concern with strong genetic characteristics. The purpose of this study was to explore the underlying…

Just Published: Integrating TWAS and GWAS identifies gut microbiota–immune interactions to #alcohol dependence genetics in European sample www.sciencedirect.com/science/arti...

Alcohol consumption during early adulthood increases the vulnerability of locus coeruleus neurons and amyloid beta pathology in female APP/PS1 mice Alcohol use disorder is the most common substance misuse disorder and Alzheimer's disease (AD) is the most common neurodegenerative disease. Evidence …

Just Published: #Alcohol consumption during early adulthood increases the vulnerability of locus coeruleus neurons and amyloid beta pathology in female APP/PS1 mice #AlcoholAwareness sciencedirect.com/science/arti...

a man applauds with the words way to go super proud of you behind him ALT: a man applauds with the words way to go super proud of you behind him

Absolutely crushing it, congrats Kathy!!!!

First the #RSA 3-min thesis inaugural winner and now the Gordis Award for @kathylindquist.bsky.social #proud-mentor #rsa2025 #rsa_isbra2025 @drjrink.bsky.social

Hey #alcohol researchers, what are non-NIH funding mechanisms to support alcohol research? Please share any information #rsa2025 #rsa_isbra2025

Alcohol research community: thank you for your submissions to #Alcohol - we are excited to share that our Impact Factor has climbed to 2.9, our highest IF to date #rsa2025

@dougmat-uwec.bsky.social

Congrats to @kathylindquist.bsky.social for winning the 3MT competition for preclinical students - way to go, Kathy!!! @drjrink.bsky.social

Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system - PubMed High-intensity alcohol drinking during binge episodes contributes to the socioeconomic burden created by alcohol use disorders (AUDs), and nociceptin receptor (NOP) antagonists have emerged as a promi...

oh hey, this paper is out now!

Led by JR Haun, former Kash lab postdoc!

pubmed.ncbi.nlm.nih.gov/40153436/

Defending soon? Come postdoc with us - MUSC is a great place to prepare you for your next career move, in or outside of academia!

The Charleston Alcohol Research Center has an opening for a #postdoctoral fellowship on the #NIAAA T32 training grant - please spread the word and contact me if interested in working in beautiful Charleston, SC @drjrink.bsky.social

Here is a link to our DIY balance arm for fiber #photometry recordings in freely moving mice @drjrink.bsky.social
github.com/Patrick-Mulh...

These types of grants were removed from the discussion list for AA-4 on the morning of review. It’s unclear to me if the SRO/PO will provide the written critique. My guess is that you won’t receive anything until an official review. Hope that happens for you and the others very soon

Donate to Kathy Needs Your Help After Apartment Fire, organized by Patrick Mulholland A graduate student in the Department of Neuroscience (Kathy L.) at MUSC … Patrick Mulholland needs your support for Kathy Needs Your Help After Apartment Fire

Dear science community, an amazing grad student with @drjrink.bsky.social and I lost her belongings in an apartment fire this morning. She and her dog are safe but needs your help. Please consider donating

www.gofundme.com/f/kathy-need...

Flat 15% indirect costs across all grants (notes this will work because only 3 places - MIT, UMich, UAB - ever REFUSED a grant for lower than expected previous indirects). Impacts of this cut will presumably destroy research - current indirects are ~50%+

grants.nih.gov/grants/guide...

While I agree that UMAPs can be problematic, I also think that statisticians have a lot to answer for with regard to the general debasement of modern science towards p-values instead of critical thinking and model building. That has been far more damaging than a couple of silly plots.

Sex and Gender Differences in Alcohol Use Disorder: Quo Vadis?

Just published in our special issue on #Sex and #Gender Differences in #Alcohol Use Disorder: Quo Vadis?
sciencedirect.com/science/arti...

Our February issue is now online #alcohol #drunkorexia #PTSD #stress #ADHD #AUD

sciencedirect.com/journal/alco...

Just published: Understanding #drunkorexia behaviors among college students sciencedirect.com/science/arti...

Even 1 drink a day elevates your cancer risk – an expert on how alcohol affects the body breaks down a new government report The government linked alcohol with seven types of cancers, prompting the US surgeon general to call for warning labels on beer, wine and liquor.

The Conversation asked me to share my thoughts on the new U.S. Surgeon General Advisory around alcohol and cancer & to break down some of the science in an accessible way. Check it out here: theconversation.com/even-1-drink...