JAMA Internal Medicine

Among medical students with disabilities, 12.4% reported experiencing discrimination, with the highest rates among those with chronic illness, motor or sensory disabilities, and multiple disabilities. ja.ma/4lQpkpW

Visual Abstract

A nurse-led, interprofessional family support intervention in ICUs showed improvements in family satisfaction, communication quality, and cognitive and emotional support for families of critically ill patients. ja.ma/458Xe2a

Germicidal UV Light and Incidence of Acute Respiratory Infection in Long-Term Care for Older Adults

Germicidal UV appliances in common areas of long-term care facilities did not significantly reduce the incidence rate of acute respiratory infections per zone per cycle. ja.ma/45cwC05

Germicidal UV appliances in common areas of long-term care facilities did not significantly reduce the incidence rate of acute respiratory infections per zone per cycle. ja.ma/4lJZi7A

Patient Page

Most viewed this week from JAMA Internal Medicine: Patient Page covers #GLP1 weight-loss medications, focusing on food craving reduction, blood glucose control, dietary strategies, exercise for muscle retention, and lifestyle changes to prevent weight regain.

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Patient Page

Most viewed this week from JAMA Internal Medicine: Patient Page covers #GLP1 weight-loss medications, focusing on food craving reduction, blood glucose control, dietary strategies, exercise for muscle retention, and lifestyle changes to prevent weight regain.

ja.ma/4lN9dJS

Figure. Cumulative Hazard Curves of Patients Receiving Outpatient Parenteral Antimicrobial Therapy (OPAT) Through Midline Catheters, by Receipt of Vancomycin

Vancomycin in midline catheters for outpatient therapy was associated with increased risks of bloodstream infections, venous thromboembolism, and device failure compared to other treatments. ja.ma/46nSmbH

Figure. Publicly Funded Vitamin D Tests Performed per 1000 Patient Visits per Month From April 2005 to March 2024

Implementing criteria-based testing for vitamin D in Ontario reduced testing initially, but the volume of tests returned to pre-policy levels over the following 14 years.

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Figure. Association of Life Expectancy and Incarceration Rate Stratified By Social Vulnerability Index (SVI)

Neighborhood incarceration rates were associated with lower life expectancy, with the most incarcerated neighborhoods experiencing the largest reductions in life expectancy.

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Isotretinoin under Risk Evaluation and Mitigation Strategy reduced pregnancy incidence by 70% to 80% compared to topical retinoids. ja.ma/4o3Zwbc

Illustration

From @jama.com: Approximately 18.6 million people worldwide are affected by a diabetic foot ulcer each year.

This Review summarizes the epidemiology, pathophysiology, diagnosis, treatment, and prevention of diabetic foot ulcers.

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This JAMA Internal Medicine patient page covers #GLP1 weight-loss medications, focusing on food craving reduction, blood glucose control, dietary strategies, exercise for muscle retention, and lifestyle changes to prevent weight regain. ja.ma/4lHVzaR

Figure 1. Changes in Coding Intensity Before and After the Implementation of the Patient Driven Payment Model (PDPM) in Hospitals and Skilled Nursing Facilities (SNFs)

The Patient Driven Payment Model was associated with increased coding intensity and Medicare expenditures in skilled nursing facilities without affecting rehospitalization or mortality rates. ja.ma/3UpedYU

Figure. Estimated Spending Under the Status Quo vs Under Medicare Price Negotiation for the Top 25 Anticancer Drugs by 2022 Gross Spending

Viewpoint: While the Inflation Reduction Act may initially lower anticancer drug costs, long-term spending could increase due to improved affordability and mandatory coverage.

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Figure. Distributions of Time Intervals From Cancer-Related Diagnostic Signal toWorkup Initiation andWorkup Completion in Patients With Missed Opportunities

A digital quality measure for advanced-stage cancer diagnoses was associated with higher rates of missed diagnostic opportunities.

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Patient Page

Most viewed this week from JAMA Internal Medicine: Patient Page covers #GLP1 weight-loss medications, focusing on food craving reduction, blood glucose control, dietary strategies, exercise for muscle retention, & lifestyle changes to prevent weight regain.

