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Thomas Jaki

@thomasjaki.bsky.social

Professor of Statistics at University of Regensburg and University of Cambridge

239 Followers  |  105 Following  |  6 Posts  |  Joined: 25.10.2024  |  1.6897

Latest posts by thomasjaki.bsky.social on Bluesky

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Incorporating historic information to further improve power when conducting Bayesian information borrowing in basket trials ABSTRACT. In basket trials a single therapeutic treatment is tested on several patient populations simultaneously, each of which forming a basket, where pa

Incorporating historic information to further improve power when conducting Bayesian information borrowing in basket trials

academic.oup.com/biostatistic...

23.06.2025 14:25 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Design of platform trials with a change in the control treatment arm ABSTRACT. Platform trials are an efficient way of testing multiple treatments. We consider platform trials where, if a treatment is found to be superior to

Design of platform trials with a change in the control treatment arm

academic.oup.com/biometrics/a...

23.06.2025 14:24 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Photo of speakers from day 1, all smiling and looking at camera.

Photo of speakers from day 1, all smiling and looking at camera.

Photo of speaker, Christina Yap, giving talk.

Photo of speaker, Christina Yap, giving talk.

Photo of speakers of day 2, all smiling and looking at camera.

Photo of speakers of day 2, all smiling and looking at camera.

Photo of Pavel Mozgunov delivering talk.

Photo of Pavel Mozgunov delivering talk.

Fantastic two days of stimulating talks and discussions at our Workshop on Adaptive and Bayesian Designs in Real Trials, where statisticians, clinicians and patients have shared their experiences of #ClinicalTrials.

Thanks to all our speakers and all those who attended.

06.06.2025 15:29 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

A thought provoking event. Glad I could participate.

25.04.2025 05:41 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Photo of Stef Baas giving talk, with presentation screen behind him.

Photo of Stef Baas giving talk, with presentation screen behind him.

Photo of Gianmarco Caruso giving talk, with presentation screen behind him.

Photo of Gianmarco Caruso giving talk, with presentation screen behind him.

Photo of James Willard giving talk, with presentation screen behind him.

Photo of James Willard giving talk, with presentation screen behind him.

(1/2) Another action packed day at the workshop on Adaptive Designs and Multiple Testing Procedures in Regensburg, with great talks from BSU researchers and PhD students - Gianmarco Caruso, Stef Baas and James Willard.

27.02.2025 13:50 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Photo of Connor Fitchett giving a presentation with projector screen of slide behind them.

Photo of Connor Fitchett giving a presentation with projector screen of slide behind them.

Photo of Weishi Chen giving a presentation with projector screen of slide behind them.

Photo of Weishi Chen giving a presentation with projector screen of slide behind them.

David Robertson and Thomas Jaki are organising a workshop on Adaptive Designs and Multiple Testing Procedures, happening today and tomorrow in Regensburg.

admtp.github.io/ADMTP2025/

BSU PhD students, Connor Fitchett and Weishi Chen, have presented today.

26.02.2025 15:14 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
PhD Opportunities | MRC Biostatistics Unit shutterstock_337964138_students_small.jpg We actively support equality, diversity and inclusion and encourage applications from all sections of society. We are committed to widening participation in ...

The deadline to apply for a @mrc-bsu.bsky.social PhD studentship has been EXTENDED to March 27, 2025! πŸ—“οΈβœ¨

Explore the exciting PhD projects available here: www.mrc-bsu.cam.ac.uk/phd-opportun... πŸ”πŸ“š

🌟 Special shoutout to the project by @thomasjaki.bsky.social and myself πŸ‘Ό

17.02.2025 08:24 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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I suspect many of us need to hear this today. @charliemackesy1.bsky.social

15.02.2025 20:04 β€” πŸ‘ 58    πŸ” 8    πŸ’¬ 3    πŸ“Œ 1
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Einfache Testverfahren zur ÜberprΓΌfung der Aussagekraft von Bioresonanz-basierten medizinischen Befunden β€” der LeberkΓ€se-Test - Allergo Journal Allergo Journal - Trotz aller AufklΓ€rungsarbeit wird die Bioresonanz weiter benutzt. Seit einigen Jahren sind modifizierte GerΓ€te auf dem Markt, die auch in ReformhΓ€usern zum Einsatz...

Bioresonanz. Die Γ„lteren von euch erinnern sich ja daran, dass ich diese Studie so mag.

link.springer.com/article/10.1...

Warum ist diese Studie so toll?

Weil keine andere Studie Bioresonanz an Menschen, LeberkΓ€se(!), einem feuchten Tuch sowie einem Leichnam(!) ausprobiert hat.

Ein paar Zitate:

02.12.2024 20:20 β€” πŸ‘ 553    πŸ” 190    πŸ’¬ 45    πŸ“Œ 19
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Designs for sequences of early phase (modular) studies at University of Cambridge on FindAPhD.com PhD Project - Designs for sequences of early phase (modular) studies at University of Cambridge, listed on FindAPhD.com

I am looking for a PhD student in Medical Statistics. This project aims to develop new methods for design of early phase trials starting from monotherapy and progressing into combinations. More details are in the link. Feel free to contact me if any questions. www.findaphd.com/phds/project...

26.11.2024 11:53 β€” πŸ‘ 6    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Interested in learning about Bayesian Clinical Trials? We are running a 2-day short course (24th-25th February 2025) on the topic directly prior to the Adaptive Designs and Multiple Testing Procedures Workshop.

To register and more information visit admtp.github.io/ADMTP2025/co...

25.11.2024 18:35 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Statistical Analysis with Missing Data Using Multiple Imputation | LSHTM

Our 3 day short course @lshtm.bsky.social on multiple imputation for missing data using R is now open for registration. 17-19 June 2025. This year the course will be online only. More info here: www.lshtm.ac.uk/study/course...

21.11.2024 07:41 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1
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A seamless Phase I/II platform design with a time-to-event efficacy endpoint for potential COVID-19 therapies - Thomas Jaki, Helen Barnett, Andrew Titman, Pavel Mozgunov, 2024 In the search for effective treatments for COVID-19, the initial emphasis has been on re-purposed treatments. To maximize the chances of finding successful trea...

Our design for the early phase platform AGILE for treatments for COVID-19 has just been published.

journals.sagepub.com/doi/10.1177/...

19.11.2024 11:54 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Confidence intervals for adaptive trial designs II: Case study and practical guidance In adaptive clinical trials, the conventional confidence interval (CI) for a treatment effect is prone to undesirable properties such as undercoverage and potential inconsistency with the final hypoth...

Our part 2 series paper in peer review...

Confidence intervals for adaptive trial designs II: Case study and practical guidance

arxiv.org/abs/2411.08771

14.11.2024 21:18 β€” πŸ‘ 8    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Confidence intervals for adaptive trial designs I: A methodological review Regulatory guidance notes the need for caution in the interpretation of confidence intervals (CIs) constructed during and after an adaptive clinical trial. Conventional CIs of the treatment effects ar...

Our part 1 series paper in peer review ...

Confidence intervals for adaptive trial designs I: A methodological review

arxiv.org/abs/2411.08495

14.11.2024 21:19 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Registration is open for the next Adaptive Designs and Multiple Testing Procedures Workshop (taking place on 26th-27th February 2025Β in Regensburg, Germany). For further details and to register, please seeΒ admtp.github.io/ADMTP2025/regi…

25.10.2024 19:45 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

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