Two diffraction photographs of B-DNA
I was not aware of that. Astbury's later student Elwyn Beighton got B-DNA diffraction photos in 1951 which are nearly as good as the famous "photograph 51". Astbury never published them, nor apparently did anything with them (from The Man in the Monkeynut Coat by Kersten Hall).
10.11.2025 13:08 — 👍 2 🔁 0 💬 0 📌 0
In 1916 the BMJ published an article about the work done by James Shearer, an American physician working in the British Army as a sergeant (because he had no British qualification). He had described a
"delineator" which was better than x rays for portraying gunshot wounds. This caused a sensation and a lot of interest — but on investigation the work was found to have been invented. The BMJ published a retraction, but Shearer was tried by court martial and sentenced to death by firing squad.
Next time an institution tells you how seriously it takes research misconduct, ask them if it's *this* seriously. www.bmj.com/content/297/...
13.10.2025 20:12 — 👍 640 🔁 233 💬 17 📌 21
Fermilab | History and Archives | People
"...this new knowledge has all to do with honor and country but it has nothing to do directly with defending our country except to help make it worth defending." RR Wilson congressional testimony justifying Fermilab (1969). history.fnal.gov/historical/p...
04.10.2025 19:44 — 👍 1 🔁 1 💬 0 📌 0
HOMEWORK MACHINE
The Homework Machine, oh the Homework Machine
Most perfect contraption that's ever been seen.
Just put in your homework, then drop in a dime,
Snap on the switch, and in ten seconds' time,
Your homework comes out, quick and clean as can be.
Here it is — "nine plus four?" and the answer is "three."
Three?
Oh me ...
I guess it's not as perfect
As I thought it would be.
shel silverstein on the LLM, 1981
10.06.2025 19:34 — 👍 1860 🔁 691 💬 10 📌 15
line graph of a CTF function, with initial guess and final refined parameter curves.
bitmaps of CTF modified image of a dartboard, corrected image (with phase flipping), and weiner filtered corrected image.
After some cajoling, got Gemini to vibe code cryoEM CTF fitting and correction. Other CTF fitting codes are available...
15.04.2025 20:23 — 👍 1 🔁 0 💬 0 📌 0
With GPT-4o I vibe-coded a crystal structure factor calculation, with refinement of atomic positions and output of sigmas. (This 1D demo extends to 2D with one more prompt). Very impressed.
15.04.2025 05:35 — 👍 1 🔁 0 💬 0 📌 0
Scientist & engineer in London, UK. Life, emergence, creativity, DEI, community-building, meditation, nature, psychonautics, dance. 🏳️🌈 jcxavier.org
PhD student at @ Stanford, Steinmetz Lab
Explaining cool new biotech to the world via TikTok/X
Professor of Bioinformatics. Executive Editor of the Database Issue at @narjournal.bsky.social. Proud Dad. Views my own.
Professor of Immunology, Head of Life Sciences, Imperial College London, author of The Compatibility Gene, The Beautiful Cure, The Secret Body and SELF DEFENCE (Penguin Random House)
We are Imperial College London's world-leading Life Sciences department. Where scientific imagination reveals our world, from molecules to ecosystems, and shapes its future.
Study with us / join our community: https://www.imperial.ac.uk/life-sciences
Cellular biochemistry of CO2 assimilation, NTU Singapore
Award-winning poltergeist and comedian | Writer of the Montgomery Bonbon mysteries | Pronouns like a butler coughing: he/him | linktr.ee/misterabk
UK TOUR 2026: www.mickperrin.com/tours/alasdair-beckett-king-king-of-crumbs
Assistant Professor in CS + AI at USC. Previously at Stanford, CMU. Machine Learning, Decision Making, AI-for-Science, Generative AI, ML Systems, LLMs.
https://willieneis.github.io
So far I have not found the science, but the numbers keep on circling me.
Views my own, unfortunately.
Safe and robust AI/ML, computational sustainability. Former President AAAI and IMLS. Distinguished Professor Emeritus, Oregon State University. https://web.engr.oregonstate.edu/~tgd/
DeepMind Professor of AI @Oxford
Scientific Director @Aithyra
Chief Scientist @VantAI
ML Lead @ProjectCETI
geometric deep learning, graph neural networks, generative models, molecular design, proteins, bio AI, 🐎 🎶
Knowledge based biomedical data science, artificial intelligence for discovery in molecular biomedicine, computational bioethics, theory of mattering. University of Chicago / Big Island HI
Professor, Santa Fe Institute. Research on AI, cognitive science, and complex systems.
Website: https://melaniemitchell.me
Substack: https://aiguide.substack.com/
Associate professor of social computing at UW CSE, leading @socialfutureslab.bsky.social
social.cs.washington.edu
AI for Science, deep generative models, inverse problems. Professor of AI and deep learning @universitedeliege.bsky.social. Previously @CERN, @nyuniversity. https://glouppe.github.io
Parent, spouse, Australian, Professor of Machine Learning in Oxford. Long Covid, trans rights, music, reggae on Fridays, AI must be good for humans, https://www.robots.ox.ac.uk/~mosb
Director Data Science Institute @UWMadison, Professor of Physics,
EiC @MLSTjournal. Physics, stats/ML/AI, open science.
AI + Astro/Physics. Assistant Prof at Cambridge.
astroautomata.com/
AI @ Pacific Fusion. Climate change monomaniac.
PhD @ Oxford. Prev: Carbon Re, DeepMind, FAIR, MSR, […]
🌍 / 🇪🇺 / 🇮🇹 / he / him.
Website: arbitrarygravitas.com
Recently a principal scientist at Google DeepMind. Joining Anthropic. Most (in)famous for inventing diffusion models. AI + physics + neuroscience + dynamical systems.