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From @jama.com: Early-onset gastrointestinal cancers are among the largest subset of early-onset cancers globally.

This JAMA Review summarizes current evidence on early-onset gastrointestinal cancers.

https://ja.ma/3TISsDc

Patient Page

Most viewed this week from JAMA Internal Medicine: Patient Page covers #GLP1 weight-loss medications, focusing on food craving reduction, blood glucose control, dietary strategies, exercise for muscle retention, & lifestyle changes to prevent weight regain.

https://ja.ma/4eSYMSc

Table. Recommendations for Breast Cancer Screening and Patient Navigation for Breast and Cervical Cancer Screeninga

Viewpoint: The Women's Preventive Services Initiative recommends expanded coverage and patient navigation for breast cancer screening to improve effectiveness and accessibility.

https://ja.ma/4lEbQO6

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From @jama.com: Global prevalence of chronic kidney disease (CKD) is approximately 9%, and patients with CKD are at increased risk of morbidity and mortality.

This JAMA Clinical Guidelines Synopsis summarizes the 2024 KDIGO recommendations for managing CKD in adults. https://ja.ma/3UeUX09

Figure. 12-Lead Electrocardiogram (ECG) Before and After Treatment

This case report describes a man in his 60s who presented with a 3-day history of low-grade, intermittent fever, myalgia, and headache, along with episodes of blurred vision and recurrent syncope. https://ja.ma/4ltguy1

Figure. Network Diagram of Randomized Clinical Trials That Have Tested an Approved Next-In-Class Anticancer Drug Against an In-Class Comparator (N = 27)

Among FDA anticancer drug approvals from 2009 to 2020, only 27 next-in-class drugs had direct randomized clinical trial comparisons with first-in-class drugs. https://ja.ma/3Gs6k1J

Read the Patient Page “I Am Taking a GLP-1 Weight-Loss Medication—What Should I Know?” jamanetwork.com/journals/jam...

Read the Clinical Insights article “Integrating Diet and Physical Activity When Prescribing GLP-1s—Lifestyle Factors Remain Crucial.” jamanetwork.com/journals/jam...

5 things doctors want you to know before you start taking a GLP-1 There’s a perception that Ozempic, Wegovy and Zepbound are all you need to live a healthier life. But diet and exercise still matter, doctors say.

GLP-1s are increasingly being prescribed. Two recent JAMA Internal Medicine articles cover what both clinicians and patients should know about these medications.

The @washingtonpost.com covered these articles: www.washingtonpost.com/wellness/202... 🧵

Figure. Integrating Nutrition and Physical Activity with GLP-1 and Dual Receptor Agonist Therapy

Integrating lifestyle factors like diet and physical activity with #GLP1 receptor agonists is essential for managing symptoms, maintaining nutrition, preserving lean mass, and promoting regular physical activity.

https://ja.ma/4lUZPU5

Figure 1. Pathophysiology of Male Lower Urinary Tract Symptoms

From @jama.com: Lower urinary tract symptoms are common among men and are usually caused by BPH, overactive bladder detrusor, or both.

This Narrative Review summarizes the epidemiology, pathophysiology, diagnosis, and management of these symptoms.

https://ja.ma/3UaZVLn

Metformin on Time to Sustained Recovery in Adults With COVID-19

In adults with acute mild to moderate #COVID19, metformin did not shorten recovery time compared to placebo, with similar median times to symptom resolution in both groups. https://ja.ma/4nPASuT BramanteCarolyn

📣 Heading to #ENDO2025? Check out our page created for attendees.

➡️ Find recent articles and podcasts
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➡️ Get information For Authors on @jama.com, @jamainternalmed.com, and @jamanetworkopen.com.

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This JAMA patient page covers #GLP1 weight-loss medications, focusing on food craving reduction, blood glucose control, dietary strategies, exercise for muscle retention, and lifestyle changes to prevent weight regain.

ja.ma/4lpkb7T